IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. (Q34572769)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17030948%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis (English)

1 reference

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20 December 2019

main subject

Helicobacter hepaticus

object named as

Helicobacter hepaticus

1 reference

3

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20 December 2019

Sophie Hue

4

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20 December 2019

Kevin Maloy

10

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20 December 2019

8

Fiona Powrie

1 reference

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20 December 2019

11

Alan Sher

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20 December 2019

author name string

Marika C Kullberg

1

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20 December 2019

Dragana Jankovic

2

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20 December 2019

Peter L Gorelick

5

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20 December 2019

Brent S McKenzie

6

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20 December 2019

Daniel J Cua

7

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20 December 2019

Allen W Cheever

9

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20 December 2019

publication date

9 October 2006

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Journal of Experimental Medicine

20 December 2019

language of work or name

English

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published in

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20 December 2019

volume

203

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20 December 2019

issue

11

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20 December 2019

page(s)

2485-2494

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Interleukin-23 drives innate and T cell-mediated intestinal inflammation

20 December 2019

cites work

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IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

7 July 2018

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IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available

7 July 2018

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

7 July 2018

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IL-12 and IL-23: master regulators of innate and adaptive immunity.

7 July 2018

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7 July 2018

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7 July 2018

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

7 July 2018

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7 July 2018

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Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells

7 July 2018

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Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

7 July 2018

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Fluorogenic PCR-based quantitative detection of a murine pathogen, Helicobacter hepaticus

7 July 2018

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7 July 2018

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

7 July 2018

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7 July 2018

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Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism

7 July 2018

1 reference

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7 July 2018

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Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

7 July 2018

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Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice

7 July 2018

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Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species

7 July 2018

1 reference

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

7 July 2018

1 reference

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

7 July 2018

1 reference

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Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

7 July 2018

1 reference

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Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

27 October 2018

1 reference

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Interferon-gamma confers resistance to experimental allergic encephalomyelitis

27 October 2018

1 reference

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Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

27 October 2018

1 reference

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Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice

27 October 2018

1 reference

12 December 2020

IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice

1 reference

12 December 2020

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

1 reference

12 December 2020

Understanding the IL-23-IL-17 immune pathway

1 reference

12 December 2020

Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

1 reference

12 December 2020

Genetic ablation of interferon-? up-regulates interleukin-1? expression and enables the elicitation of collagen-induced arthritis in a nonsusceptible mouse strain

1 reference

12 December 2020

IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

1 reference

12 December 2020

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12

1 reference

12 December 2020

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

12 December 2020

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20061082

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17030948%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17030948%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

17030948

1 reference