DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies (Q35765428)

10 August 2017

title

DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies (English)

1 reference

10 August 2017

main subject

chromosome abnormality

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9588877

22 December 2024

gene dosage

1 reference

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22 December 2024

author name string

S. Knuutila

1

1 reference

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22 December 2024

A. M. Björkqvist

2

1 reference

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22 December 2024

K. Autio

3

1 reference

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22 December 2024

M. Tarkkanen

4

1 reference

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22 December 2024

M. Wolf

5

1 reference

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22 December 2024

O. Monni

6

1 reference

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22 December 2024

J. Szymanska

7

1 reference

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22 December 2024

M. L. Larramendy

8

1 reference

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22 December 2024

J. Tapper

9

1 reference

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22 December 2024

H. Pere

10

1 reference

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22 December 2024

W. El-Rifai

11

1 reference

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22 December 2024

S. Hemmer

12

1 reference

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22 December 2024

V. M. Wasenius

13

1 reference

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22 December 2024

V. Vidgren

14

1 reference

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22 December 2024

Y. Zhu

15

1 reference

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22 December 2024

publication date

1 May 1998

1 reference

10 August 2017

May 1998

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9588877

http://ajp.amjpathol.org/cgi/content/abstract/152/5/1107

22 December 2024

language of work or name

English

0 references

work available at URL

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9588877

https://europepmc.org/articles/PMC1858578

22 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9588877

https://europepmc.org/articles/PMC1858578?pdf=render

22 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9588877

The American Journal of Pathology

22 December 2024

published in

1 reference

10 August 2017

volume

152

1 reference

10 August 2017

issue

5

1 reference

10 August 2017

page(s)

1107-1123

1 reference

publication type of scholarly work

10 August 2017

review article

1 reference

Comparison of DNA copy number changes in malignant mesothelioma, adenocarcinoma and large-cell anaplastic carcinoma of the lung

cites work

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2 October 2017

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Genome screening by comparative genomic hybridization

2 October 2017

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Comparative genomic hybridization of malignant fibrous histiocytoma reveals a novel prognostic marker

2 October 2017

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AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

2 October 2017

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High-level DNA amplifications are common genetic aberrations in B-cell neoplasms.

2 October 2017

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Characterization of a high copy number amplification at 6q24 in pancreatic cancer identifies c-myb as a candidate oncogene

2 October 2017

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Evidence for divergence of DNA copy number changes in serous, mucinous and endometrioid ovarian carcinomas

2 October 2017

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Amplification of the genes BCHE and SLC2A2 in 40% of squamous cell carcinoma of the lung

2 October 2017

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A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

2 October 2017

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Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization

2 October 2017

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Ring chromosomes in parosteal osteosarcoma contain sequences from 12q13-15: a combined cytogenetic and comparative genomic hybridization study

2 October 2017

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Genetic changes in intraductal breast cancer detected by comparative genomic hybridization.

2 October 2017

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Gains, losses, and amplifications of DNA sequences evaluated by comparative genomic hybridization in chondrosarcomas

2 October 2017

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Comparison of DNA gains and losses in primary renal clear cell carcinomas and metastatic sites: importance of 1q and 3p copy number changes in metastatic events

2 October 2017

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Gain of chromosome 17 is the most frequent abnormality detected in neuroblastoma by comparative genomic hybridization

2 October 2017

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Translation initiation factor eIF-4gamma is encoded by an amplified gene and induces an immune response in squamous cell lung carcinoma

2 October 2017

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Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p

2 October 2017

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Use of a cDNA microarray to analyse gene expression patterns in human cancer

2 October 2017

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Mybl2 (Bmyb) maps to mouse chromosome 2 and human chromosome 20q 13.1.

2 October 2017

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Gains, losses, and amplification of genomic material in rhabdomyosarcoma analyzed by comparative genomic hybridization

2 October 2017

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Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer

2 October 2017

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DNA amplification on chromosome 3q26.1-q26.3 in squamous cell carcinoma of the lung detected by reverse chromosome painting

2 October 2017

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Application of a simplified comparative genomic hybridization technique to screen for gene amplification in pediatric solid tumors

2 October 2017

1 reference

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Comparative genomic hybridization of germ cell tumors of the adult testis: confirmation of karyotypic findings and identification of a 12p-amplicon

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1858578

Clinically distinct subgroups of glioblastoma multiforme studied by comparative genomic hybridization.

2 October 2017

1 reference

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Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix

2 October 2017

1 reference

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Comparative genomic hybridization analysis of human sarcomas: I. Occurrence of genomic imbalances and identification of a novel major amplicon at 1q21-q22 in soft tissue sarcomas

2 October 2017

1 reference

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Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins

2 October 2017

1 reference

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Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas

2 October 2017

1 reference

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Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses

2 October 2017

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MYCN is retained in single copy at chromosome 2 band p23-24 during amplification in human neuroblastoma cells

2 October 2017

1 reference

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Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

2 October 2017

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Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples

2 October 2017

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Chromosomal abnormalities in glioblastoma multiforme tumors and glioma cell lines detected by comparative genomic hybridization.

2 October 2017

1 reference

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The human OTF1 locus which overlaps the CD3Z gene is located at 1q22-->q23

2 October 2017

1 reference

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The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas

2 October 2017

1 reference

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In vivo amplification of the androgen receptor gene and progression of human prostate cancer

2 October 2017

1 reference

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Detection of chromosomal imbalances in transitional cell carcinoma of the bladder by comparative genomic hybridization

2 October 2017

1 reference

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Correlation of microscopic phenotype with genotype in a formalin-fixed, paraffin-embedded testicular germ cell tumor with universal DNA amplification, comparative genomic hybridization, and interphase cytogenetics

2 October 2017

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Quantitative analysis of comparative genomic hybridization

2 October 2017

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Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours

2 October 2017

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Direct visualization of the clonal progression of primary cutaneous melanoma: application of tissue microdissection and comparative genomic hybridization

2 October 2017

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Comparative genomic hybridization in acute myeloid leukemia. A comparison with G-banding and chromosome painting

2 October 2017

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Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer

2 October 2017

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Comparative genomic hybridization in the investigation of myeloid leukemias

2 October 2017

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Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

2 October 2017

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Complex composition and co-amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well-differentiated liposarcoma

2 October 2017

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Amplification of cellular oncogenes: a predictor of clinical outcome in human cancer

2 October 2017

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Amplification of a gene encoding a p53-associated protein in human sarcomas

2 October 2017

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Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

2 October 2017

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Genetic alterations in primary breast cancers and their metastases: direct comparison using modified comparative genomic hybridization

2 October 2017

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Molecular cytogenetic abnormalities in multiple myeloma and plasma cell leukemia measured using comparative genomic hybridization

12 July 2018

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Report of the second international workshop on human chromosome 1 mapping 1995.

12 July 2018

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Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.

12 July 2018

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Genetic aberrations in adrenocortical tumors detected using comparative genomic hybridization correlate with tumor size and malignancy

12 July 2018

1 reference

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Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping

12 July 2018

1 reference

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Genetic analysis of benign, low-grade, and high-grade ovarian tumors

12 July 2018

1 reference

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Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2.

12 July 2018

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Identification of novel regions of altered DNA copy number in small cell lung tumors

12 July 2018

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Frequent novel DNA copy number increase in squamous cell head and neck tumors

12 July 2018

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Distinct chromosomal imbalances in uterine serous and endometrioid carcinomas

12 July 2018

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Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization

25 September 2018

1 reference

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Malignant astrocytoma-derived region of common amplification in chromosomal band 17p12 is frequently amplified in high-grade osteosarcomas

25 September 2018

1 reference

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Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization.

25 September 2018

1 reference

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Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors

25 September 2018

1 reference

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Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization

25 September 2018

1 reference

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Detection of complex genetic alterations in human glioblastoma multiforme using comparative genomic hybridization.

25 September 2018

1 reference

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Heterogeneity of erbB-2 gene amplification in bladder cancer

25 September 2018

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Report and abstracts of the First International Workshop on Human Chromosome 1 Mapping 1994. Bethesda, Maryland, March 25-27, 1994.

25 September 2018

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Comparative genomic hybridization in the detection of DNA copy number abnormalities in uveal melanoma.

25 September 2018

1 reference

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Comparative genomic hybridization analysis of breast tumors with predetermined profiles of DNA amplification

25 September 2018

1 reference

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Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization

25 September 2018

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12 December 2020

Overrepresentation of 1q21-23 and 12q13-21 in lipoma-like liposarcomas but not in benign lipomas: a comparative genomic hybridization study

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12 December 2020

Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity

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12 December 2020

Consistent genetic alterations in xenografts of proximal stomach and gastro-esophageal junction adenocarcinomas

1 reference

12 December 2020

Optimization of comparative genomic hybridization using fluorochrome conjugated to dCTP and dUTP nucleotides

1 reference

12 December 2020

Changes in DNA copy number in primary gastric carcinomas by comparative genomic hybridization

1 reference

12 December 2020

Comparative genomic hybridization as a tool to define two distinct chromosome 12-derived amplification units in well-differentiated liposarcomas

1 reference

12 December 2020

The human CAS (cellular apoptosis susceptibility) gene mapping on chromosome 20q13 is amplified in BT474 breast cancer cells and part of aberrant chromosomes in breast and colon cancer cell lines

1 reference

12 December 2020

Mapping of chromosomal gains and losses in primitive neuroectodermal tumors by comparative genomic hybridization

1 reference

12 December 2020

Gains and losses of DNA sequences in liposarcomas evaluated by comparative genomic hybridization

1 reference

12 December 2020

Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghausen's neurofibromatosis

1 reference

12 December 2020

Overrepresentation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer

1 reference

12 December 2020

Novel formation and amplification of the PAX7-FKHR fusion gene in a case of alveolar rhabdomyosarcoma

