The immune system in atherosclerosis (Q34164644)

31 July 2017

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title

The immune system in atherosclerosis (English)

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31 July 2017

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Göran K Hansson

1

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31 July 2017

Andreas Hermansson

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 March 2011

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31 July 2017

9

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inferred from page(s)

published in

Nature Immunology

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31 July 2017

12

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31 July 2017

204-212

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31 July 2017

3

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https://scigraph.springernature.com/pub.10.1038/ni.2001

31 July 2017

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cites work

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The macrophage scavenger receptor type A directs modified proteins to antigen presentation

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Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

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Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease

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Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia

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Phosphorylcholine-targeting immunization reduces atherosclerosis

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The LDL modification hypothesis of atherogenesis: an update

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The immune response in atherosclerosis: a double-edged sword

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Cardiovascular morbidity and mortality in rheumatoid arthritis

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Antibody titers against oxidized LDL are not elevated in patients with familial hypercholesterolemia

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IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis

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12 December 2020

Differential expression patterns of proinflammatory and antiinflammatory mediators during atherogenesis in mice

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12 December 2020

Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-/- mice

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12 December 2020

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

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12 December 2020

The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges

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12 December 2020

Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice

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12 December 2020

Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications

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12 December 2020

Proatherogenic immune responses are regulated by the PD-1/PD-L pathway in mice.

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12 December 2020

Cytokines in atherosclerosis: pathogenic and regulatory pathways

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Cardiovascular risk prediction: basic concepts, current status, and future directions

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12 December 2020

Immunization of low-density lipoprotein receptor deficient (LDL-RD) mice with heat shock protein 65 (HSP-65) promotes early atherosclerosis

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12 December 2020

Inflammation and atherosclerosis

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12 December 2020

IFN-gamma potentiates atherosclerosis in ApoE knock-out mice

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12 December 2020

Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands

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12 December 2020

Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions

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12 December 2020

Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model

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12 December 2020

Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe(-/-) mice

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12 December 2020

Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells

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12 December 2020

Identification of immune responses against aldehyde-modified peptide sequences in apoB associated with cardiovascular disease

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12 December 2020

Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques.

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12 December 2020

Attenuated atherosclerosis upon IL-17R signaling disruption in LDLr deficient mice.

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12 December 2020

Membrane prostaglandin E synthase-1: a novel therapeutic target

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12 December 2020

Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha

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12 December 2020

Immunomodulation of atherosclerosis: implications for vaccine development

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12 December 2020

Natural regulatory T cells control the development of atherosclerosis in mice

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12 December 2020

Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice.

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12 December 2020

Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress

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12 December 2020

Autoantibodies against modified low-density lipoproteins in coronary artery disease

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12 December 2020

Adoptive transfer of CD4+ T cells reactive to modified low-density lipoprotein aggravates atherosclerosis.

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12 December 2020

Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL.

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12 December 2020

Biological, clinical and population relevance of 95 loci for blood lipids

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12 December 2020

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice

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12 December 2020

The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice

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12 December 2020

TNF and congestive heart failure: therapeutic possibilities

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12 December 2020

B-lymphocyte deficiency increases atherosclerosis in LDL receptor-null mice

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12 December 2020

Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis.

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12 December 2020

Emerging role of Toll-like receptors in atherosclerosis

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12 December 2020

Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells

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12 December 2020

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

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12 December 2020

Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice

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12 December 2020

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12 December 2020

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment

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12 December 2020

Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events

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12 December 2020

The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice

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12 December 2020

Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice

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12 December 2020

Interleukin-18 enhances atherosclerosis in apolipoprotein E(-/-) mice through release of interferon-gamma

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12 December 2020

No increased occurrence of ischemic heart disease prior to the onset of rheumatoid arthritis: results from two Swedish population-based rheumatoid arthritis cohorts.

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12 December 2020

Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis

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12 December 2020

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

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12 December 2020

Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation

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12 December 2020

Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice

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12 December 2020

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines

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12 December 2020

IFN-gamma deficiency exerts gender-specific effects on atherogenesis in apolipoprotein E-/- mice

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12 December 2020

Influence of interferon-gamma on the extent and phenotype of diet-induced atherosclerosis in the LDLR-deficient mouse

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12 December 2020

Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis

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12 December 2020

Medicine. Tackling two diseases with HDL.

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12 December 2020

Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance

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12 December 2020

The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

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12 December 2020

B cell depletion reduces the development of atherosclerosis in mice

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12 December 2020

Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins

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12 December 2020

Inflammation, atherosclerosis, and coronary artery disease

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12 December 2020

European biologicals registers: methodology, selected results and perspectives

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12 December 2020

High plasma concentrations of autoantibodies against native peptide 210 of apoB-100 are related to less coronary atherosclerosis and lower risk of myocardial infarction

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12 December 2020

Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice

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12 December 2020

Atorvastatin restores Lck expression and lipid raft-associated signaling in T cells from patients with systemic lupus erythematosus.

1 reference

12 December 2020

Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells

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12 December 2020

Effect of immunization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits

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12 December 2020

Role of naturally occurring CD4+ CD25+ regulatory T cells in experimental atherosclerosis

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12 December 2020

Mouse cytomegalovirus antigenic immune stimulation is sufficient to aggravate atherosclerosis in hypercholesterolemic mice

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12 December 2020

Chemokines in atherosclerosis: an update

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12 December 2020

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

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12 December 2020

Autoimmune and inflammatory mechanisms in atherosclerosis

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12 December 2020

Involvement of the antimicrobial peptide LL-37 in human atherosclerosis

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12 December 2020

Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

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12 December 2020

Adaptive immunity and atherosclerosis

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12 December 2020

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability

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12 December 2020

Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient mice

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12 December 2020

ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis

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12 December 2020

T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses

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12 December 2020

IL-33 reduces the development of atherosclerosis

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12 December 2020

Heat shock proteins and immune system

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12 December 2020

T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein

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12 December 2020

Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E

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12 December 2020

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

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12 December 2020

Blockade of interleukin-12 function by protein vaccination attenuates atherosclerosis.

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12 December 2020

Mast cells: multipotent local effector cells in atherothrombosis

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12 December 2020

Modulation of atherosclerosis in mice by Toll-like receptor 2

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12 December 2020

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

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12 December 2020

T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia

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12 December 2020

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

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12 December 2020

CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice

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12 December 2020

Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis

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12 December 2020

Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice

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12 December 2020

Recombinant human antibodies against aldehyde-modified apolipoprotein B-100 peptide sequences inhibit atherosclerosis

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12 December 2020

Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes

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12 December 2020

Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesions

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12 December 2020

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

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12 December 2020

Effect of immune deficiency on lipoproteins and atherosclerosis in male apolipoprotein E-deficient mice

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12 December 2020

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

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12 December 2020

The unfolded protein response is an important regulator of inflammatory genes in endothelial cells

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12 December 2020

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

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12 December 2020

Innate immune signals in atherosclerosis

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12 December 2020

Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis

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12 December 2020

Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice

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12 December 2020

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

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12 December 2020

Targeted deletions of cyclooxygenase-2 and atherogenesis in mice.

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12 December 2020

Cardiovascular disease risk factors: epidemiology and risk assessment.

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12 December 2020

Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo.

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12 December 2020

Pleiotropic effects of statins

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12 December 2020

Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register

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12 December 2020

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

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12 December 2020

Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis

1 reference

12 December 2020

Mucosal administration of heat shock protein-65 decreases atherosclerosis and inflammation in aortic arch of low-density lipoprotein receptor-deficient mice

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12 December 2020

Statins in rheumatoid arthritis--two birds with one stone?

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12 December 2020

Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice

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12 December 2020

Identifiers

DOI

10.1038/NI.2001

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Dimensions Publication ID

31 July 2017

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