Considering the cancer consequences of altered DNA polymerase function (Q35079299)

6 August 2017

title

Considering the cancer consequences of altered DNA polymerase function (English)

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6 August 2017

Thomas A Kunkel

1

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6 August 2017

publication date

1 February 2003

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6 August 2017

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6 August 2017

volume

3

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6 August 2017

issue

2

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6 August 2017

page(s)

105-110

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publication type of scholarly work

6 August 2017

review article

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Streisinger revisited: DNA synthesis errors mediated by substrate misalignments

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7 January 2021

Structure-based interpretation of missense mutations in Y-family DNA polymerases and their implications for polymerase function and lesion bypass

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7 January 2021

Lesion bypass in yeast cells: Pol eta participates in a multi-DNA polymerase process

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Evidence that replication fork components catalyze establishment of cohesion between sister chromatids

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An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA

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The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool

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Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants

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7 January 2021

Error-prone DNA polymerases: novel structures and the benefits of infidelity

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Specialized DNA polymerases, cellular survival, and the genesis of mutations

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High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading

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Error-prone repair DNA polymerases in prokaryotes and eukaryotes

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RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

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7 January 2021

Eukaryotic DNA Polymerases

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The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

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Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

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Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.

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Active site tightness and substrate fit in DNA replication

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7 January 2021

DNA replication fidelity

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7 January 2021

Functions of human DNA polymerases eta, kappa and iota suggested by their properties, including fidelity with undamaged DNA templates.

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Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p

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Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication

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7 January 2021

Multiple mutations and cancer

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Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

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7 January 2021

Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair

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7 January 2021

Functions of p53 suppress critical consequences of damage and repair in the initiation of cancer

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7 January 2021

A physical and functional interaction between yeast Pol4 and Dnl4-Lif1 links DNA synthesis and ligation in nonhomologous end joining

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7 January 2021

Evolution of the two-step model for UV-mutagenesis

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Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals

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7 January 2021

10.1016/S1535-6108(03)00027-8

Identifiers

DOI

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6 August 2017

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