Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence (Q36082300)

12 August 2017

Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence (English)

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12 August 2017

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12

Thomas Werge

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12 August 2017

Kim Q Do

14

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author name string

René Gysin

1

1 reference

12 August 2017

Rudolf Kraftsik

2

1 reference

12 August 2017

Julie Sandell

3

1 reference

12 August 2017

Pierre Bovet

4

1 reference

12 August 2017

Céline Chappuis

5

1 reference

12 August 2017

Philippe Conus

6

1 reference

12 August 2017

Patricia Deppen

7

1 reference

12 August 2017

Martin Preisig

8

1 reference

12 August 2017

Viviane Ruiz

9

1 reference

12 August 2017

Pascal Steullet

10

1 reference

12 August 2017

Mirjana Tosic

11

1 reference

12 August 2017

Michel Cuénod

13

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12 August 2017

language of work or name

English

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publication date

5 October 2007

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Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

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12 August 2017

104

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12 August 2017

16621-16626

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12 August 2017

42

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Schizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility gene

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Schizophrenia: an integrative approach to modelling a complex disorder.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Altered glutathione redox state in schizophrenia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: relevance to schizophrenia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Schizophrenia: genes at last?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Cortical inhibitory neurons and schizophrenia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Cardiovascular disease in patients with schizophrenia in Saskatchewan, Canada.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Association of polymorphism in glutamate-cysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Schizophrenia as a disorder of neurodevelopment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Evidence for functionally significant polymorphism of human glutamate cysteine ligase catalytic subunit: association with glutathione levels and drug resistance in the National Cancer Institute tumor cell line panel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Glutathione, oxidative stress and neurodegeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Multi-faceted regulation of gamma-glutamylcysteine synthetase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

The molecular basis of a case of gamma-glutamylcysteine synthetase deficiency

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Chemical and molecular regulation of enzymes that detoxify carcinogens

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Energetics of functional activation in neural tissues.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2034265

Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo.

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Possible involvement of free radicals in the differential neurobehavioral responses to stress in male and female rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Glutathione biosynthesis and its inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Transitory glutathione deficit during brain development induces cognitive impairment in juvenile and adult rats: relevance to schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Low brain glutathione and ascorbic acid associated with dopamine uptake inhibition during rat's development induce long-term cognitive deficit: relevance to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: Relevance to schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Dopamine-induced oxidative stress in neurons with glutathione deficit: implication for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Diagnostic interview for genetic studies (DIGS): inter-rater and test-retest reliability of the French version.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706778104

Missense mutations in the human glutathione synthetase gene result in severe metabolic acidosis, 5-oxoprolinuria, hemolytic anemia and neurological dysfunction

21 January 2018

1 reference

12 December 2020

A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6

1 reference

12 December 2020

Serious cardiovascular events and mortality among patients with schizophrenia

1 reference

12 December 2020

Neurobiology of schizophrenia

1 reference

12 December 2020

gamma-Glutamylglutamine and taurine concentrations are decreased in the cerebrospinal fluid of drug-naive patients with schizophrenic disorders

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0706778104

1 reference

12 August 2017

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12 August 2017

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