The relationship between the roles of BRCA genes in DNA repair and cancer predisposition (Q34163219)

31 July 2017

title

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition (English)

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31 July 2017

Andrew Tutt

1

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31 July 2017

Alan Ashworth

series ordinal

2

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31 July 2017

publication date

1 December 2002

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Trends in Molecular Medicine

31 July 2017

language of work or name

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31 July 2017

volume

8

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31 July 2017

issue

12

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31 July 2017

page(s)

571-576

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publication type of scholarly work

31 July 2017

review article

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THE GENETICS OF BREAST CANCER SUSCEPTIBILITY

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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

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hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

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BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

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Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

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Brca1 controls homology-directed DNA repair

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DNA double strand break repair in mammalian cells

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Nucleotide Excision Repair in Mammalian Cells

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BRCA1 Required for Transcription-Coupled Repair of Oxidative DNA Damage

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BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair.

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Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

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A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

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Genomic instability in mice lacking histone H2AX

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

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BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

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RAD51 Interacts with the Evolutionarily Conserved BRC Motifs in the Human Breast Cancer Susceptibility Gene brca2

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Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

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Homology-directed repair is a major double-strand break repair pathway in mammalian cells

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BRCA2 is required for homology-directed repair of chromosomal breaks

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Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

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Identifiers

DOI

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31 July 2017

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