Prospects for cationic polymers in gene and oligonucleotide therapy against cancer (Q34804863)

4 August 2017

title

Prospects for cationic polymers in gene and oligonucleotide therapy against cancer (English)

1 reference

4 August 2017

3

Thomas Kissel

1 reference

4 August 2017

Thomas Merdan

1

1 reference

4 August 2017

Jindrich Kopecek

series ordinal

2

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4 August 2017

publication date

1 September 2002

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Advanced Drug Delivery Reviews

4 August 2017

language of work or name

English

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published in

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4 August 2017

volume

54

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4 August 2017

issue

5

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4 August 2017

page(s)

715-758

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publication type of scholarly work

4 August 2017

review article

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Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53.

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The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

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A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity

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Transfer of YACs up to 2.3 Mb intact into human cells with polyethylenimine

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Transfection of large plasmids in primary human myoblasts.

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

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Efficient Gene Transfer Using Reversibly Cross-Linked Low Molecular Weight Polyethylenimine

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ExGen 500 is an efficient vector for gene delivery to lung epithelial cells in vitro and in vivo

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In vivo delivery to tumors of DNA complexed with linear polyethylenimine.

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7 January 2021

Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo

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7 January 2021

Overcoming the nuclear barrier: cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation

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7 January 2021

Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA.

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7 January 2021

Intracellular processing of poly(ethylene imine)/ribozyme complexes can be observed in living cells by using confocal laser scanning microscopy and inhibitor experiments

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7 January 2021

Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

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7 January 2021

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle

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7 January 2021

Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells

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7 January 2021

pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer

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7 January 2021

Efficient gene transfer by histidylated polylysine/pDNA complexes

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7 January 2021

Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini

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7 January 2021

Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

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7 January 2021

Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

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7 January 2021

In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency

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7 January 2021

Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability

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7 January 2021

In vitro gene delivery by degraded polyamidoamine dendrimers

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7 January 2021

Evaluation of polyplexes as gene transfer agents.

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7 January 2021

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

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7 January 2021

Effect of Albumin and Polyanion on the Structure of DNA Complexes with Polycation Containing Hydrophilic Nonionic Block

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7 January 2021

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

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7 January 2021

Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery

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7 January 2021

The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration

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7 January 2021

Side-effects of a systemic injection of linear polyethylenimine-DNA complexes

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7 January 2021

Polyethylenimine-based intravenous delivery of transgenes to mouse lung.

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7 January 2021

Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse

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7 January 2021

Rapid crossing of the pulmonary endothelial barrier by polyethylenimine/DNA complexes

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7 January 2021

Multiple polyamine transport pathways in cultured pulmonary artery smooth muscle cells: regulation by hypoxia

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7 January 2021

Stabilization of poly-L-lysine/DNA polyplexes for in vivo gene delivery to the liver

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7 January 2021

Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents.

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7 January 2021

Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers.

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7 January 2021

Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application

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7 January 2021

HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action

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7 January 2021

Steric Stabilization of poly-l-Lysine/DNA Complexes by the Covalent Attachment of Semitelechelic poly[N-(2-Hydroxypropyl)methacrylamide]

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7 January 2021

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo

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7 January 2021

Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors

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7 January 2021

Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity

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7 January 2021

Electroporation-enhanced gene delivery in mammary tumors

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7 January 2021

Nonviral Gene Delivery to the Rat Kidney with Polyethylenimine

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7 January 2021

Transgene expression in mouse airway epithelium by aerosol gene therapy with PEI-DNA complexes

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7 January 2021

Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous system

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7 January 2021

Optimisation of polyethylenimine-based gene delivery to mouse brain.

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7 January 2021

Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA complexes

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7 January 2021

A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine

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7 January 2021

Efficient transfer of oligonucleotides and plasmid DNA into the whole heart through the coronary artery

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7 January 2021

Augmentation of myocardial transfection using TerplexDNA: a novel gene delivery system

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7 January 2021

Efficient gene expression in skin wound sites following local plasmid injection

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7 January 2021

Local and distant transfection of mdx muscle fibers with dystrophin and LacZ genes delivered in vivo by synthetic microspheres.

