Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome (Q35935216)

11 August 2017

Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome (English)

1 reference

Proteasome regulatory particle base subunit RPN1 YHR027C

11 August 2017

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

4

Bradley B. Stocks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

27 January 2026

6

Byung-Hoon Lee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

27 January 2026

14

John R. Engen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

27 January 2026

author name string

Yuan Shi

1

1 reference

11 August 2017

Xiang Chen

2

1 reference

11 August 2017

Suzanne Elsasser

3

1 reference

11 August 2017

Geng Tian

5

1 reference

11 August 2017

Yanhong Shi

7

1 reference

11 August 2017

Naixia Zhang

8

1 reference

11 August 2017

Fabian Tuebing

10

1 reference

11 August 2017

Shuangwu Sun

11

1 reference

11 August 2017

Jacob Vannoy

12

1 reference

11 August 2017

Daniel Finley

15

1 reference

11 August 2017

Stefanie A. H. de Poot

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

27 January 2026

Sergey G. Tarasov

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

27 January 2026

Kylie J. Walters

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

27 January 2026

publication date

1 February 2016

1 reference

11 August 2017

19 February 2016

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=26912900

https://doi.org/10.1126/science.aad9421

27 January 2026

language of work or name

English

0 references

work available at URL

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

https://europepmc.org/articles/PMC4980823

27 January 2026

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

https://europepmc.org/articles/PMC4980823?pdf=render

27 January 2026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A26912900

https://www.science.org/doi/pdf/10.1126/science.aad9421

27 January 2026

1 reference

Crossref

DOI

10.1126/SCIENCE.AAD9421

https://api.crossref.org/works/10.1126/SCIENCE.AAD9421

27 January 2026

1 reference

11 August 2017

351

1 reference

11 August 2017

6275

1 reference

describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4980823/fullTextXML

inferred from PubMed Central ID database lookup

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Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome

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Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase

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Transfer of Ho Endonuclease and Ufo1 to the Proteasome by the UbL-UbA Shuttle Protein, Ddi1, Analysed by Complex Formation In Vitro

2 October 2017

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Probing protein interactions with hydrogen/deuterium exchange and mass spectrometry—A review

2 October 2017

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The structure of the 26S proteasome subunit Rpn2 reveals its PC repeat domain as a closed toroid of two concentric α-helical rings

2 October 2017

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Binding of Ubiquitin Conjugates to Proteasomes as Visualized with Native Gels

2 October 2017

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Rpn1 and Rpn2 coordinate ubiquitin processing factors at proteasome

2 October 2017

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APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

2 October 2017

1 reference

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Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

2 October 2017

1 reference

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Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1

2 October 2017

1 reference

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The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies

2 October 2017

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CPORT: a consensus interface predictor and its performance in prediction-driven docking with HADDOCK.

2 October 2017

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Hydrogen exchange mass spectrometry for studying protein structure and dynamics

2 October 2017

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Enhancement of proteasome activity by a small-molecule inhibitor of USP14

2 October 2017

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Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2

2 October 2017

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Multitasking with ubiquitin through multivalent interactions

2 October 2017

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Structure of the S5a:K48-Linked Diubiquitin Complex and Its Interactions with Rpn13

2 October 2017

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Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome.

2 October 2017

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High-speed and high-resolution UPLC separation at zero degrees Celsius

2 October 2017

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Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution

2 October 2017

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Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches.

2 October 2017

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Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction

2 October 2017

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Proteasome subunit Rpn13 is a novel ubiquitin receptor

2 October 2017

1 reference

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Yeast UBL-UBA proteins have partially redundant functions in cell cycle control.

2 October 2017

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Practical aspects of (1)H transverse paramagnetic relaxation enhancement measurements on macromolecules.

2 October 2017

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Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

2 October 2017

1 reference

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Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis

2 October 2017

1 reference

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Partial unfolding of diverse SH3 domains on a wide timescale

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Hydrogen exchange mass spectrometry for the analysis of protein dynamics

2 October 2017

1 reference

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Mapping protein energy landscapes with amide hydrogen exchange and mass spectrometry: I. A generalized model for a two-state protein and comparison with experiment.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Global analysis of protein expression in yeast

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Multiple associated proteins regulate proteasome structure and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Proteasome subunit Rpn1 binds ubiquitin-like protein domains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

The 19S complex of the proteasome regulates nucleotide excision repair in yeast.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Utilization of site-directed spin labeling and high-resolution heteronuclear nuclear magnetic resonance for global fold determination of large proteins with limited nuclear overhauser effect data

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Pleiotropic defects caused by loss of the proteasome-interacting factors Rad23 and Rpn10 of Saccharomyces cerevisiae.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

A 26 S protease subunit that binds ubiquitin conjugates

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Meta-analysis of Ubiquilin1 gene polymorphism and Alzheimer’s disease risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Dss1 is a 26S proteasome ubiquitin receptor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Ubiquitin chain synthesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

An unstructured initiation site is required for efficient proteasome-mediated degradation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4980823

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.AAD9421

What curves alpha-solenoids? Evidence for an alpha-helical toroid structure of Rpn1 and Rpn2 proteins of the 26 S proteasome

21 January 2018

1 reference

12 December 2020

Purification of proteasomes, proteasome subcomplexes, and proteasome-associated proteins from budding yeast

1 reference

12 December 2020

Identifying and Studying Ubiquitin Receptors by NMR

1 reference

12 December 2020

Hydrogen exchange-mass spectrometry: optimization of digestion conditions

1 reference

12 December 2020

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

12 December 2020

Preparation of ubiquitinated substrates by the PY motif-insertion method for monitoring 26S proteasome activity

1 reference

12 December 2020

Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.AAD9421

1 reference

11 August 2017

1 reference

11 August 2017

1 reference