A unified view of the DNA-damage checkpoint (Q34560932)

3 August 2017

title

A unified view of the DNA-damage checkpoint (English)

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3 August 2017

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Justine Melo

1

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3 August 2017

David Toczyski

series ordinal

2

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3 August 2017

publication date

1 April 2002

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Current Opinion in Cell Biology

3 August 2017

language of work or name

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3 August 2017

volume

14

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3 August 2017

issue

2

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3 August 2017

page(s)

237-245

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publication type of scholarly work

3 August 2017

review article

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Cell cycle checkpoint signaling through the ATM and ATR kinases

cites work

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7 January 2021

Mammalian G1- and S-phase checkpoints in response to DNA damage

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7 January 2021

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

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7 January 2021

The DNA replication checkpoint response stabilizes stalled replication forks

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7 January 2021

Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair

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7 January 2021

A Rad3–Rad26 complex responds to DNA damage independently of other checkpoint proteins

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7 January 2021

ATR and ATRIP: Partners in Checkpoint Signaling

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7 January 2021

LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae

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7 January 2021

Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae

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7 January 2021

Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct Mechanisms

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7 January 2021

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage

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7 January 2021

Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

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7 January 2021

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

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7 January 2021

Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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7 January 2021

The Mre11 complex and ATM: collaborating to navigate S phase

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7 January 2021

The yeast Xrs2 complex functions in S phase checkpoint regulation

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7 January 2021

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

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7 January 2021

Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes

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7 January 2021

Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage

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7 January 2021

Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Human homologs of Schizosaccharomyces pombe rad1, hus1, and rad9 form a DNA damage-responsive protein complex

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7 January 2021

A novel Rad24 checkpoint protein complex closely related to replication factor C.

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7 January 2021

Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC

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7 January 2021

Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

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7 January 2021

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

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7 January 2021

The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G 1 /S checkpoint activation in response to DNA damage

1 reference

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7 January 2021

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

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7 January 2021

ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation

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7 January 2021

The DNA polymerase alpha-primase complex couples DNA replication, cell-cycle progression and DNA-damage response

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7 January 2021

Activation of the DNA replication checkpoint through RNA synthesis by primase

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7 January 2021

RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast

1 reference

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7 January 2021

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

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7 January 2021

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

1 reference

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7 January 2021

S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe

1 reference

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7 January 2021

Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts

1 reference

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7 January 2021

Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

1 reference

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7 January 2021

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

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7 January 2021

1 reference

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7 January 2021

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

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7 January 2021

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

1 reference

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7 January 2021

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

1 reference

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7 January 2021

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

1 reference

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7 January 2021

Mrc1 transduces signals of DNA replication stress to activate Rad53

1 reference

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7 January 2021

Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1

1 reference

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7 January 2021

MEC1-Dependent Phosphorylation of Rad9p in Response to DNA Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Rad53 FHA Domain Associated with Phosphorylated Rad9 in the DNA Damage Checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9–Rad9 interaction after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

Yeast checkpoint genes in DNA damage processing: implications for repair and arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900312-5

7 January 2021

10.1016/S0955-0674(02)00312-5

Identifiers

DOI

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3 August 2017

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