Therapeutic targeting of human immunodeficiency virus type-1 latency: current clinical realities and future scientific possibilities (Q34133579)

31 July 2017

title

Therapeutic targeting of human immunodeficiency virus type-1 latency: current clinical realities and future scientific possibilities (English)

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31 July 2017

Butera ST

1

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31 July 2017

publication date

1 December 2000

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31 July 2017

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31 July 2017

volume

48

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31 July 2017

issue

3

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31 July 2017

page(s)

143-176

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publication type of scholarly work

31 July 2017

review article

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Additive effects of IL-2 and protein kinase A type I antagonist on function of T cells from HIV-infected patients on HAART.

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Mechanisms of HIV-1 latency

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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Inhibition of HIV-1 Replication by Combination of a Novel Inhibitor of TNF-α With AZT

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Early effects of antiretroviral combination therapy on activation, apoptosis and regeneration of T cells in HIV-1-infected children and adolescents

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Cytokines from vaccine-induced HIV-1 specific cytotoxic T lymphocytes: effects on viral replication

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Changes in blood CD8+ lymphocyte activation status and plasma HIV RNA levels during antiretroviral therapy

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Blocking of Tat-dependent HIV-1 RNA modification by an inhibitor of RNA polymerase II processivity

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HIV-1 Reactivation in Resting Peripheral Blood Mononuclear Cells of Infected Adults Upon in Vitro CD4 Cross-Linking by Ligands of the CDR2-Loop in Extracellular Domain 1

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Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection

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7 January 2021

Quiescent T Lymphocytes as an Inducible Virus Reservoir in HIV-1 Infection

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7 January 2021

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

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7 January 2021

Cytokine involvement in viral permissiveness and the progression of HIV disease

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7 January 2021

Application of Latent HIV-1 Infected Cellular Models to Therapeutic Intervention

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7 January 2021

Human immunodeficiency virus type 1 RNA expression by four chronically infected cell lines indicates multiple mechanisms of latency

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7 January 2021

Compounds that target novel cellular components involved in HIV-1 transcription

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7 January 2021

Analysis of human immunodeficiency virus in semen: indications of a genetically distinct virus reservoir

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During HIV-1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion

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Outpatient Continuous Intravenous Interleukin‐2 or Subcutaneous, Polyethylene Glycol‐Modified Interleukin‐2 in Human Immunodeficiency Virus‐Infected Patients: A Randomized, Controlled, Multicenter Study

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7 January 2021

Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection

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7 January 2021

Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo

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7 January 2021

Highly purified CD25- resting T cells cannot be infected de novo with HIV-1

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Latent reservoirs of HIV: obstacles to the eradication of virus

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In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency

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Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

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7 January 2021

Early establishment of a pool of latently infected, resting CD4 + T cells during primary HIV-1 infection

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7 January 2021

Induction of HIV-1 Replication in Latently Infected CD4+ T Cells Using a Combination of Cytokines

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7 January 2021

Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy

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7 January 2021

Re-emergence of HIV after stopping therapy

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7 January 2021

Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy

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7 January 2021

Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication

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7 January 2021

The critical role of p38 MAP kinase in T cell HIV-1 replication.

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HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

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Association between Culturable Human Immunodeficiency Virus Type 1 (HIV‐1) in Semen and HIV‐1 RNA Levels in Semen and Blood: Evidence for Compartmentalization of HIV‐1 between Semen and Blood

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7 January 2021

Inhibition of HIV activation in latently infected cells by flavonoid compounds

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7 January 2021

Casein kinase II is a selective target of HIV-1 transcriptional inhibitors

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7 January 2021

Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency

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7 January 2021

The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

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Highly active antiretroviral therapy normalizes the function of progenitor cells in human immunodeficiency virus-infected patients

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7 January 2021

HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression

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Binding of NF-kB to the HIV-1 LTR Is Not Sufficient to Induce HIV-1 LTR Activity

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7 January 2021

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7 January 2021

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A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency

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Mutations in thetatGene Are Responsible for Human Immunodeficiency Virus Type 1 Postintegration Latency in the U1 Cell Line