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7 January 2021

Optimization of nonviral gene transfer of vascular smooth muscle cells in vitro and in vivo

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7 January 2021

In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers

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7 January 2021

Effects of linear polyethylenimine and polyethylenimine/DNA on lung function after airway instillation to rat lungs

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7 January 2021

The influence of sodium glycocholate and other additives on the in vivo transfection of plasmid DNA in the lungs

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7 January 2021

Mechanism of lipoplex gene delivery in mouse lung: binding and internalization of fluorescent lipid and DNA components

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7 January 2021

Comparison between intratracheal and intravenous administration of liposome–DNA complexes for cystic fibrosis lung gene therapy

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7 January 2021

Aerosol gene delivery in vivo

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7 January 2021

Aerosolization of cationic lipid-DNA complexes: lipoplex characterization and optimization of aerosol delivery conditions

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7 January 2021

Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI-p53 complexes

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7 January 2021

Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function

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7 January 2021

Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice

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7 January 2021

Noninvasive gene targeting to the brain

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7 January 2021

Role of endocytosis in the transfection of L929 fibroblasts by polyethylenimine/DNA complexes

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7 January 2021

Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery

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7 January 2021

Interaction of polycations with cell-surface negative charges of epithelial cells

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7 January 2021

Evidence for the role of proteoglycans in cation-mediated gene transfer

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7 January 2021

Uptake and intracellular fate of polyethylenimine in vivo

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7 January 2021

Endocytosis and molecular sorting

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7 January 2021

Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein

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7 January 2021

Cellular uptake of the tat protein from human immunodeficiency virus

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7 January 2021

Intercellular trafficking and protein delivery by a herpesvirus structural protein

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7 January 2021

In vivo protein transduction: delivery of a biologically active protein into the mouse

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7 January 2021

Antennapedia homeobox peptide regulates neural morphogenesis

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7 January 2021

Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans

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7 January 2021

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells.

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7 January 2021

Trojan peptides: the penetratin system for intracellular delivery

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7 January 2021

Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

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7 January 2021

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

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7 January 2021

TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors

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7 January 2021

Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

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7 January 2021

Targeted gene transfer for adenocarcinoma using a combination of tumor-specific antibody and tissue-specific promoter

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7 January 2021

Tissue-specific gene therapy directed to tumor angiogenesis.

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7 January 2021

Brain-specific expression of an exogenous gene after i.v. administration

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7 January 2021

Gene therapy: designer promoters for tumour targeting

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7 January 2021

Transfection of folate-polylysine DNA complexes: evidence for lysosomal delivery

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7 January 2021

Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway

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7 January 2021

The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells

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7 January 2021

Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine and its complex with plasmid DNA.

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7 January 2021

Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine)

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7 January 2021

TerplexDNA gene carrier system targeting artery wall cells

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Targeting DNA to cells with basic fibroblast growth factor (FGF2).

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7 January 2021

Different strategies for formation of pegylated EGF-conjugated PEI/DNA complexes for targeted gene delivery

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Synthetic RGD peptides derived from the adhesive domains of snake-venom proteins: evaluation as inhibitors of platelet aggregation

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7 January 2021

Arg-Gly-Asp constrained within cyclic pentapeptides. Strong and selective inhibitors of cell adhesion to vitronectin and laminin fragment P1.

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7 January 2021

Cell delivery, intracellular trafficking and expression of an integrin-mediated gene transfer vector in tracheal epithelial cells

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7 January 2021

Highly efficient transduction of endothelial cells by targeted artificial virus-like particles

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Efficiency of Targeted Gene Delivery of Ligand-Poly-L-Lysine Hybrids with Different Crosslinks

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7 January 2021

Development of transferrin-polycation/DNA based vectors for gene delivery to melanoma cells

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7 January 2021

Polyion complex micelles with protein-modified corona for receptor-mediated delivery of oligonucleotides into cells

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7 January 2021

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides

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7 January 2021

Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses

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7 January 2021

In Vitro Gene Delivery to Hepatocytes with Galactosylated Polyethylenimine

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7 January 2021

Investigation of drug release from suspension using FTIR-ATR technique: part II. Determination of dissolution coefficient of drugs

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7 January 2021

Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-tapgeted gene carrier

1 reference

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7 January 2021

Overexpression of human methylmalonyl CoA mutase in mice after in vivo gene transfer with asialoglycoprotein/polylysine/DNA complexes

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7 January 2021

Targeted delivery of plasmid DNA complexed with galactosylated poly(l-lysine)

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice

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7 January 2021

Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system

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7 January 2021

Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.

