XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice (Q34624530)

3 August 2017

title

XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice (English)

1 reference

3 August 2017

Catherine T Yan

1

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3 August 2017

Dhruv Kaushal

2

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3 August 2017

Michael Murphy

3

1 reference

3 August 2017

Yu Zhang

4

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3 August 2017

Abhishek Datta

5

1 reference

3 August 2017

Changzhong Chen

6

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3 August 2017

Brianna Monroe

7

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3 August 2017

Gustavo Mostoslavsky

8

1 reference

3 August 2017

Kristen Coakley

9

1 reference

3 August 2017

Yijie Gao

10

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3 August 2017

Kevin D Mills

11

1 reference

3 August 2017

Alex P Fazeli

12

1 reference

3 August 2017

Suprawee Tepsuporn

13

1 reference

3 August 2017

Giles Hall

14

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3 August 2017

Richard Mulligan

15

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3 August 2017

Edward Fox

16

1 reference

3 August 2017

Roderick Bronson

17

1 reference

3 August 2017

Umberto De Girolami

18

1 reference

3 August 2017

Charles Lee

19

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3 August 2017

Frederick W Alt

20

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3 August 2017

publication date

2 May 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

language of work or name

English

0 references

published in

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3 August 2017

volume

103

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3 August 2017

issue

19

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3 August 2017

page(s)

7378-7383

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The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Recent advances in embryonal tumours of the central nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Medulloblastoma: developmental mechanisms out of control

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

The cellular response to general and programmed DNA double strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

The role of the non-homologous end-joining pathway in lymphocyte development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Transcriptional profiling of medulloblastoma in children.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Chromosomal variation in neurons of the developing and adult mammalian nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Jumping translocations are common in solid tumor cell lines and result in recurrent fusions of whole chromosome arms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Oncogene amplification in solid tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Human neural stem cells: isolation, expansion and transplantation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Production of homozygous mutant ES cells with a single targeting construct

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601938103

Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601938103

Differentiation of classic medulloblastoma into metastatic large cell medulloblastoma with focal rhabdoid differentiation in the absence of posterior fossa recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601938103

Transposition and amplification of oncogene-related sequences in human neuroblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601938103

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601938103

A molecular fingerprint for medulloblastoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

DNA ligase IV suppresses medulloblastoma formation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464348

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16670198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activated expression of the N-myc gene in human neuroblastomas and related tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16670198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0601938103

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference