Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activation (Q36435313)

14 August 2017

Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activation (English)

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14 August 2017

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4

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9 June 2020

author name string

Nathalie Knies

1

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9 June 2020

Begüm Alankus

2

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9 June 2020

Andre Weilemann

3

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9 June 2020

Kristina Brunner

5

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9 June 2020

Tanja Ruff

6

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9 June 2020

Marcus Kremer

7

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9 June 2020

Ulrich B Keller

8

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9 June 2020

Georg Lenz

9

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9 June 2020

Jürgen Ruland

10

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9 June 2020

language of work or name

English

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publication date

14 December 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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9 June 2020

volume

112

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9 June 2020

issue

52

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9 June 2020

page(s)

E7230-8

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Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma.

9 June 2020

cites work

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DUSP4 deficiency caused by promoter hypermethylation drives JNK signaling and tumor cell survival in diffuse large B cell lymphoma

30 September 2017

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c-JUN N-terminal kinase (JNK) is activated and contributes to tumor cell proliferation in classical Hodgkin lymphoma

30 September 2017

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Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation

30 September 2017

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Ibrutinib (PCI-32765), the first BTK (Bruton's tyrosine kinase) inhibitor in clinical trials

30 September 2017

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Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production.

30 September 2017

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Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor

30 September 2017

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T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

30 September 2017

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Immunohistochemical methods for predicting cell of origin and survival in patients with diffuse large B-cell lymphoma treated with rituximab

30 September 2017

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Oncogenic CARD11 Mutations Induce Hyperactive Signaling by Disrupting Autoinhibition by the PKC-Responsive Inhibitory Domain

30 September 2017

1 reference

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Oncogenic activation of NF-kappaB.

30 September 2017

1 reference

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The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma

30 September 2017

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30 September 2017

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Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

30 September 2017

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Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

30 September 2017

1 reference

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Comprehending the complex connection between PKCbeta, TAK1, and IKK in BCR signaling

30 September 2017

1 reference

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Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells

30 September 2017

1 reference

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JNK is constitutively active in mantle cell lymphoma: cell cycle deregulation and polyploidy by JNK inhibitor SP600125.

30 September 2017

1 reference

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Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival

30 September 2017

1 reference

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Stromal gene signatures in large-B-cell lymphomas

30 September 2017

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Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

30 September 2017

1 reference

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The proteolytic activity of the paracaspase MALT1 is key in T cell activation

30 September 2017

1 reference

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T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

30 September 2017

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The CARMA1-Bcl10 signaling complex selectively regulates JNK2 kinase in the T cell receptor-signaling pathway

30 September 2017

1 reference

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Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors

30 September 2017

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A loss-of-function RNA interference screen for molecular targets in cancer

30 September 2017

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Phosphorylation of the CARMA1 linker controls NF-kappaB activation

30 September 2017

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PKC beta regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1

30 September 2017

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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

30 September 2017

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Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: an ECSG/EORTC study

30 September 2017

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Regulation of plasma-cell development

30 September 2017

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Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

30 September 2017

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B cell antigen receptor signaling 101.

30 September 2017

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Differential Requirement for Malt1 in T and B Cell Antigen Receptor Signaling

30 September 2017

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The MAGUK family protein CARD11 is essential for lymphocyte activation

30 September 2017

1 reference

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Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B.

30 September 2017

1 reference

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

30 September 2017

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AP-1 in mouse development and tumorigenesis

30 September 2017

1 reference

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Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

30 September 2017

1 reference

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

30 September 2017

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B lymphocyte-specific, Cre-mediated mutagenesis in mice

30 September 2017

1 reference

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4702996

Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation

30 September 2017

1 reference

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Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma

28 June 2018

1 reference

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Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

28 June 2018

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Anticancer agent CHS 828 suppresses nuclear factor-kappa B activity in cancer cells through downregulation of IKK activity

28 June 2018

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Survival signaling mediated by c-Jun NH(2)-terminal kinase in transformed B lymphoblasts.

21 September 2018

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Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells.

21 September 2018

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Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1507459112

21 January 2018

Identifiers

DOI

10.1073/PNAS.1507459112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26668357%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

0 references

1 reference

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9 June 2020

PubMed publication ID

26668357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26668357%20AND%20SRC:MED&resulttype=core&format=json