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7 January 2021

Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Anti-JL1 antibody-conjugated poly (L-lysine) for targeted gene delivery to leukemia T cells

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Improved gene transfer to neuroblastoma cells by a monoclonal antibody targeting RET, a receptor tyrosine kinase

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer

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7 January 2021

Gene transfer into respiratory epithelial cells by targeting the polymeric immunoglobulin receptor

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https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Receptor-mediated gene delivery to human peripheral blood mononuclear cells using anti-CD3 antibody coupled to polyethylenimine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

CD5-mediated specific delivery of DNA to T lymphocytes: compartmentalization augmented by adenovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Tumor targeting with surface-shielded ligand--polycation DNA complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Biodistribution of free and N-(2-hydroxypropyl)methacrylamide copolymer-bound mesochlorin e(6) and adriamycin in nude mice bearing human ovarian carcinoma OVCAR-3 xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Polyethylenimine-mediated gene delivery: a mechanistic study

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: membrane bending model

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Effects of Polyethyleneimine on Endocytosis and Lysosome Stability

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Chloroquine and amphipathic peptide helices show synergistic transfection in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

pH-dependent bilayer destabilization by an amphipathic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Association of a pH-sensitive peptide with membrane vesicles: role of amino acid sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Pore-forming peptides induce rapid phospholipid flip-flop in membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Orientation of the pore-forming peptide GALA in POPC vesicles determined by a BODIPY-avidin/biotin binding assay

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Receptor-mediated gene transfer to cells of hepatic origin by galactosylated albumin-polylysine complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

A new gene delivery formulation of polyethylenimine/DNA complexes coated with PEG conjugated fusogenic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

High efficiency polyoma DNA transfection of chloroquine treated cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Enhanced plasmid DNA transfection with lysosomotropic agents in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Photochemical transfection: a new technology for light-induced, site-directed gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Transgenesis in mice by cytoplasmic injection of polylysine/DNA mixtures

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Size-dependent DNA mobility in cytoplasm and nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Plasmid DNA entry into postmitotic nuclei of primary rat myotubes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

The polyelectrolyte nature of F-actin and the mechanism of actin bundle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Determination of protection from serum nuclease activity by DNA-polyelectrolyte complexes using an electrophoretic method

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Poly(ethylenimine)-mediated transfection: a new paradigm for gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Kinetics and mechanism of DNA uptake into the cell nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Nuclear pores and nuclear assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Identification and characterization of nuclear pore subcomplexes in mitotic extract of human somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Nuclear envelope permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Fluorescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Getting across the nuclear pore complex

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Signal-mediated nuclear transport in proliferating and growth-arrested BALB/c 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Finding nuclear localization signals

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Nuclear targeting sequences--a consensus?

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

SV40 Large Tumor Antigen Nuclear Import Is Regulated by the Double-stranded DNA-dependent Protein Kinase Site (Serine 120) Flanking the Nuclear Localization Sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

The arginine-rich domains present in human immunodeficiency virus type 1 Tat and Rev function as direct importin beta-dependent nuclear localization signals

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Enhancement of polylysine-mediated transferrinfection by nuclear localization sequences: polylysine does not function as a nuclear localization sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Sequence requirements for plasmid nuclear import

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Cell-specific nuclear import of plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Differential expression and stability of foreign genes introduced into human fibroblasts by nuclear versus cytoplasmic microinjection

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Nuclear localization signals enhance germline transmission of a transgene in zebrafish

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Glowing zebrafish: integration, transmission, and expression of a single luciferase transgene promoted by noncovalent DNA-nuclear transport peptide complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Gene transfer into mammalian cells using histone-condensed plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Complexes of non-cationic liposomes and histone H1 mediate efficient transfection of DNA without encapsulation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Intracellular fate and nuclear targeting of plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Coupling of nuclear localization signals to plasmid DNA and specific interaction of the conjugates with importin alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Increased expression of DNA cointroduced with nuclear protein in adult rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Antisense therapy in oncology: new hope for an old idea?

