C-C motif chemokine ligand 5 (Q3492926)

C-C motif chemokine 5

1 reference

Chemokine interleukin-8-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CC chemokine, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

receptor signaling protein tyrosine kinase activator activity

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemokine activity

Platelets Secrete an Eosinophil-Chemotactic Cytokine which is a Member of the C-C-Chemokine Family

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

16 July 2018

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

protein self-association

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

phosphatidylinositol phospholipase C activity

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

protein kinase activity

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cytokine activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

1 reference

8 April 2019

CCR1 chemokine receptor binding

RANTES and MIP-1α Activate Stats in T Cells

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

phospholipase activator activity

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemokine receptor binding

2 references

8 April 2019

Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Functional and biochemical analysis of the cloned Duffy antigen: identity with the red blood cell chemokine receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

protein homodimerization activity

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemokine receptor antagonist activity

1 reference

8 April 2019

RANTES and MCP-3 antagonists bind multiple chemokine receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

protein binding

3 references

8 April 2019

Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemoattractant activity

1 reference

8 April 2019

Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

identical protein binding

4 references

8 April 2019

NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemokine activity

Platelets Secrete an Eosinophil-Chemotactic Cytokine which is a Member of the C-C-Chemokine Family

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

8 April 2019

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

CCR chemokine receptor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cell component

cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

extracellular region

extracellular space

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

leukocyte cell-cell adhesion

biological process

1 reference

8 April 2019

Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of cell-cell adhesion mediated by integrin

1 reference

8 April 2019

Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

regulation of T cell activation

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of smooth muscle cell migration

1 reference

8 April 2019

Bronchial Epithelium–Derived IL-8 and RANTES Increased Bronchial Smooth Muscle Cell Migration and Proliferation by Krüppel-like Factor 5 in Areca Nut–Mediated Airway Remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

activation of phospholipase D activity

1 reference

8 April 2019

RANTES activation of phospholipase D in Jurkat T cells: requirement of GTP-binding proteins ARF and RhoA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

negative regulation of viral genome replication

1 reference

8 April 2019

TNF-alpha inhibits HIV-1 replication in peripheral blood monocytes and alveolar macrophages by inducing the production of RANTES and decreasing C-C chemokine receptor 5 (CCR5) expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of innate immune response

1 reference

8 April 2019

TLR2-dependent pathway of heterologous down-modulation for the CC chemokine receptors 1, 2, and 5 in human blood monocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular response to interferon-gamma

1 reference

16 July 2018

Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

positive regulation of macrophage chemotaxis

1 reference

8 April 2019

CCR5 usage by CCL5 induces a selective leukocyte recruitment in human skin xenografts in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

calcium ion transport

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

exocytosis

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of calcium ion transport

1 reference

8 April 2019

Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

response to cytokine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

regulation of insulin secretion

1 reference

8 April 2019

The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemokine-mediated signaling pathway

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

16 July 2018

RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

positive regulation of cellular biosynthetic process

1 reference

8 April 2019

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of monocyte chemotaxis

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular response to fibroblast growth factor stimulus

1 reference

8 April 2019

Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

neutrophil chemotaxis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

response to tumor necrosis factor

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

negative regulation of T cell apoptotic process

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of GTPase activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

negative regulation of macrophage apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of T cell proliferation

1 reference

8 April 2019

XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of phosphorylation

1 reference

8 April 2019

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

positive regulation of translational initiation

NAS

1 reference

8 April 2019

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

response to toxic substance

NAS

1 reference

8 April 2019

In vitro correlates of HIV-2-mediated HIV-1 protection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of epithelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

8 April 2019

RANTES and MIP-1α Activate Stats in T Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular response to organic cyclic compound

1 reference

8 April 2019

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular calcium ion homeostasis

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

protein tetramerization

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of homotypic cell-cell adhesion

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular response to interleukin-1

1 reference

16 July 2018

Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

1 reference

8 April 2019

positive regulation of viral genome replication

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of receptor signaling pathway via JAK-STAT

1 reference

8 April 2019

Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

lipopolysaccharide-mediated signaling pathway

1 reference

8 April 2019

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of T cell migration

1 reference

8 April 2019

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

regulation of chronic inflammatory response

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of smooth muscle cell proliferation

1 reference

8 April 2019

Bronchial Epithelium–Derived IL-8 and RANTES Increased Bronchial Smooth Muscle Cell Migration and Proliferation by Krüppel-like Factor 5 in Areca Nut–Mediated Airway Remodeling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

neutrophil activation

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

protein kinase B signaling

1 reference

8 April 2019

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of cell migration

1 reference

8 April 2019

Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of natural killer cell chemotaxis

1 reference

8 April 2019

Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cell-cell signaling

1 reference

8 April 2019

Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

eosinophil chemotaxis

1 reference

8 April 2019

CCR5 usage by CCL5 induces a selective leukocyte recruitment in human skin xenografts in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

dendritic cell chemotaxis

1 reference

8 April 2019

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

MAPK cascade

1 reference

8 April 2019

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

macrophage chemotaxis

1 reference

8 April 2019

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of T cell chemotaxis

4 references

16 July 2018

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

CCR5 usage by CCL5 induces a selective leukocyte recruitment in human skin xenografts in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

regulation of neuron death

1 reference

8 April 2019

RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

negative regulation of G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of T cell apoptotic process

1 reference

8 April 2019

Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of cell adhesion

1 reference

8 April 2019

LEC induces chemotaxis and adhesion by interacting with CCR1 and CCR8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

negative regulation of chemokine-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

monocyte chemotaxis

IC

1 reference

16 July 2018

Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

IC

positive chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of protein tyrosine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular response to tumor necrosis factor

1 reference

16 July 2018

Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

positive regulation of activation of Janus kinase activity

1 reference

8 April 2019

Rantes activates Jak2 and Jak3 to regulate engagement of multiple signaling pathways in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

regulation of signaling receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

3 references

16 July 2018

16 July 2018

The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

16 July 2018

RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13501&geneProductId=UniProtKB:P13501

cytokine-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

1 reference

8 April 2019

monocyte chemotaxis

IC

inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

4 references

8 April 2019

8 April 2019

The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

positive regulation of T cell chemotaxis

CCR5 usage by CCL5 induces a selective leukocyte recruitment in human skin xenografts in vivo

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

lymphocyte chemotaxis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

chemokine-mediated signaling pathway

CCL5-mediated T-cell chemotaxis involves the initiation of mRNA translation through mTOR/4E-BP1

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

8 April 2019

RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13501

cellular response to interferon-gamma

cellular response to interleukin-1

cellular response to tumor necrosis factor

positive regulation of monocyte chemotaxis

CC chemokine, conserved site

Gene Atlas image

PBB GE CCL5 1405 i at fs.png
732 × 530; 10 KB

0 references

has part(s)

1 reference

Chemokine interleukin-8-like domain

1 reference

D12.644.276.374.200.110.250

Identifiers

MeSH descriptor ID

D018946

subject named as

Chemokine CCL5

0 references

MeSH tree code

broader concept

CC chemokine

0 references

D12.776.467.374.200.110.250

0 references

0 references

0 references

D23.529.374.200.110.250

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID (discontinued)

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference

UMLS 2023