Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. (Q35558693)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22006328%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice (English)

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autosomal dominant hypophosphatemic rickets

14 January 2020

main subject

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1 reference

2

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James C Fleet

5

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14 January 2020

Matthew R. Allen

6

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15

Siu L Hui

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author name string

Emily G Farrow

1

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14 January 2020

Lelia J Summers

3

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14 January 2020

Siobhan I Davis

4

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14 January 2020

Alexander G Robling

7

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Keith R Stayrook

8

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Victoria Jideonwo

9

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Martin J Magers

10

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14 January 2020

Holly J Garringer

11

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Ruben Vidal

12

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Rebecca J Chan

13

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14 January 2020

Charles B Goodwin

14

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Munro Peacock

16

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Kenneth E White

17

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14 January 2020

language of work or name

English

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publication date

17 October 2011

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Proceedings of the National Academy of Sciences of the United States of America

14 January 2020

published in

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volume

108

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page(s)

E1146-55

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issue

46

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Iron modifies plasma FGF23 differently in autosomal dominant hypophosphatemic rickets and healthy humans

14 January 2020

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1 reference

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Altered renal FGF23-mediated activity involving MAPK and Wnt: effects of the Hyp mutation

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Diagnosis and treatment of iron-deficiency anaemia during pregnancy and postpartum

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Morphological assessment of basic multicellular unit resorption parameters in dogs shows additional mechanisms of bisphosphonate effects on bone

12 July 2018

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An autosomal dominant hypophosphatemic rickets phenotype in a Tunisian family caused by a new FGF23 missense mutation

12 July 2018

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Initial FGF23-mediated signaling occurs in the distal convoluted tubule

12 July 2018

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Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

12 July 2018

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FGF23 concentrations vary with disease status in autosomal dominant hypophosphatemic rickets.

12 July 2018

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Klotho converts canonical FGF receptor into a specific receptor for FGF23

12 July 2018

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Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism.

12 July 2018

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12 July 2018

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Regulation of phosphorus homeostasis by the type iia na/phosphate cotransporter

12 July 2018

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Fibroblast growth factor-23 mutants causing familial tumoral calcinosis are differentially processed.

12 July 2018

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Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice

12 July 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

12 July 2018

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FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

12 July 2018

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Activation of the hypoxia‐inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors

12 July 2018

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Involvement of p38 MAP kinase during iron chelator-mediated apoptotic cell death

12 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

12 July 2018

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Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23

12 July 2018

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Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

12 July 2018

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Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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FGF23 elevation and hypophosphatemia after intravenous iron polymaltose: a prospective study

12 July 2018

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26 September 2018

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DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis.

26 September 2018

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26 September 2018

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Iron loading into ferritin can be stimulated or inhibited by the presence of cations and anions: a specific role for phosphate.

26 September 2018

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Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis

26 September 2018

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26 September 2018

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Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia

26 September 2018

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Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia

26 September 2018

1 reference

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Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.

26 September 2018

1 reference

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Saccharated ferric oxide-induced osteomalacia in Japan: iron-induced osteopathy due to nephropathy.

26 September 2018

1 reference

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Effects of dietary iron deficiency on muscle fiber characteristics and whole-body distribution of hemoglobin in mice.

26 September 2018

1 reference

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Relation between hypomineralized periosteocytic lesions and bone mineralization in vitamin D-resistant rickets

26 September 2018

1 reference

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Familial hypophosphatemic rickets showing autosomal dominant inheritance

26 September 2018

1 reference

12 December 2020

Autosomal dominant hypophosphatemic rickets/osteomalacia: clinical characterization of a novel renal phosphate-wasting disorder

1 reference

12 December 2020

Saccharated ferric oxide (SFO)-induced osteomalacia: in vitro inhibition by SFO of bone formation and 1,25-dihydroxy-vitamin D production in renal tubules

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12 December 2020

Iron polymaltose-induced FGF23 elevation complicated by hypophosphataemic osteomalacia

1 reference

12 December 2020

Hypophosphatemia induced by intravenous administration of saccharated ferric oxide: another form of FGF23-related hypophosphatemia

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12 December 2020

The effects of dietary ferric iron and iron deprivation on the bacterial composition of the mouse intestine

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1110905108

1 reference

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14 January 2020

0 references

1 reference

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14 January 2020

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