Pharmacology of cannabinoid CB1 and CB2 receptors. (Q34442847)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9336020%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Pharmacology of cannabinoid CB1 and CB2 receptors (English)

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6 November 2019

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1

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6 November 2019

author name string

Pertwee RG

series ordinal

1

1 reference

2 August 2017

publication date

1 January 1997

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9336020%20AND%20SRC:MED&resulttype=core&format=json

Pharmacology & Therapeutics

6 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9336020%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

74

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6 November 2019

issue

2

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6 November 2019

page(s)

129-180

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publication type of scholarly work

6 November 2019

review article

1 reference

(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability

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Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain

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Δ9-Tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication

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Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides

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Pharmacological specificity of delta 9-tetrahydrocannabinol discrimination in rats

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The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling

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7 January 2021

(-)-Delta9-tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase

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7 January 2021

Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.

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7 January 2021

The ontogeny of cannabinoid receptors in the brain of postnatal and aging rats.

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Cannabinoid Receptor-Regulated Cyclic AMP Accumulation in the Rat Striatum

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Cannabinoid receptors and modulation of cyclic AMP accumulation in the rat brain

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Cannabinoid-receptor expression in human leukocytes

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7 January 2021

Stimulation of cannabinoid receptor CB1 induces krox-24 expression in human astrocytoma cells

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7 January 2021

Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1

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7 January 2021

Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor. Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression

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7 January 2021

Construction of a 3D model of the cannabinoid CB1 receptor: determination of helix ends and helix orientation

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7 January 2021

HindIII identifies a two allele DNA polymorphism of the human cannabinoid receptor gene (CNR)

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7 January 2021

Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism

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7 January 2021

Cloning and sequencing of a cDNA encoding the mouse brain-type cannabinoid receptor protein

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7 January 2021

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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7 January 2021

Effects of anandamide on cannabinoid receptors in rat brain membranes

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7 January 2021

Cannabinoid inhibition of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2.

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7 January 2021

Cannabinoid ligand-receptor signaling in the mouse uterus

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7 January 2021

Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist

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7 January 2021

A novel probe for the cannabinoid receptor

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7 January 2021

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

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7 January 2021

Suppression of lymphocyte adenosine 3':5'-cyclic monophosphate (cAMP) by delta-9-tetrahydrocannabinol

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7 January 2021

Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions

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7 January 2021

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

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7 January 2021

Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells

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7 January 2021

Expression of a cannabinoid receptor in baculovirus-infected insect cells.

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Aminoalkylindoles: Structure-Activity Relationships of Novel Cannabinoid Mimetics

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7 January 2021

Ca(2+)-dependent release from rat brain of cannabinoid receptor binding activity

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide

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7 January 2021

Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice

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7 January 2021

Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons

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7 January 2021

Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker

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7 January 2021

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction

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7 January 2021

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat.

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7 January 2021

Pharmacological activity of the cannabinoid receptor agonist, anandamide, a brain constituent

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7 January 2021

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

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7 January 2021

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

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7 January 2021

Nucleotide sequence of a human cannabinoid receptor cDNA

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7 January 2021

Molecular cloning of a human cannabinoid receptor which is also expressed in testis

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7 January 2021

Induction of the Krox 24 transcription factor in striosomes by a cannabinoid agonist

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7 January 2021

Loss of cannabinoid receptors in the substantia nigra in Huntington's disease.

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7 January 2021

Anandamide hydroxylation by brain lipoxygenase:metabolite structures and potencies at the cannabinoid receptor

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7 January 2021

Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor

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7 January 2021

Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat brain cannabinoid receptors in Xenopus oocytes

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7 January 2021

Cannabinoid receptor localization in brain

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7 January 2021

Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum

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7 January 2021

Neuronal localization of cannabinoid receptors in the basal ganglia of the rat.

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7 January 2021

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

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7 January 2021

Characterization of ligand binding to the cannabinoid receptor of rat brain membranes using a novel method: application to anandamide

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7 January 2021

Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain

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7 January 2021

Do SH-SY5Y human neuroblastoma cells express cannabinoid receptors?

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7 January 2021

Determination of the cannabinoid receptors in mouse x rat hybridoma NG108-15 cells and rat GH4C1 cells

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7 January 2021

Molecular mechanisms of toxicant-induced immunosuppression: role of second messengers

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7 January 2021

Inhibition of neuromuscular transmission in the myenteric plexus of guinea-pig ileum by omega-conotoxins GVIA, MVIIA, MVIIC and SVIB.

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7 January 2021

Inhibition of neuroblastoma adenylate cyclase by cannabinoid and nantradol compounds

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7 January 2021

Cannabinoid inhibition of adenylate cyclase: relative activity of constituents and metabolites of marihuana

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7 January 2021

Pharmacology of cannabinoid receptors

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7 January 2021

Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor

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7 January 2021

Design, Synthesis and Pharmacology of Cannabimimetic Indoles

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7 January 2021

Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor.

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7 January 2021

Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves

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7 January 2021

Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles

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7 January 2021

Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism

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7 January 2021

Roles of sulfhydryl and disulfide groups in the binding of CP-55,940 to rat brain cannabinoid receptor

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7 January 2021

Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells

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7 January 2021

Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor.