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7 January 2021

Highly active antiretroviral therapy results in a decrease in CD8+ T cell activation and preferential reconstitution of the peripheral CD4+ T cell population with memory rather than naive cells

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7 January 2021

Antigen-driven CD4+ T cell and HIV-1 dynamics: residual viral replication under highly active antiretroviral therapy

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7 January 2021

Viral Dynamics in HIV-1 Infection

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Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral Therapy

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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

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7 January 2021

Limited CD4+ T-cell renewal in early HIV-1 infection: Effect of highly active antiretroviral therapy

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7 January 2021

Host-cell positive transcription elongation factor b kinase activity is essential and limiting for HIV type 1 replication

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7 January 2021

Biological and biochemical characterization of a cloned Leu-3- cell surviving infection with the acquired immune deficiency syndrome retrovirus

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7 January 2021

Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line

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7 January 2021

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone

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7 January 2021

Generation of endogenous tumour necrosis factor-alpha in MOLT-4 cells during the acute replication phase of human immunodeficiency virus type 1 determines the subsequent latent infection

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7 January 2021

Acridone derivatives are selective inhibitors of HIV-1 replication in chronically infected cells

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7 January 2021

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

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7 January 2021

Dynamics of viral load rebound and immunological changes after stopping effective antiretroviral therapy

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7 January 2021

Molecular Basis of Latency in Pathogenic Human Viruses

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Cellular Transcription Factors Involved in the Regulation of HIV-1 Gene Expression

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7 January 2021

Chimeric toxins targeted to the human immunodeficiency virus type 1 envelope glycoprotein augment the in vivo activity of combination antiretroviral therapy in thy/liv-SCID-Hu mice

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7 January 2021

The in vitro induction of human immunodeficiency virus (HIV) replication in purified protein derivative-positive HIV-infected persons by recall antigen response to Mycobacterium tuberculosis is the result of a balance of the effects of endogenous in

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7 January 2021

Therapeutic vaccines in HIV.1 infection

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7 January 2021

Interleukin 1 induces HIV-1 expression in chronically infected U1 cells: blockade by interleukin 1 receptor antagonist and tumor necrosis factor binding protein type 1.

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7 January 2021

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

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7 January 2021

Multiple modes of cellular activation and virus transmission in HIV infection: A role for chronically and latently infected cells in sustaining viral replication

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7 January 2021

Ongoing HIV dissemination during HAART.

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7 January 2021

A proliferative p53-responsive element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeat

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7 January 2021

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

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7 January 2021

3-year suppression of HIV viremia with indinavir, zidovudine, and lamivudine

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7 January 2021

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

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7 January 2021

An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication

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7 January 2021

Rate of HIV-1 RNA rebound upon stopping antiretroviral therapy

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7 January 2021

Heat shock induces HIV-1 replication in chronically infected promyelocyte cell line OM10.1.

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7 January 2021

Follicular dendritic cells and human immunodeficiency virus infectivity

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7 January 2021

CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells.

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7 January 2021

Lymphocyte kinetics and precursor frequency-dependent recovery of CD4(+)CD45RA(+)CD62L(+) naive T cells following triple-drug therapy for HIV type 1 infection

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7 January 2021

HIV-1 RNA levels in cerebrospinal fluid and plasma correlate with AIDS dementia

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7 January 2021

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

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7 January 2021

Inhibition of HIV type 1 replication in chronically infected monocytes and lymphocytes by retrovirus-mediated gene transfer of anti-Rev single-chain variable fragments

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7 January 2021

Inhibition of HIV Replication in Acute and Chronic Infections in Vitro by a Tat Antagonist

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7 January 2021

Germinal centre CD4+ T cells are an important site of HIV replication in vivo.

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7 January 2021

Recombinant human IL-16 inhibits HIV-1 replication and protects against activation-induced cell death (AICD)

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7 January 2021

AIDS pathogenesis: the role of accessory gene mutations, leading to formation of long-lived persistently infected cells and/or apoptosis-inducing HIV-1 particles.

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Doxorubicin inhibits Tat-dependent transactivation of HIV type 1 LTR.

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7 January 2021

Taking a new TAK on Tat transactivation

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7 January 2021

Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy

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7 January 2021

Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection

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7 January 2021

Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4+ T cells in vitro and in vivo

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7 January 2021

Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells

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7 January 2021

Naturally occurring accessory gene mutations lead to persistent human immunodeficiency virus type 1 infection of CD4-positive T cells

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7 January 2021

HIV replication in CD4+ T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous beta-chemokines and the viral inductive effects of other endogenous cytokines

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7 January 2021

Interleukin 2 induces CD8+ T cell-mediated suppression of human immunodeficiency virus replication in CD4+ T cells and this effect overrides its ability to stimulate virus expression

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7 January 2021

Inhibition of NF-kappa B by sodium salicylate and aspirin

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7 January 2021

Nonproductive human immunodeficiency virus type 1 infection in nucleoside-treated G0 lymphocytes

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Type I interferon is a powerful inhibitor of in vivo HIV-1 infection and preserves human CD4(+) T cells from virus-induced depletion in SCID mice transplanted with human cells

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7 January 2021

Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells

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7 January 2021

Immunologic Responses Associated with 12 Weeks of Combination Antiretroviral Therapy Consisting of Zidovudine, Lamivudine, and Ritonavir: Results of AIDS Clinical Trials Group Protocol 315

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7 January 2021

T cell-derived suppressive activity: evidence of autocrine noncytolytic control of HIV type 1 transcription and replication

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7 January 2021

Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation

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7 January 2021

Serum Vpr regulates productive infection and latency of human immunodeficiency virus type 1

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

An anti-CD45RO immunotoxin eliminates T cells latently infected with HIV-1 in vitro

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Inhibition of HIV-1 replication and NF-x B activity by cysteine and cysteine derivatives

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

The non-immunosuppressive cyclosporin A analogue SDZ NIM 811 inhibits cyclophilin A incorporation into virions and virus replication in human immunodeficiency virus type 1-infected primary and growth-arrested T cells

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7 January 2021

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7 January 2021

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7 January 2021

Factors Secreted by Human T Lymphotropic Virus Type I (HTLV-I)–infected Cells Can Enhance or Inhibit Replication of HIV-1 in HTLV-I–uninfected Cells: Implications for In Vivo Coinfection with HTLV-I and HIV-1

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7 January 2021

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7 January 2021

9-Nitrocamptothecin Inhibits Tumor Necrosis Factor-Mediated Activation of Human Immunodeficiency Virus Type 1 and Enhances Apoptosis in a Latently Infected T Cell Clone

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7 January 2021

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7 January 2021

Inhibition of replication of reactivated human immunodeficiency virus type 1 (HIV-1) in latently infected U1 cells transduced with an HIV-1 long terminal repeat-driven PKR cDNA construct

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7 January 2021

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7 January 2021

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7 January 2021

Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT

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7 January 2021

HIV-1 rebound during interruption of highly active antiretroviral therapy has no deleterious effect on reinitiated treatment. Comet Study Group

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7 January 2021

In vitro separation and expansion of CD4 lymphocytes from HIV-infected individuals without activation of HIV infection

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7 January 2021

Effect of Granulocyte Colony‐Stimulating Factor (G‐CSF) in Human Immunodeficiency Virus‐Infected Patients: Increase in Numbers of Naive CD4 Cells and CD34 Cells Makes G‐CSF a Candidate for Use in Gene Therapy or to Support Antiretroviral Therapy

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7 January 2021

Potent Inhibition of HIV Type 1 Replication by an Antiinflammatory Alkaloid, Cepharanthine, in Chronically Infected Monocytic Cells

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7 January 2021

Inhibition of human immunodeficiency virus type 1 replication by combination of transcription inhibitor K-12 and other antiretroviral agents in acutely and chronically infected cells

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7 January 2021

Macrophages as a source of HIV during opportunistic infections

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7 January 2021

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

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7 January 2021

Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group

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7 January 2021

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

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7 January 2021

Low-dose IL-2 reduces lymphocyte apoptosis and increases naive CD4 cells in HIV-1 patients treated with HAART

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7 January 2021

How immune-based interventions can change HIV therapy

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7 January 2021

Lymphoid organs function as major reservoirs for human immunodeficiency virus

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7 January 2021

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

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7 January 2021

Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: Implications for antiviral therapy

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7 January 2021

NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro

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7 January 2021

Decay characteristics of HIV-1-infected compartments during combination therapy

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7 January 2021

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.

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7 January 2021

Virus Burden in Lymph Nodes and Blood of Subjects with Primary Human Immunodeficiency Virus Type 1 Infection on Bitherapy

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7 January 2021

High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR

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7 January 2021

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

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7 January 2021

Lack of T-cell proliferative response to HIV-1 antigens after 1 year of highly active antiretroviral treatment in early HIV-1 disease

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7 January 2021

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression

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7 January 2021

Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms

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7 January 2021

Transforming growth factor beta suppresses human immunodeficiency virus expression and replication in infected cells of the monocyte/macrophage lineage

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7 January 2021

Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist

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7 January 2021

Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency

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7 January 2021

Lipopolysaccharide is a potent monocyte/macrophage-specific stimulator of human immunodeficiency virus type 1 expression

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7 January 2021

Immuno-activation with anti-CD3 and recombinant human IL-2 in HIV-1-infected patients on potent antiretroviral therapy

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7 January 2021

Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro

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7 January 2021

Interleukin-10 enhances tumor necrosis factor-alpha activation of HIV-1 transcription in latently infected T cells

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7 January 2021

Inhibition of HIV-1 replication by retroviral vectors expressing monomeric and multimeric hammerhead ribozymes

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7 January 2021

The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy

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7 January 2021

Activated B lymphocytes from human immunodeficiency virus-infected individuals induce virus expression in infected T cells and a promonocytic cell line, U1

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7 January 2021

Naı̈ve and Memory CD4 T Cells Differ in Their Susceptibilities to Human Immunodeficiency Virus Type 1 Infection following CD28 Costimulation: Implications for Transmission and Pathogenesis

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7 January 2021

N-Acetylcysteine Inhibits Latent HIV Expression in Chronically Infected Cells

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7 January 2021

HIV does not replicate in naive CD4 T cells stimulated with CD3/CD28

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7 January 2021

Vigorous HIV-1-Specific CD4 + T Cell Responses Associated with Control of Viremia

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7 January 2021

Correlates of latent and productive HIV type-1 infection in tonsillar CD4 + T cells

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7 January 2021

CD8+ T cells from HIV type 1-seronegative individuals suppress virus replication in acutely infected cells

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7 January 2021

Inhibition of HIV-1 replication by a Tat transdominant negative mutant in human peripheral blood lymphocytes from healthy donors and HIV-1-infected patients

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7 January 2021

Induction of monocytic differentiation and NF-kappa B-like activities by human immunodeficiency virus 1 infection of myelomonoblastic cells

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7 January 2021

Megalomicin inhibits HIV-1 replication and interferes with gp160 processing

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7 January 2021

Inhibition of Human Immunodeficiency Virus Type 1 Replication by a Bioavailable Serine/Threonine Kinase Inhibitor, Fasudil Hydrochloride

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7 January 2021

Construction of a Novel Virus That Targets HIV-1-Infected Cells and Controls HIV-1 Infection

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7 January 2021

The reservoir for HIV-1 in human peripheral blood is a T cell that maintains expression of CD4

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7 January 2021

Cellular and Anatomical Reservoirs of HIV-1 in Patients Receiving Potent Antiretroviral Combination Therapy

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7 January 2021

HIV load in highly purified CD8+ T cells retrieved from pulmonary and blood compartments

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7 January 2021

Blocked early-stage latency in the peripheral blood cells of certain individuals infected with human immunodeficiency virus type 1

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7 January 2021

Role of p38 mitogen-activated protein kinase in HIV type 1 production in vitro

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7 January 2021

Interleukin 18 stimulates HIV type 1 in monocytic cells

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7 January 2021

Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy

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7 January 2021

Engagement of adhesion molecules (CD18, CD11a, CD45, CD44, and CD58) enhances human immunodeficiency virus type 1 replication in monocytic cells through a tumor necrosis factor-modulated pathway

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7 January 2021

Rates of shutdown of HIV-1 into latency: roles of the LTR and tat/rev/vpu gene region

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7 January 2021

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

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7 January 2021

Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro

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7 January 2021

Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro

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7 January 2021

Activation of virus replication after vaccination of HIV-1-infected individuals.

