Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease. (Q34487495)

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15 January 2020

title

Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease (English)

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15 January 2020

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15 January 2020

author name string

Michael H Donovan

1

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15 January 2020

Umar Yazdani

2

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15 January 2020

Rebekah D Norris

3

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15 January 2020

Dora Games

4

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15 January 2020

Dwight C German

5

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15 January 2020

language of work or name

English

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publication date

1 March 2006

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The Journal of Comparative Neurology

15 January 2020

published in

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15 January 2020

volume

495

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15 January 2020

page(s)

70-83

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15 January 2020

issue

1

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Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

15 January 2020

cites work

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Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus.

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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

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Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain

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Decreased neurogenesis after cholinergic forebrain lesion in the adult rat.

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Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

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Opiates inhibit neurogenesis in the adult rat hippocampus

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Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

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Reduced corpus callosum, fornix and hippocampus in PDAPP transgenic mouse model of Alzheimer's disease.

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Learning enhances adult neurogenesis in the hippocampal formation

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Hippocampal neurogenesis in adult Old World primates

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Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

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APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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7 January 2021

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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7 January 2021

Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice

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Increased hippocampal neurogenesis in Alzheimer's disease.

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Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

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Why new neurons? Possible functions for adult hippocampal neurogenesis.

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More hippocampal neurons in adult mice living in an enriched environment

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A neuronal cell line that does not express either prion or doppel proteins

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Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

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Continuation of neurogenesis in the hippocampus of the adult macaque monkey

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Comparative analysis of different methodological approaches to the in vitro study of drug-induced apoptosis

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7 January 2021

Subpopulations of proliferating cells of the adult hippocampus respond differently to physiologic neurogenic stimuli

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7 January 2021

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

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7 January 2021

The gamma-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester reduces A beta levels in vivo in plasma and cerebrospinal fluid in young (plaque-free) and aged (plaque-bearing) Tg2576 mice

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7 January 2021

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

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7 January 2021

Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus

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7 January 2021

Tritium labelling and cytochemistry of extra DNA in Acheta

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Inflammatory Blockade Restores Adult Hippocampal Neurogenesis

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7 January 2021

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7 January 2021

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7 January 2021

Adult Stem Cell Plasticity: Fact or Artifact?

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7 January 2021

Dentate gyrus volume is reduced before onset of plaque formation in PDAPP mice: a magnetic resonance microscopy and stereologic analysis

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7 January 2021

Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model

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7 January 2021

Mitotically active cells that generate neurons and astrocytes are present in multiple regions of the adult mouse hippocampus

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7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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7 January 2021

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7 January 2021

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

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7 January 2021

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

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7 January 2021

Astrocytes give rise to new neurons in the adult mammalian hippocampus.

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7 January 2021

Selective deposition of amyloid-beta protein in the entorhinal-dentate projection of a transgenic mouse model of Alzheimer's disease.

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7 January 2021

BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone.

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7 January 2021

Presenilin 1 familial Alzheimer's disease mutation leads to defective associative learning and impaired adult neurogenesis.

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7 January 2021

Heterogenous properties of dentate granule neurons in the adult rat

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7 January 2021

Presenilin-1 is expressed in neural progenitor cells in the hippocampus of adult mice

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7 January 2021

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.

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7 January 2021

New stereological methods for counting neurons

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7 January 2021

Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: digital morphometric analyses

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7 January 2021

Repetitive cocaine administration decreases neurogenesis in adult rat hippocampus

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7 January 2021

Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective

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7 January 2021

Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

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7 January 2021

Identifiers

DOI

10.1002/CNE.20840

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16432899%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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