Organization and dynamics of the Mu transpososome: recombination by communication between two active sites (Q35208441)

7 August 2017

title

Organization and dynamics of the Mu transpososome: recombination by communication between two active sites (English)

1 reference

7 August 2017

T L Williams

1

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7 August 2017

E L Jackson

series ordinal

2

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7 August 2017

A Carritte

series ordinal

3

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7 August 2017

T A Baker

series ordinal

4

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7 August 2017

publication date

1 October 1999

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7 August 2017

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7 August 2017

volume

13

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7 August 2017

issue

20

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7 August 2017

page(s)

2725-2737

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describes a project that uses

7 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC317111/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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13 July 2018

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Three new structures of the core domain of HIV-1 integrase: An active site that binds magnesium

13 July 2018

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The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition

13 July 2018

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Mutational analysis of domain II beta of bacteriophage Mu transposase: domains II alpha and II beta belong to different catalytic complementation groups

13 July 2018

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Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains.

13 July 2018

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A new set of Mu DNA transposition intermediates: alternate pathways of target capture preceding strand transfer

13 July 2018

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13 July 2018

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The Tn7 transposase is a heteromeric complex in which DNA breakage and joining activities are distributed between different gene products.

13 July 2018

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Positional information within the Mu transposase tetramer: catalytic contributions of individual monomers

13 July 2018

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13 July 2018

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Characterization of a region in phage Mu transposase that is involved in interaction with the Mu B protein.

13 July 2018

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Identification of residues in the Mu transposase essential for catalysis

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A domain sharing model for active site assembly within the Mu A tetramer during transposition: the enhancer may specify domain contributions.

13 July 2018

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13 July 2018

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The two single-strand cleavages at each end of Tn10 occur in a specific order during transposition

13 July 2018

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A novel DNA binding and nuclease activity in domain III of Mu transposase: evidence for a catalytic region involved in donor cleavage

13 July 2018

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Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration

13 July 2018

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13 July 2018

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Structural domains in phage Mu transposase: identification of the site-specific DNA-binding domain

13 July 2018

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A truncated form of the bacteriophage Mu B protein promotes conservative integration, but not replicative transposition, of Mu DNA.

13 July 2018

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Interaction of distinct domains in Mu transposase with Mu DNA ends and an internal transpositional enhancer.

13 July 2018

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Stimulation of the Mu A protein-mediated strand cleavage reaction by the Mu B protein, and the requirement of DNA nicking for stable type 1 transpososome formation. In vitro transposition characteristics of mini-Mu plasmids carrying terminal base pa

13 July 2018

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Transposase contacts with mu DNA ends

13 July 2018

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DNase protection analysis of the stable synaptic complexes involved in Mu transposition

13 July 2018

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Structural aspects of a higher order nucleoprotein complex: induction of an altered DNA structure at the Mu-host junction of the Mu type 1 transpososome

13 July 2018

1 reference

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Tn7 transposition in vitro proceeds through an excised transposon intermediate generated by staggered breaks in DNA.

13 July 2018

1 reference

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Two mutations of phage mu transposase that affect strand transfer or interactions with B protein lie in distinct polypeptide domains

13 July 2018

1 reference

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A mutation at one end of Moloney murine leukemia virus DNA blocks cleavage of both ends by the viral integrase in vivo

13 July 2018

1 reference

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Mutational analysis of the integrase protein of human immunodeficiency virus type 2

13 July 2018

1 reference

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Identification of conserved amino acid residues critical for human immunodeficiency virus type 1 integrase function in vitro

13 July 2018

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Transpositional recombination: mechanistic insights from studies of mu and other elements

13 July 2018

1 reference

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Excision of Tn10 from the donor site during transposition occurs by flush double-strand cleavages at the transposon termini

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317111

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

13 July 2018

1 reference

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P element transposition in vitro proceeds by a cut-and-paste mechanism and uses GTP as a cofactor.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317111

The Tn10 synaptic complex can capture a target DNA only after transposon excision

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317111

Disruption of the terminal base pairs of retroviral DNA during integration

26 September 2018

1 reference

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Abnormal cointegrate structures mediated by gene B mutants of phage Mu: their implications with regard to gene function

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317111

Mutations in domain IIIα of the mu transposase: evidence suggesting an active site component which interacts with the Mu-Host junction 1 1Edited by M. Gottesman

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317111

MuB protein allosterically activates strand transfer by the transposase of phage Mu

15 November 2018

1 reference

12 December 2020

Assembly of the active form of the transposase-Mu DNA complex: a critical control point in Mu transposition

1 reference

12 December 2020

Division of labor among monomers within the Mu transposase tetramer

1 reference

12 December 2020

Complete transposition requires four active monomers in the mu transposase tetramer

1 reference

12 December 2020

Step-arrest mutants of phage Mu transposase. Implications in DNA-protein assembly, Mu end cleavage, and strand transfer

1 reference

12 December 2020

Enhanced and coordinated processing of synapsed viral DNA ends by retroviral integrases in vitro

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12 December 2020

Assembly of phage Mu transpososomes: cooperative transitions assisted by protein and DNA scaffolds

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12 December 2020

The three chemical steps of Tn10/IS10 transposition involve repeated utilization of a single active site

1 reference

12 December 2020

The interwoven architecture of the Mu transposase couples DNA synapsis to catalysis

1 reference

12 December 2020

Mu transpositional recombination: donor DNA cleavage and strand transfer in trans by the Mu transposase

1 reference

12 December 2020

Mutational analysis of the Mu transposase. Contributions of two distinct regions of domain II to recombination

1 reference

12 December 2020

Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA

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12 December 2020

Identifiers

DOI

10.1101/GAD.13.20.2725

1 reference

7 August 2017

1 reference

7 August 2017

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