The chemistry and biology of mucin-type O-linked glycosylation (Q36187831)

12 August 2017

title

The chemistry and biology of mucin-type O-linked glycosylation (English)

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12 August 2017

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2

Carolyn R Bertozzi

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12 August 2017

Howard C Hang

1

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12 August 2017

publication date

1 September 2005

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Bioorganic & Medicinal Chemistry

12 August 2017

language of work or name

English

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published in

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12 August 2017

volume

13

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12 August 2017

issue

17

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12 August 2017

page(s)

5021-5034

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publication type of scholarly work

12 August 2017

review article

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cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii

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5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Identification and separation of two distinct transferase activities.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Metabolic labeling of glycoproteins with chemical tags through unnatural sialic acid biosynthesis

2 references

5 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0076-6879(00)27282-0

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

cDNA Cloning and Expression of a Family of UDP-N-acetyl-dgalactosamine:PolypeptideN-Acetylgalactosaminyltransferase Sequence Homologs fromCaenorhabditis elegans

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Fold recognition and molecular modeling of a lectin-like domain in UDP- GalNac:polypeptide N-acetylgalactosaminyltransferases

0 references

Structural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistance

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

N-acetylgalactosamine incorporation into a peptide containing consecutive threonine residues by UDP-N-acetyl-D-galactosaminide:polypeptide N-acetylgalactosaminyltransferases

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Identification of essential histidine residues in UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T1

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Conformational influences of glycosylation of a peptide: a possible model for the effect of glycosylation on the rate of protein folding

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Proteomic analysis of post-translational modifications

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination

0 references

Identification of a recurrent mutation in GALNT3 demonstrates that hyperostosis-hyperphosphatemia syndrome and familial tumoral calcinosis are allelic disorders

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs

0 references

Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

A novel human UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, GalNAc-T7, with specificity for partial GalNAc-glycosylated acceptor substrates

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Charge distribution of flanking amino acids influences O-glycan acquisition in vivo

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli

0 references

GalNAc-alpha-O-benzyl inhibits NeuAcalpha2-3 glycosylation and blocks the intracellular transport of apical glycoproteins and mucus in differentiated HT-29 cells.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

An evolving hierarchical family classification for glycosyltransferases

0 references

Glycosylation and the immune system

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

The beginnings of mucin biosynthesis: the crystal structure of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-T1.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

A UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is essential for viability in Drosophila melanogaster

0 references

Brain-specific expression of a novel human UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T9)

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

In vivo glycosylation of mucin tandem repeats

0 references

Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Disaccharide uptake and priming in animal cells: inhibition of sialyl Lewis X by acetylated Gal beta 1-->4GlcNAc beta-O-naphthalenemethanol

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14

0 references

Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Structures of the major carbohydrates of natural human interleukin-2.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Probing glycosyltransferase activities with the Staudinger ligation

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/citations/10.1021/JA037692M

Prediction, conservation analysis, and structural characterization of mammalian mucin-type O-glycosylation sites

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

A chemical switch for inhibitor-sensitive alleles of any protein kinase

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Support vector machines for predicting the specificity of GalNAc-transferase

0 references

Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Influence of the amino acid sequence on the MUC5AC motif peptide O-glycosylation by human gastric UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase(s)

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Chemoenzymatic synthesis of biotinylated nucleotide sugars as substrates for glycosyltransferases

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

O-GLYCBASE version 4.0: a revised database of O-glycosylated proteins

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Semisynthesis of proteins by expressed protein ligation

0 references

MUC1: the polymorphic appearance of a human mucin

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

THE QUANTITATIVE DETERMINATION OF INFLUENZA VIRUS AND ANTIBODIES BY MEANS OF RED CELL AGGLUTINATION.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Mucin-Type Glycoproteins

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Kinetic analysis of a recombinant UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold

0 references

Mutations in GALNT3, encoding a protein involved in O-linked glycosylation, cause familial tumoral calcinosis

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Incorporation of N-acetylgalactosamine into consecutive threonine residues in MUC2 tandem repeat by recombinant human N-acetyl-D-galactosamine transferase-T1, T2 and T3.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Engineering neoglycoproteins with multiple O-glycans using repetitive pentapeptide glycosylation units

