Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression (Q35202114)

7 August 2017

title

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression (English)

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7 August 2017

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6

W G Kaelin

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7 August 2017

R C O'Hagan

1

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7 August 2017

M Ohh

2

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7 August 2017

G David

3

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7 August 2017

I M de Alboran

4

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7 August 2017

F W Alt

5

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7 August 2017

R A DePinho

7

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7 August 2017

publication date

1 September 2000

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7 August 2017

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7 August 2017

volume

14

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7 August 2017

issue

17

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7 August 2017

page(s)

2185-2191

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A genetic screen to identify genes that rescue the slow growth phenotype of c-myc null fibroblasts

7 August 2017

cites work

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13 July 2018

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

13 July 2018

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

13 July 2018

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c-Myc enhances protein synthesis and cell size during B lymphocyte development

13 July 2018

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Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

13 July 2018

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Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

13 July 2018

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Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

13 July 2018

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13 July 2018

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

13 July 2018

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c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

13 July 2018

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13 July 2018

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The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

13 July 2018

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13 July 2018

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C-Myc Transrepression and Cell Transformation

13 July 2018

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Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

13 July 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

13 July 2018

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Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

13 July 2018

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Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

13 July 2018

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Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc

13 July 2018

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Cdc25 cell-cycle phosphatase as a target of c-myc

13 July 2018

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cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

13 July 2018

1 reference

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Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis

13 July 2018

1 reference

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Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1

13 July 2018

1 reference

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c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

Participation of cyclin A in Myc-induced apoptosis.

13 July 2018

1 reference

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Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

13 July 2018

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Sequence-specific DNA binding by the c-Myc protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

The MYC protein activates transcription of the alpha-prothymosin gene.

13 July 2018

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Drosophila myc regulates cellular growth during development

13 July 2018

1 reference

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The role of protein stability in the cell cycle and cancer

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

Repression of c-Myc responsive genes in cycling cells causes G1 arrest through reduction of cyclin E/CDK2 kinase activity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

Regulation of cell cycle duration by c-myc levels.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316894

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

26 September 2018

1 reference

12 December 2020

Kip1 meets SKP2: new links in cell-cycle control

1 reference

12 December 2020

A quantitative cytochemical investigation of the relationship between cell mass and initiation of DNA synthesis in mouse fibroblasts in vitro

1 reference

12 December 2020

Cancer prognostics: past, present and p27

1 reference

12 December 2020

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

12 December 2020

p27 expression and gastric carcinoma

1 reference

12 December 2020

Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.827200

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7 August 2017

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7 August 2017

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