1 reference

12 December 2020

Detection of chromosomal DNA gains and losses in testicular germ cell tumors by comparative genomic hybridization

1 reference

12 December 2020

Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas

1 reference

12 December 2020

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

1 reference

12 December 2020

Gene amplification of c-myc and N-myc in small cell carcinoma of the lung

1 reference

12 December 2020

Expression of calcyclin in human melanoma cell lines correlates with metastatic behavior in nude mice

1 reference

12 December 2020

SAS amplification in soft tissue sarcomas

1 reference

12 December 2020

Differential regulation of mRNAs encoding three protein-tyrosine phosphatases by insulin and activation of protein kinase C

1 reference

12 December 2020

MDM2 gene amplification in metastatic osteosarcoma

1 reference

12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

1 reference

12 December 2020

Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein expression

1 reference

12 December 2020

Extrachromosomal gene amplification in acute myeloid leukemia; Characterization by metaphase analysis, comparative genomic hybridization, and semi-quantitative PCR

1 reference

12 December 2020

Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization

1 reference

12 December 2020

Chromosomal gains and losses in uveal melanomas detected by comparative genomic hybridization

1 reference

12 December 2020

MDM2 gene amplification correlates with ring chromosome in soft tissue tumors

1 reference

12 December 2020

Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q

1 reference

12 December 2020

Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Tampere CLL Group

1 reference

12 December 2020

Comparative genomic hybridization analysis of Wilms tumors

1 reference

12 December 2020

17q12-21 amplicon, a novel recurrent genetic change in intestinal type of gastric carcinoma: A comparative genomic hybridization study

1 reference

12 December 2020

Frequent gains on chromosome arms 1q and/or 8q in human endometrial cancer

1 reference

12 December 2020

Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization

1 reference

12 December 2020

Amplification of chromosome subregion 12p11.2-p12.1 in a metastasis of an i(12p)-negative seminoma: relationship to tumor progression?

1 reference

12 December 2020

Comparative genomic hybridization detects novel deletions and amplifications in head and neck squamous cell carcinomas

1 reference

12 December 2020

Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization

1 reference

12 December 2020

Comparative genomic hybridization study of primary neuroblastoma tumors. United Kingdom Children's Cancer Study Group

1 reference

12 December 2020

Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations

1 reference

12 December 2020

Comparative genomic hybridization detects genomic abnormalities in 80% of follicular lymphomas

1 reference

12 December 2020

Genetic aberrations in pediatric acute lymphoblastic leukemia by comparative genomic hybridization

1 reference

12 December 2020

DNA copy number losses in chromosome 14: an early change in gastrointestinal stromal tumors

1 reference

12 December 2020

Identification of gains and losses of DNA sequences in primary bladder cancer by comparative genomic hybridization

1 reference

12 December 2020

Comparative genomic hybridization in chronic B-cell leukemias shows a high incidence of chromosomal gains and losses

1 reference

12 December 2020

Characterization of the 12q13-15 amplicon in soft tissue tumors

1 reference

12 December 2020

Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas

1 reference

12 December 2020

Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas

1 reference

12 December 2020

REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma

1 reference

12 December 2020

Mapping of chromosomal gains and losses in prostate cancer by comparative genomic hybridization

1 reference

12 December 2020

Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene

1 reference

12 December 2020

DNA copy number changes in diffuse large B-cell lymphoma--comparative genomic hybridization study

1 reference

12 December 2020

Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas

1 reference

12 December 2020

Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

1 reference

12 December 2020

Complexity of 12q13-22 amplicon in liposarcoma: microsatellite repeat analysis

1 reference

12 December 2020

Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization

1 reference

12 December 2020

Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer

1 reference

12 December 2020

Comparative genomic hybridization analysis detects frequent, often high-level, overrepresentation of DNA sequences at 3q, 5p, 7p, and 8q in human non-small cell lung carcinomas

1 reference

12 December 2020

Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung

1 reference

12 December 2020

Comparative genomic hybridization (CGH) analysis of neuroblastomas--an important methodological approach in paediatric tumour pathology

1 reference

12 December 2020

Chromosomal breakpoints and changes in DNA copy number in refractory acute myeloid leukemia

1 reference

12 December 2020

Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma

1 reference

12 December 2020

BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma

1 reference

12 December 2020

No DNA copy number changes in osteochondromas: A comparative genomic hybridization study

1 reference

12 December 2020

Mapping of chromosomal imbalances in pancreatic carcinoma by comparative genomic hybridization

1 reference

12 December 2020

Identification of novel regions of deletion in familial Wilms' tumor by comparative genomic hybridization

1 reference

12 December 2020

High incidence of chromosomal imbalances and gene amplifications in the classical follicular variant of follicle center lymphoma

1 reference

12 December 2020

MDM2 amplification in a primary alveolar rhabdomyosarcoma displaying a t(2;13)(q35;q14)

1 reference

12 December 2020

Identifiers

PMC publication ID

1858578

1 reference

10 August 2017

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