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7 January 2021

Distribution of neuronal cannabinoid receptor in the adult rat brain: a comparative receptor binding radioautography and in situ hybridization histochemistry

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7 January 2021

Localization of cannabinoid receptor in the human developing and adult basal ganglia. Higher levels in the striatonigral neurons

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7 January 2021

Initial observations on the distribution of cannabinoid receptor binding sites in the human adult basal ganglia using autoradiography

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7 January 2021

Activation of the cannabinoid receptor by delta 9-tetrahydrocannabinol reduces gamma-aminobutyric acid uptake in the globus pallidus.

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7 January 2021

Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats

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7 January 2021

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

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7 January 2021

Pharmacological evaluation of dimethylheptyl analogs of delta 9-THC: reassessment of the putative three-point cannabinoid-receptor interaction

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7 January 2021

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

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7 January 2021

Cannabinoid receptors in developing rats: detection of mRNA and receptor binding

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7 January 2021

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

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7 January 2021

Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

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7 January 2021

Molecular characterization of a peripheral receptor for cannabinoids

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7 January 2021

Cannabinoids inhibit agonist-stimulated formation of inositol phosphates in rat hippocampal cultures

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7 January 2021

The facilitating and suppressing effects of delta 9-tetrahydrocannabinol on the rise in intrasynaptosomal Ca2+ concentration in rats

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7 January 2021

Cannabinoid receptor genes

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7 January 2021

Neurobehavioral effects of delta 9-THC and cannabinoid (CB1) receptor gene expression in mice

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7 January 2021

Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study

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7 January 2021

Identification of cannabinoid receptors in cultures of rat cerebellar granule cells.

1 reference

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7 January 2021

Differential requirements of sodium for coupling of cannabinoid receptors to adenylyl cyclase in rat brain membranes

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7 January 2021

The preimplantation mouse embryo is a target for cannabinoid ligand-receptor signaling

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7 January 2021

The central neuropharmacology of psychotropic cannabinoids

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7 January 2021

The evidence for the existence of cannabinoid receptors.

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7 January 2021

Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

A preliminary investigation of the mechanisms underlying cannabinoid tolerance in the mouse vas deferens

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7 January 2021

Inhibitory effects of certain enantiomeric cannabinoids in the mouse vas deferens and the myenteric plexus preparation of guinea-pig small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Effect of phenylmethylsulphonyl fluoride on the potency of anandamide as an inhibitor of electrically evoked contractions in two isolated tissue preparations

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

AM630, a competitive cannabinoid receptor antagonist

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Pharmacological characterization of three novel cannabinoid receptor agonists in the mouse isolated vas deferens

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Further evidence for the presence of cannabinoid CB1 receptors in guinea-pig small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Further evidence for the presence of cannabinoid CB1 receptors in mouse vas deferens

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Biochemical and pharmacological characterization of cannabinoid binding sites using [3H]SR141716A.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Modulation of free intracellular calcium and cAMP by morphine and cannabinoids, alone and in combination in mouse brain and spinal cord synaptosomes

1 reference

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7 January 2021

A role for central cannabinoid and opioid systems in peripheral delta 9-tetrahydrocannabinol-induced analgesia in mice

1 reference

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7 January 2021

Selective vulnerability in Huntington's disease: preferential loss of cannabinoid receptors in lateral globus pallidus.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Characterization and distribution of binding sites for [3H]-SR 141716A, a selective brain (CB1) cannabinoid receptor antagonist, in rodent brain

1 reference

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7 January 2021

Downregulation of rat brain cannabinoid binding sites after chronic delta 9-tetrahydrocannabinol treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Changes in rat brain cannabinoid binding sites after acute or chronic exposure to their endogenous agonist, anandamide, or to delta 9-tetrahydrocannabinol

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Tetrahydrocannabinol inhibits adenyl cyclase in human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Chronic CP-55,940 alters cannabinoid receptor mRNA in the rat brain: an in situ hybridization study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Arousal-enhancing properties of the CB1 cannabinoid receptor antagonist SR 141716A in rats as assessed by electroencephalographic spectral and sleep-waking cycle analysis

1 reference

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7 January 2021

Inhibition of adenylate cyclase by delta 9-tetrahydrocannabinol in mouse spleen cells: a potential mechanism for cannabinoid-mediated immunosuppression

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Cannabinoid receptor stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding in rat brain membranes

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

An amino-terminal variant of the central cannabinoid receptor resulting from alternative splicing

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https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Structural features of the central cannabinoid CB1 receptor involved in the binding of the specific CB1 antagonist SR 141716A.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride].

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Differences in G-protein activation by mu- and delta-opioid, and cannabinoid, receptors in rat striatum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

The gene encoding the central cannabinoid receptor is located in proximal mouse Chromosome 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Differential effects of delta-9-tetrahydrocannabinol and its 11-hydroxy metabolite on sodium current in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Delta-9-tetrahydrocannabinol depresses inward sodium current in mouse neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Multiple subtypes of voltage-gated calcium channel mediate transmitter release from parasympathetic neurons in the mouse bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Cannabinoid receptor binding and messenger RNA expression in human brain: an in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Discriminative stimulus effects of anandamide in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Pharmacological specificity of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Synthesis and cannabinoid receptor binding activity of conjugated triene anandamide, a novel eicosanoid

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Effects of N-, P- and Q-type neuronal calcium channel antagonists on mammalian peripheral neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Common cannabimimetic pharmacophoric requirements between aminoalkyl indoles and classical cannabinoids

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

The conformational properties of the highly selective cannabinoid receptor ligand CP-55,940

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

Water-soluble derivatives of 1 -tetrahydrocannabinol

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2897%2982001-3

7 January 2021

10.1016/S0163-7258(97)82001-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9336020%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference