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Lysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src (Q36532023)

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scientific article published on October 1, 1992

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English	Lysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src	scientific article published on October 1, 1992

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Lysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

post-translational protein modification

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1400583

22 September 2022

author name string

L. Silverman

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1400583

22 September 2022

M. D. Resh

2

0000-0001-6118-9466

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1400583

22 September 2022

publication date

1 October 1992

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

October 1992

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1400583

11 July 2026

language of work or name

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number of pages

11

1 reference

based on heuristic

inferred from page(s)

work available at URL

https://europepmc.org/articles/PMC2289653

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1400583

22 September 2022

https://europepmc.org/articles/PMC2289653?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1400583

22 September 2022

https://rupress.org/jcb/article-pdf/119/2/415/1418435/415.pdf

online access status

content deliverer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1400583

11 July 2026

https://rupress.org/jcb/article-pdf/119/2/415/1473201/415.pdf

1 reference

10.1083/JCB.119.2.415

https://api.crossref.org/works/10.1083/JCB.119.2.415

11 July 2026

Journal of Cell Biology

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

119

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

415-425

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle

1 reference

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Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

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DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src.

1 reference

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The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane

1 reference

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30 September 2017

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1 reference

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High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range

1 reference

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30 September 2017

A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation

1 reference

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Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase

1 reference

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30 September 2017

In vitro synthesis of pp60v-src: myristylation in a cell-free system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

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The biology and enzymology of eukaryotic protein acylation

1 reference

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30 September 2017

NH2-terminal sequences of two src proteins that cause aberrant transformation

1 reference

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30 September 2017

Processing of p60v-src to its myristylated membrane-bound form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

Highly specific antibody to Rous sarcoma virus src gene product recognizes a novel population of pp60v-src and pp60c-src molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

The myristylation signal of p60v-src functionally complements the N-terminal fps-specific region of P130gag-fps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

1 reference

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30 September 2017

Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase

1 reference

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30 September 2017

N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene

1 reference

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30 September 2017

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1 reference

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

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The src protein contains multiple domains for specific attachment to membranes

1 reference

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Virus-specific messenger RNAs in permissive cells infected by avian sarcoma virus

1 reference

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Complete nucleotide sequence of SV40 DNA

1 reference

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30 September 2017

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2289653

30 September 2017

Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1 reference

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1 reference

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An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins

1 reference

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Myristylation of picornavirus capsid protein VP4 and its structural significance

1 reference

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Myristic acid is coupled to a structural protein of polyoma virus and SV40.

1 reference

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A mutation in the catalytic subunit of protein kinase A prevents myristylation but does not inhibit biological activity.

1 reference

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

1 reference

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Acylation of proteins with myristic acid occurs cotranslationally

1 reference

https://pubmed.ncbi.nlm.nih.gov/1400583

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based on heuristic

inferred from PubMed ID database lookup

The structure of the B subunit of calcineurin

1 reference

https://pubmed.ncbi.nlm.nih.gov/1400583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

1 reference

https://pubmed.ncbi.nlm.nih.gov/1400583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/1400583

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.119.2.415

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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