When ubiquitin meets ubiquitin receptors: a signalling connection (Q35141760)

6 August 2017

title

When ubiquitin meets ubiquitin receptors: a signalling connection (English)

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6 August 2017

Pier Paolo Di Fiore

1

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6 August 2017

Simona Polo

series ordinal

2

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6 August 2017

Kay Hofmann

series ordinal

3

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6 August 2017

publication date

1 June 2003

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Nature Reviews Molecular Cell Biology

6 August 2017

language of work or name

English

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published in

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6 August 2017

volume

4

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6 August 2017

issue

6

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6 August 2017

page(s)

491-497

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publication type of scholarly work

6 August 2017

review article

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

31 March 2020

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Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

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Protein regulation by monoubiquitin

31 March 2020

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The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

31 March 2020

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From UBA to UBX: new words in the ubiquitin vocabulary.

31 March 2020

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Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

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The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly

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Recognition of specific ubiquitin conjugates is important for the proteolytic functions of the ubiquitin-associated domain proteins Dsk2 and Rad23.

31 March 2020

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UBA domains of DNA damage-inducible proteins interact with ubiquitin

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Structure of a human DNA repair protein UBA domain that interacts with HIV-1 Vpr.

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Solution structures of UBA domains reveal a conserved hydrophobic surface for protein-protein interactions

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A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

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A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

31 March 2020

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The Vps27p Hse1p complex binds ubiquitin and mediates endosomal protein sorting.

31 March 2020

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Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

31 March 2020

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Ligand-independent degradation of epidermal growth factor receptor involves receptor ubiquitylation and Hgs, an adaptor whose ubiquitin-interacting motif targets ubiquitylation by Nedd4.

31 March 2020

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The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination

31 March 2020

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A ubiquitin-interacting motif from Hrs binds to and occludes the ubiquitin surface necessary for polyubiquitination in monoubiquitinated proteins

31 March 2020

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Identification of homer as a homologue of the Wiskott-Aldrich syndrome protein suggests a receptor-binding function for WH1 domains

31 March 2020

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Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

31 March 2020

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RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

31 March 2020

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Structure and functional interactions of the Tsg101 UEV domain

31 March 2020

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Ubiquitin signals protein trafficking via interaction with a novel ubiquitin binding domain in the membrane fusion regulator, Vps9p

31 March 2020

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A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain

31 March 2020

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Signaling--2000 and beyond

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PhosphoSerine/threonine binding domains: you can't pSERious?

31 March 2020

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Epidermal growth factor induces ubiquitination of Eps15.

31 March 2020

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Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors

31 March 2020

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

31 March 2020

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Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

31 March 2020

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mGrb10 interacts with Nedd4

31 March 2020

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Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

31 March 2020

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Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

31 March 2020

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The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC

31 March 2020

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S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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Receptor downregulation and multivesicular-body sorting

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Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

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A new ticket for entry into budding vesicles-ubiquitin

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A Function for Monoubiquitination in the Internalization of a G Protein–Coupled Receptor

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

31 March 2020

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The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

31 March 2020

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The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

31 March 2020

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Multiple roles for Rsp5p-dependent ubiquitination at the internalization step of endocytosis

31 March 2020

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Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

31 March 2020

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Monoubiquitin carries a novel internalization signal that is appended to activated receptors

31 March 2020

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

31 March 2020

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Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

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A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

31 March 2020

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A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination

31 March 2020

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Solution structure of a Nedd4 WW domain-ENaC peptide complex

31 March 2020

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Ubiquitin-dependent protein degradation

31 March 2020

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Positional cloning of a novel Fanconi anemia gene, FANCD2

31 March 2020

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Biallelic inactivation of BRCA2 in Fanconi anemia

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Vps9p is a guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport

31 March 2020

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A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function

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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1124

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6 August 2017

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