Commitment issues: linking positive selection signals and lineage diversification in the thymus (Q36382781)

13 August 2017

title

Commitment issues: linking positive selection signals and lineage diversification in the thymus (English)

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13 August 2017

Parinaz Aliahmad

1

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13 August 2017

Jonathan Kaye

series ordinal

2

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13 August 2017

publication date

1 February 2006

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13 August 2017

language of work or name

English

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published in

Immunological Reviews

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13 August 2017

volume

209

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13 August 2017

page(s)

253-273

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publication type of scholarly work

13 August 2017

review article

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Thymic involution with ageing: obsolescence or good housekeeping?

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An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection

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Another view of the selective model of thymocyte selection

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Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

21 January 2018

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Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo

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In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells

21 January 2018

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Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

21 January 2018

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Requirement for sustained MAPK signaling in both CD4 and CD8 lineage commitment: a threshold model

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Duration of calcineurin and Erk signals regulates CD4/CD8 lineage commitment of thymocytes

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Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

21 January 2018

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Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

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An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

21 January 2018

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The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate

21 January 2018

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Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

21 January 2018

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Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development

21 January 2018

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The role of Notch signaling during hematopoietic lineage commitment

21 January 2018

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Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation

21 January 2018

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Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling

21 January 2018

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Receptor signals and nuclear events in CD4 and CD8 T cell lineage commitment

21 January 2018

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The Ras/MAPK cascade and the control of positive selection

21 January 2018

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The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells

21 January 2018

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Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail

21 January 2018

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Lck activity controls CD4/CD8 T cell lineage commitment.

21 January 2018

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Selective requirement for MAP kinase activation in thymocyte differentiation

21 January 2018

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Calcineurin B1 is essential for positive but not negative selection during thymocyte development

21 January 2018

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Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

21 January 2018

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Positive Selection Through a Motif in the αβ T Cell Receptor

21 January 2018

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A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

21 January 2018

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Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Abnormal differentiation of thymocytes in mice treated with cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Defective T cell development and function in calcineurin A beta -deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Back in the water: the return of the inositol phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

The Influence of the MAPK Pathway on T Cell Lineage Commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Regulation of lineage commitment distinct from positive selection

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Induction of the early growth response (Egr) family of transcription factors during thymic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Early growth response (Egr)-1 gene induction in the thymus in response to TCR ligation during early steps in positive selection is not required for CD8 lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Thymocyte development in early growth response gene 1-deficient mice

21 January 2018

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Id helix—loop—helix proteins in cell growth and differentiation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Reorganization of pontine rhythmogenic neuronal networks in Krox-20 knockout mice

21 January 2018

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NF-AT components define a family of transcription factors targeted in T-cell activation

21 January 2018

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The Transcription Factor NFAT4 Is Involved in the Generation and Survival of T Cells

21 January 2018

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Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development

21 January 2018

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NFATc2 and NFATc3 regulate TH2 differentiation and modulate TCR-responsiveness of naïve TH cells

21 January 2018

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Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

21 January 2018

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Successive expression and activation of NFAT family members during thymocyte differentiation

21 January 2018

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TOX: an HMG box protein implicated in the regulation of thymocyte selection

21 January 2018

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TOX defines a conserved subfamily of HMG-box proteins

21 January 2018

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HMG1 and 2, and related 'architectural' DNA-binding proteins

21 January 2018

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Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding

21 January 2018

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Interaction with p53 enhances binding of cisplatin-modified DNA by high mobility group 1 protein

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21 January 2018

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Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes

21 January 2018

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The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding

21 January 2018

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Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells

21 January 2018

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TOX provides a link between calcineurin activation and CD8 lineage commitment

21 January 2018

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Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells

21 January 2018

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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development

21 January 2018

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DNA recognition by the RUNX1 transcription factor is mediated by an allosteric transition in the RUNT domain and by DNA bending

21 January 2018

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SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo

21 January 2018

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The core-binding factor leukemias: lessons learned from murine models

21 January 2018

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Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

21 January 2018

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

21 January 2018

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c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin

21 January 2018

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c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis

21 January 2018

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The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment

21 January 2018

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HD mice: A novel mouse mutant with a specific defect in the generation of CD4+T cells

21 January 2018

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GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

21 January 2018

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Transcriptional regulation of T lymphocyte development and function

21 January 2018

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Critical roles for transcription factor GATA-3 in thymocyte development

21 January 2018

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CD83 expression influences CD4+ T cell development in the thymus

21 January 2018

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Haematopoietic cell-fate decisions, chromatin regulation and ikaros

21 January 2018

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Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

21 January 2018

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The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development

21 January 2018

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Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

21 January 2018

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Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

The CD8alpha gene locus is regulated by the Ikaros family of proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Ikaros null mice display defects in T cell selection and CD4 versus CD8 lineage decisions

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2

21 January 2018

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Schnurri-3 (KRC) interacts with c-Jun to regulate the IL-2 gene in T cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Murine Schnurri-2 is required for positive selection of thymocytes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

The role of erk1 and erk2 in multiple stages of T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Vav1 Transduces T Cell Receptor Signals to the Activation of the Ras/ERK Pathway via LAT, Sos, and RasGRP1

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2006.00345.X

10.1111/J.0105-2896.2006.00345.X

21 January 2018

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DOI

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13 August 2017

1 reference