The role of recombinant human DNase in the treatment of patients with cystic fibrosis: many promises, more problems (Q36496558)

14 August 2017

1 reference

title

The role of recombinant human DNase in the treatment of patients with cystic fibrosis: many promises, more problems (English)

1 reference

14 August 2017

0 references

Zach MS

1

1 reference

PMC publication ID

472501

14 August 2017

language of work or name

English

0 references

publication date

1 July 1996

1 reference

14 August 2017

1 reference

14 August 2017

51

1 reference

14 August 2017

7

1 reference

14 August 2017

750-755

1 reference

DNase trials in cystic fibrosis

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Medium term treatment of stable stage cystic fibrosis with recombinant human DNase I.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

DNA concentration and length in sputum of patients with cystic fibrosis during inhalation with recombinant human DNase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Dornase alfa. A review of its pharmacological properties and therapeutic potential in cystic fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Dornase Aerosol Effect on Sputum Viscosity in Cases Of Cystic Fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Chest physiotherapy--the mechanical approach to antiinfective therapy in cystic fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Sputum changes associated with therapy for endobronchial exacerbation in cystic fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Recombinant human DNase I reduces the viscosity of cystic fibrosis sputum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Lung disease in cystic fibrosis--an updated concept

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Pus, deoxyribonucleic acid, and sputum viscosity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Effects of sputum from patients with cystic fibrosis on the activity in vitro of 5 antimicrobial drugs on Pseudomonas aeruginosa

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Deoxyribonuclease in the treatment of purulent bronchitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

rhDNase in cystic fibrosis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Measurement of sputum viscosity in a cone-plate viscometer. II. An evaluation of mucolytic agents in vitro.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

The role of mucus gel viscosity, spinnability, and adhesive properties in clearance by simulated cough

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Complex formation between basic antibiotics and deoxyribonucleic acid in human pulmonary secretions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

The role of mucous glycoproteins in the rheologic properties of cystic fibrosis sputum

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=472501

Chest physiotherapy in hospitalized patients with cystic fibrosis: a study of lung function effects and sputum production

21 September 2018

1 reference

12 December 2020

Dose-dependent in vitro effect of recombinant human DNase on rheological and transport properties of cystic fibrosis respiratory mucus

1 reference

12 December 2020

Rheological properties controlling mucociliary frequency and respiratory mucus transport

1 reference

12 December 2020

In-vitro evaluation of effect of enzymes on tracheobronchial secretions from patients withcystic fibrosis

1 reference

12 December 2020

Sputum peroxidase activity correlates with the severity of lung disease in cystic fibrosis

1 reference

12 December 2020

Aerosolized pancreatic dornase and antibiotics in pulmonary infections: use in patients with postoperative and nonoperative infections

1 reference

12 December 2020

Efficacy and safety of short-term administration of aerosolized recombinant human deoxyribonuclease in patients with cystic fibrosis

1 reference

12 December 2020

Effects of combined treatment with rhDNase and airflow oscillations on spinnability of cystic fibrosis sputum in vitro

1 reference

12 December 2020

STUDIES ON PULMONARY SECRETIONS. I. THE OVER-ALL CHEMICAL COMPOSITION OF PULMONARY SECRETIONS FROM PATIENTS WITH CYSTIC FIBROSIS, BRONCHIECTASIS, AND LARYNGECTOMY

1 reference

12 December 2020

The changing epidemiology of cystic fibrosis

1 reference

12 December 2020

Two years experience with recombinant human DNase I in the treatment of pulmonary disease in cystic fibrosis

1 reference

12 December 2020

The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis

1 reference

12 December 2020

A preliminary study of aerosolized recombinant human deoxyribonuclease I in the treatment of cystic fibrosis

1 reference

12 December 2020

Distearoyl phosphatidylglycerol liposomes improve surface and transport properties of CF mucus

1 reference

12 December 2020

Bioactivity of gentamicin in purulent sputum from patients with cystic fibrosis or bronchiectasis: comparison with activity in serum

1 reference

12 December 2020

Neutrophil collagenase in sputum from patients with cystic fibrosis

1 reference

12 December 2020

Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation

1 reference

12 December 2020

Aminoglycoside penetration, inactivation, and efficacy in cystic fibrosis sputum

1 reference

12 December 2020

The origin of DNA associated with mucus glycoproteins in cystic fibrosis sputum

1 reference

12 December 2020

Efficacy and safety of short-term administration of aerosolised recombinant human DNase I in adults with stable stage cystic fibrosis

1 reference

12 December 2020

Aerosols of pancreatic dornase in bronchopulmonary disease

1 reference

12 December 2020

Recombinant human DNase inhalation in normal subjects and patients with cystic fibrosis. A phase 1 study

1 reference

12 December 2020

Composition of tracheobronchial secretions in cystic fibrosis of the pancreas and bronchiectasis

1 reference

12 December 2020

The binding of anti-pseudomonal antibiotics to macromolecules from cystic fibrosis sputum

1 reference

12 December 2020

The binding of amikacin to macromolecules from the sputum of patients suffering from respiratory diseases

1 reference

12 December 2020

Liquefaction of viscous purulent exudates by deoxyribonuclease

1 reference

12 December 2020

Identifiers

DOI

10.1136/THX.51.7.750

1 reference

14 August 2017

1 reference

PMC publication ID

472501

14 August 2017

PubMed publication ID

8882085

1 reference

PMC publication ID

472501