Inhibition of the human ether-a-go-go-related gene (HERG) potassium channel by cisapride: affinity for open and inactivated states. (Q35041505)

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31 October 2019

title

Inhibition of the human ether-a-go-go-related gene (HERG) potassium channel by cisapride: affinity for open and inactivated states (English)

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31 October 2019

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5

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31 October 2019

author name string

B D Walker

1

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31 October 2019

C B Singleton

2

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31 October 2019

J A Bursill

3

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31 October 2019

K R Wyse

4

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M R Qiu

6

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S N Breit

7

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T J Campbell

8

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31 October 2019

publication date

1 September 1999

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British Journal of Pharmacology

31 October 2019

language of work or name

English

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published in

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volume

128

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issue

2

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page(s)

444-450

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Cardiac Arrest Associated With Combination Cisapride and Itraconazole Therapy

31 October 2019

cites work

1 reference

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Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate

8 July 2018

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A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG

8 July 2018

1 reference

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Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride

8 July 2018

1 reference

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A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes

8 July 2018

1 reference

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A minK-HERG complex regulates the cardiac potassium current I(Kr)

8 July 2018

1 reference

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Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro: implications for proarrhythmic potential?

8 July 2018

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Effects of 5-HT4-receptor agonists, cisapride, mosapride citrate, and zacopride, on cardiac action potentials in guinea pig isolated papillary muscles

8 July 2018

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The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

8 July 2018

1 reference

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Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide

8 July 2018

1 reference

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HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine

8 July 2018

1 reference

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Fast inactivation causes rectification of the IKr channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

High affinity open channel block by dofetilide of HERG expressed in a human cell line.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

The inward rectification mechanism of the HERG cardiac potassium channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

Long QT Syndrome During High-Dose Cisapride

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1571630

Cisapride. An updated review of its pharmacology and therapeutic efficacy as a prokinetic agent in gastrointestinal motility disorders

8 July 2018

1 reference

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Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents

8 July 2018

1 reference

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An overview of class III electrophysiological agents: a new generation of antiarrhythmic therapy

8 July 2018

1 reference

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Normalization of acquired QT prolongation in humans by intravenous potassium

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702774

Block of the Rapid Component of the Delayed Rectifier Potassium Current by the Prokinetic Agent Cisapride Underlies Drug-Related Lengthening of the QT Interval

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702774

Cisapride-induced prolongation of cardiac action potential and early afterdepolarizations in rabbit Purkinje fibres.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702774

Antiarrhythmic drugs and cardiac ion channels: mechanisms of action

21 January 2018

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Modulation of HERG affinity for E-4031 by [K+]o and C-type inactivation

25 October 2018

1 reference

12 December 2020

Cisapride and fatal arrhythmia

1 reference

12 December 2020

Modulation of the Electrophysiologic Actions of E-4031 and Dofetilide by Hyperkalemia and Acidosis in Rabbit Ventricular Myocytes

1 reference

12 December 2020

Extracellular potassium modulation of drug block of IKr. Implications for torsade de pointes and reverse use-dependence

1 reference

12 December 2020

Secretion of the gastrokinetic agent cisapride in human milk

1 reference

12 December 2020

Vesnarinone Prolongs Action Potential Duration Without Reverse Frequency Dependence in Rabbit Ventricular Muscle by Blocking the Delayed Rectifier K + Current

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0702774

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10510456%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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31 October 2019

PubMed publication ID

10510456

1 reference