Aptamers as tools for target prioritization and lead identification (Q35053220)

6 August 2017

title

Aptamers as tools for target prioritization and lead identification (English)

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6 August 2017

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Petra Burgstaller

1

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6 August 2017

Anne Girod

series ordinal

2

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6 August 2017

Michael Blind

series ordinal

3

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6 August 2017

publication date

1 December 2002

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6 August 2017

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6 August 2017

volume

7

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6 August 2017

issue

24

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6 August 2017

page(s)

1221-1228

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publication type of scholarly work

6 August 2017

review article

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Transgenic gene knock-outs: functional genomics and therapeutic target selection

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7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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RNA interference--2001.

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RNA interference is mediated by 21- and 22-nucleotide RNAs

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Adaptive recognition by nucleic acid aptamers

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Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

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In vitro selection of RNA molecules that bind specific ligands

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7 January 2021

Nucleic acid aptamers-from selection in vitro to applications in vivo

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7 January 2021

HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity

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7 January 2021

Potent 2'-amino-, and 2'-fluoro-2'-deoxyribonucleotide RNA inhibitors of keratinocyte growth factor

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7 January 2021

2'-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

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7 January 2021

Developing aptamers into therapeutics

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7 January 2021

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7 January 2021

In vitro selection of nucleic acid aptamers that bind proteins

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7 January 2021

In vitro selection of RNA aptamers

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7 January 2021

Automated RNA selection

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7 January 2021

Automated selection of anti-protein aptamers

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7 January 2021

RNA Molecules That Bind to and Inhibit the Active Site of a Tyrosine Phosphatase

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7 January 2021

DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity

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7 January 2021

Intramers as promising new tools in functional proteomics

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7 January 2021

GnRH binding RNA and DNA Spiegelmers: a novel approach toward GnRH antagonism

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In vivo properties of an anti-GnRH Spiegelmer: an example of an oligonucleotide-based therapeutic substance class

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7 January 2021

Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys

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7 January 2021

Vascular permeability factor: A unique regulator of blood vessel function

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7 January 2021

The emerging concept of vascular remodeling

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7 January 2021

VEGF(165) mediates glomerular endothelial repair

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7 January 2021

Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers.

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7 January 2021

Expression of small, therapeutic RNAs in human cell nuclei.

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7 January 2021

RNA aptamers as effective protein antagonists in a multicellular organism

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7 January 2021

Cytoplasmic RNA modulators of an inside-out signal-transduction cascade

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7 January 2021

Receptor Ligand-Facilitated Cationic Liposome Delivery of Anti-HIV-1 Rev-Binding Aptamer and Ribozyme DNAs

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7 January 2021

Rev-binding aptamer and CMV promoter act as decoys to inhibit HIV replication

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7 January 2021

A novel RNA motif that binds efficiently and specifically to the Ttat protein of HIV and inhibits the trans-activation by Tat of transcription in vitro and in vivo

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7 January 2021

Anti-idiotype RNAs that mimic the leucine-rich nuclear export signal and specifically bind to CRM1/exportin 1

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7 January 2021

Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers

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7 January 2021

Integrins and inside-out signal transduction: converging signals from PKC and PIP3

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7 January 2021

A specific RNA hairpin loop structure binds the RNA recognition motifs of the Drosophila SR protein B52

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7 January 2021

Aptamers as reagents for high-throughput screening

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7 January 2021

Bringing picomolar protein detection into proximity

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7 January 2021

An enzyme-linked oligonucleotide assay

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7 January 2021

In vitro selection of signaling aptamers

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7 January 2021

Aptamer beacons for the direct detection of proteins

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7 January 2021

Engineered allosteric ribozymes as biosensor components

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7 January 2021

Rational design of allosteric ribozymes

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7 January 2021

Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology

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7 January 2021

Inhibitory DNA ligands to platelet-derived growth factor B-chain

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7 January 2021

HIV-1 rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA

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7 January 2021

10.1016/S1359-6446(02)02522-9

Identifiers

DOI

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6 August 2017

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