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Suppression of gene expression by targeted disruption of messenger RNA: available options and current strategies.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Recent developments in the hammerhead ribozyme field

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Progress Toward the Structure and Therapeutic Use of the Hairpin Ribozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Antisense therapeutics: lessons from early clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Reversal of multidrug resistance by a liposome- MDR 1 ribozyme complex

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Bcl-2 Antisense Oligonucleotides Enhance the Cytotoxicity of Chlorambucil in B-Cell Chronic Lymphocytic Leukaemia Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Biological Effects and Cellular Uptake of c-mycAntisense Oligonucleotides and Their Cationic Liposome Complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Suppression of the malignant phenotype of melanoma cells by anti-oncogene ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Antisense Properties of End-Modified Oligonucleotides Targeted to Ha-rasOncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Polyethylenimine but not cationic lipid improves antisense activity of 3'-capped phosphodiester oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Downregulation of Akt1 inhibits anchorage-independent cell growth and induces apoptosis in cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

An antisense EGFR oligodeoxynucleotide enveloped in Lipofectin induces growth inhibition in human malignant gliomas in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Inhibition of Tumor Growth by Ribozyme-Mediated Suppression of Aberrant Epidermal Growth Factor Receptor Gene Expression

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Suppression of Fibroblast Growth Factors 1 and 2 by Antisense Oligonucleotides in Embryonic Chick Retinal Cellsin VitroInhibits Neuronal Differentiation and Survival

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Inhibition of telomerase activity of melanoma cells in vitro by antisense oligonucleotides.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Hammerhead ribozyme-mediated inhibition of telomerase activity in extracts of human hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Generation of a ribozyme-adenoviral vector against K-ras mutant human lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Ribozyme-mediated specific gene replacement of the alpha1-antitrypsin gene in human hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

A novel SV40-based vector successfully transduces and expresses an alpha 1-antitrypsin ribozyme in a human hepatoma-derived cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Adenovirus-mediated transduction of ribozymes abrogates HER-2/neu and pleiotrophin expression and inhibits tumor cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Tumor-targeted p53-gene therapy enhances the efficacy of conventional chemo/radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Activation of p53 in cervical carcinoma cells by small molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Improvement of nonviral p53 gene transfer in human carcinoma cells using glucosylated polyethylenimine derivatives.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Polyethylenimine-mediated suicide gene transfer induces a therapeutic effect for hepatocellular carcinoma in vivo by using an Epstein-Barr virus-based plasmid vector

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Intratumoral adenovirus-mediated suicide gene transfer for hepatic metastases from colorectal adenocarcinoma: results of a phase I clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Genetic prodrug activation therapy for breast cancer: A phase I clinical trial of erbB-2-directed suicide gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Prodrug activation enzymes in cancer gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Regression of established macroscopic liver metastases after in situ transduction of a suicide gene

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

In VivoGene Therapy of Cancer withE. coliPurine Nucleoside Phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Potential of Varicella zoster virus thymidine kinase as a suicide gene in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

DNA vaccination against neu reduces breast cancer incidence and metastasis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Dendritic cells in cancer immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Efficient suicide gene therapy of transduced and distant untransduced ovary tumors is correlated with significant increase of intratumoral T and NK cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Induction of a CD3+/CD56+ lymphocyte population following gene therapy with transgenic IL-2 secreting fibroblasts in a child with peripheral neuroectodermal malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA–liposome complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

Photo-Oxidative Disruption of Lysosomal Membranes Causes Apoptosis of Cultured Human Fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900046-7

7 January 2021

10.1016/S0169-409X(02)00046-7

Identifiers

DOI

1 reference

4 August 2017

1 reference