HIV integrase, a brief overview from chemistry to therapeutics (Q34247770)

31 July 2017

title

HIV integrase, a brief overview from chemistry to therapeutics (English)

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31 July 2017

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Craigie R

1

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31 July 2017

publication date

9 May 2001

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Journal of Biological Chemistry

31 July 2017

language of work or name

English

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published in

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31 July 2017

volume

276

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31 July 2017

issue

26

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31 July 2017

page(s)

23213-23216

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publication type of scholarly work

31 July 2017

review article

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Molecular mechanisms in retrovirus DNA integration

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Repair of gaps in retroviral DNA integration intermediates

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Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

21 January 2018

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Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

21 January 2018

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Genetic organization, nucleotide sequence and regulation of expression of genes encoding phenol hydroxylase and catechol 1,2-dioxygenase in Acinetobacter calcoaceticus NCIB8250.

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Tn552, a novel transposable element from Staphylococcus aureus

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Mutational analysis of the integrase protein of human immunodeficiency virus type 2

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Cocrystal structure of an editing complex of Klenow fragment with DNA

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A general two-metal-ion mechanism for catalytic RNA

21 January 2018

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

21 January 2018

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Three new structures of the core domain of HIV-1 integrase: An active site that binds magnesium

21 January 2018

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High-resolution structure of the catalytic domain of avian sarcoma virus integrase

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The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations

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Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration

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Recombining the structures of HIV integrase, RuvC and RNase H.

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Retroviral integrases and their cousins

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Catalytic domain of human immunodeficiency virus type 1 integrase: identification of a soluble mutant by systematic replacement of hydrophobic residues

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Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

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Solution structure of the DNA binding domain of HIV-1 integrase

21 January 2018

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The DNA-binding domain of HIV-1 integrase has an SH3-like fold

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Central core domain of retroviral integrase is responsible for target site selection

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Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

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Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

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Mapping Features of HIV-1 Integrase Near Selected Sites on Viral and Target DNA Molecules in an Active Enzyme−DNA Complex by Photo-Cross-Linking

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Photo-Cross-Linking Studies Suggest a Model for the Architecture of an Active Human Immunodeficiency Virus Type 1 Integrase−DNA Complex

21 January 2018

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X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

21 January 2018

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Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

21 January 2018

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Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

21 January 2018

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Three-dimensional structure of the Tn5 synaptic complex transposition intermediate

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Tn 552 transposase catalyzes concerted strand transfer in vitro

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 January 2018

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Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

21 January 2018

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HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

21 January 2018

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Modeling the late steps in HIV-1 retroviral integrase-catalyzed DNA integration

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HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

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21 January 2018

Identifiers

DOI

10.1074/JBC.R100027200

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31 July 2017

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