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7 January 2021

Asymptomatic HIV infection is characterized by rapid turnover of HIV RNA in plasma and lymph nodes but not of latently infected lymph-node CD4+ T cells

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7 January 2021

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

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7 January 2021

Expression of the c-myc proto-oncogene is essential for HIV-1 infection in activated T cells.

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7 January 2021

Highly purified quiescent human peripheral blood CD4+ T cells are infectible by human immunodeficiency virus but do not release virus after activation

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7 January 2021

The Unenlarged Lymph Nodes of HIV-1–infected, Asymptomatic Patients with High CD4 T Cell Counts Are Sites for Virus Replication and CD4 T Cell Proliferation. The Impact of Highly Active Antiretroviral Therapy

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7 January 2021

Cyclosporins: immunosuppressive drugs with anti-HIV-1 activity

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7 January 2021

Activation of Latent HIV-1 by Mycobacterium tuberculosis and Its Purified Protein Derivative in Alveolar Macrophages From HIV-Infected Individuals in Vitro

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7 January 2021

Persistent productive HIV infection in EBV-transformed B lymphocytes

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7 January 2021

Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells

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7 January 2021

Interleukin-16 inhibits human immunodeficiency virus type 1 entry and replication in macrophages and in dendritic cells

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7 January 2021

Inhibition of Acute-, Latent-, and Chronic-Phase Human Immunodeficiency Virus Type 1 (HIV-1) Replication by a Bistriazoloacridone Analog That Selectively Inhibits HIV-1 Transcription

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7 January 2021

Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes

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7 January 2021

Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.

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7 January 2021

IL-16 anti-HIV-1 therapy

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7 January 2021

Hexamethylene bisacetamide activates the human immunodeficiency virus type 1 provirus by an NF-kappa B-independent mechanism

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7 January 2021

Tumour necrosis factors (α, β) induced by HIV-1 in peripheral blood mononuclear cells potentiate virus replication

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7 January 2021

Immune stimulation and HIV-1 viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Inhibition of human immunodeficiency virus replication in acutely infected CD4+ cells by CD8+ cells involves a noncytotoxic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

CD7 expression distinguishes subsets of CD4(+) T cells with distinct functional properties and ability to support replication of HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Viral dynamics in human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Interleukin 10 blocks HIV replication in macrophages by inhibiting the autocrine loop of tumor necrosis factor alpha and interleukin 6 induction of virus

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Cytokine regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

CD8+ anti-human immunodeficiency virus suppressor activity (CASA) in response to antiretroviral therapy: loss of CASA is associated with loss of viremia.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

HIV-1 latency due to the site of proviral integration

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Broad-spectrum antiviral activity and mechanism of antiviral action of the fluoroquinolone derivative K-12.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Productive infection of neonatal CD8+ T lymphocytes by HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Potent antiretroviral therapy of primary human immunodeficiency virus type 1 (HIV-1) infection: partial normalization of T lymphocyte subsets and limited reduction of HIV-1 DNA despite clearance of plasma viremia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Topotecan inhibits human immunodeficiency virus type 1 infection through a topoisomerase-independent mechanism in a cell line with altered topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Human CD4+ cells transfected with IL-16 cDNA are resistant to HIV-1 infection: inhibition of mRNA expression

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

Transcription elongation factor P-TEFb is required for HIV-1 Tat transactivation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2800%2900133-9

7 January 2021

10.1016/S0166-3542(00)00133-9

Identifiers

DOI

1 reference

31 July 2017

1 reference