In search of authentic inhibitors of HIV-1 integration (Q34785977)

4 August 2017

title

In search of authentic inhibitors of HIV-1 integration (English)

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4 August 2017

1

Zeger Debyser

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Bénédicte Van Maele

series ordinal

3

object named as

Bénédicte Van Maele

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Erik De Clercq

object named as

Erik De Clercq

series ordinal

4

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Peter Cherepanov

series ordinal

2

object named as

Peter Cherepanov

1 reference

4 August 2017

Myriam Witvrouw

5

1 reference

4 August 2017

publication date

1 January 2002

1 reference

Antiviral Chemistry & Chemotherapy

4 August 2017

published in

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4 August 2017

volume

13

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4 August 2017

issue

1

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4 August 2017

page(s)

1-15

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publication type of scholarly work

4 August 2017

review article

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DNA-Dependent protein kinase is not required for efficient lentivirus integration

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1 reference

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Retroviral DNA integration directed by HIV integration protein in vitro

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Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

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A quantitative assay for HIV DNA integration in vivo

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Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

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Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration

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The barrier-to-autointegration protein is a host factor for HIV type 1 integration

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Mode of Interaction of G-Quartets with the Integrase of Human Immunodeficiency Virus Type 1

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Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

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The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

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The DNA-binding domain of HIV-1 integrase has an SH3-like fold

21 January 2018

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HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

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Integration of human immunodeficiency virus type 1 DNA in vitro

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Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules

21 January 2018

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HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

21 January 2018

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Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds

21 January 2018

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Backbone Cyclic Peptide, Which Mimics the Nuclear Localization Signal of Human Immunodeficiency Virus Type 1 Matrix Protein, Inhibits Nuclear Import and Virus Production in Nondividing Cells

21 January 2018

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HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

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HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

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Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

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Poly(ADP-ribose) polymerase-1 is required for efficient HIV-1 integration

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Integration complexes derived from HIV vectors for rapid assays in vitro

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Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 January 2018

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The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

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Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid system

21 January 2018

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Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

21 January 2018

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The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro

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Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

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A previously unidentified host protein protects retroviral DNA from autointegration

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Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

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Solution structure of the DNA binding domain of HIV-1 integrase

21 January 2018

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21 January 2018

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Thiazolothiazepine inhibitors of HIV-1 integrase

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HIV-1 integrase inhibitors: past, present, and future

21 January 2018

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T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1

21 January 2018

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The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

21 January 2018

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Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

21 January 2018

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Retroviral integrase inhibitors year 2000: update and perspectives

21 January 2018

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Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation

21 January 2018

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Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

21 January 2018

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Suppression of human immunodeficiency virus type 1 activity in vitro by oligonucleotides which form intramolecular tetrads

21 January 2018

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Retroviral integrases and their cousins

21 January 2018

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Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration

21 January 2018

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Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

21 January 2018

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Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication

21 January 2018

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Structural basis of DNA bridging by barrier-to-autointegration factor

21 January 2018

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Specific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integrase

21 January 2018

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Mutational analysis of the integrase protein of human immunodeficiency virus type 2

21 January 2018

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Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

21 January 2018

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4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells

21 January 2018

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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

21 January 2018

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An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase

21 January 2018

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Repair of gaps in retroviral DNA integration intermediates

21 January 2018

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Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1.

21 January 2018

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Hydrazide-containing inhibitors of HIV-1 integrase.

21 January 2018

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Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

21 January 2018

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10.1177/095632020201300101

21 January 2018

Identifiers

DOI

1 reference

4 August 2017

1 reference