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Toward optimized carbohydrate-based anticancer vaccines: epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewis(y) conjugates in mice

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Fucosylation of Disaccharide Precursors of Sialyl LewisX Inhibit Selectin-mediated Cell Adhesion

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Catalytic mechanism of enzymic glycosyl transfer

0 references

Ligands for L-selectin: homing, inflammation, and beyond

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Determination of the site-specific O-glycosylation pattern of the porcine submaxillary mucin tandem repeat glycopeptide. Model proposed for the polypeptide:galnac transferase peptide binding site

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Characterization of a UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase that displays glycopeptide N-acetylgalactosaminyltransferase activity

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Model Glycosulfopeptides from P-selectin Glycoprotein Ligand-1 Require Tyrosine Sulfation and a Core 2-branched O-Glycan to Bind to L-selectin

0 references

Isoform-specific O-glycosylation by murine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3, in vivo

0 references

Glycosulfopeptides with O-glycans containing sialylated and polyfucosylated polylactosamine bind with low affinity to P-selectin

0 references

Glycans as legislators of host-microbial interactions: spanning the spectrum from symbiosis to pathogenicity

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Organization of a human UDP-GalNAc:polypeptide, N-acetylgalactosaminyltransferase gene and a related processed pseudogene

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

The structure and assembly of secreted mucins

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

A genetic approach to Mammalian glycan function

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Targeting glycosylation as a therapeutic approach

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase isoforms in murine tissues determined by real-time PCR: a new view of a large family

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Identification of two cysteine residues involved in the binding of UDP-GalNAc to UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1).

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Roles of mucin-type O-glycans in cell adhesion

0 references

Perspectives series: cell adhesion in vascular biology. Role of PSGL-1 binding to selectins in leukocyte recruitment

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Chemical glycobiology

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

The acceptor specificity of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Trapping of alpha-glycosidase intermediates

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Glycosylation of the Tandem Repeat Unit of the MUC2 Polypeptide Leading to the Synthesis of the Tn Antigen

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells

0 references

Substrate recognition by UDP-N-acetyl-alpha-D-galactosamine: polypeptide n-acetyl-alpha-D-galactosaminyltransferase. Effects of chain length and disulphide bonding of synthetic peptide substrates

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

The AATPAP sequence is a very efficient signal for O-glycosylation in CHO cells

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Roles of O-linked oligosaccharides in immune responses

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

The lectin domain of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 is involved in O-glycosylation of a polypeptide with multiple acceptor sites

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Mechanistic studies of a retaining alpha-galactosyltransferase from Neisseria meningitidis.

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Discovery of the shortest sequence motif for high level mucin-type O-glycosylation

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

The contribution of tandem repeat number to the O-glycosylation of mucins

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Convergent total synthesis of a tumour-associated mucin motif

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Pathways of O-glycan biosynthesis in cancer cells

0 references

A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry

0 references

Expanding the Genetic Code

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Unnatural ligands for engineered proteins: new tools for chemical genetics

0 references

Mucin core O-glycosylation is modulated by neighboring residue glycosylation status. Kinetic modeling of the site-specific glycosylation of the apo-porcine submaxillary mucin tandem repeat by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Haemagglutination in relation to host cell-virus interaction

0 references

Light and electron microscopic immunolocalization of rat submandibular gland mucin glycoprotein and glutamine/glutamic acid-rich proteins

0 references

Evolution of Lutropin to Chorionic Gonadotropin Generates a Specific Routing Signal for Apical Release in Vivo

0 references

CD45: a critical regulator of signaling thresholds in immune cells

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Genomic organization and chromosomal localization of three members of the UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase family

0 references

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

1 reference

5 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA

0 references

Glycosylation mutants of animal cells

0 references

Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation

0 references

Conserved domains of glycosyltransferases

0 references

Stereoselective synthesis of phosphoramidate α(2-6)Sialyltransferase transition-State analogue inhibitors

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury

1 reference

8 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2005.04.085

Identifiers

DOI

10.1016/J.BMC.2005.04.085

1 reference

12 August 2017

1 reference