Genetic and biochemical characterization of a novel umuD mutation: insights into a mechanism for UmuD self-cleavage (Q33995258)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11114935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Genetic and biochemical characterization of a novel umuD mutation: insights into a mechanism for UmuD self-cleavage (English)

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2 November 2019

3

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2 November 2019

author name string

M D Sutton

series ordinal

1

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2 November 2019

M Kim

series ordinal

2

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2 November 2019

publication date

1 January 2001

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2 November 2019

language of work or name

English

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published in

Journal of Bacteriology

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2 November 2019

volume

183

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2 November 2019

issue

1

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2 November 2019

page(s)

347-357

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Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis

2 November 2019

cites work

1 reference

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Identification of additional genes belonging to the LexA regulon in Escherichia coli

28 July 2018

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Visualization of two binding sites for the Escherichia coli UmuD'(2)C complex (DNA pol V) on RecA-ssDNA filaments

28 July 2018

1 reference

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A role for the umuDC gene products of Escherichia coli in increasing resistance to DNA damage in stationary phase by inhibiting the transition to exponential growth

28 July 2018

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Common protein architecture and binding sites in proteases utilizing a Ser/Lys dyad mechanism

28 July 2018

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The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication

28 July 2018

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The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase

28 July 2018

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Bridging the gap: a family of novel DNA polymerases that replicate faulty DNA.

28 July 2018

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Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

28 July 2018

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A plethora of lesion-replicating DNA polymerases

28 July 2018

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Novel DNA polymerases offer clues to the molecular basis of mutagenesis

28 July 2018

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A model for a umuDC-dependent prokaryotic DNA damage checkpoint

28 July 2018

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UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

28 July 2018

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Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.

28 July 2018

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Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor

28 July 2018

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Linkage map of Escherichia coli K-12, edition 10: the traditional map

28 July 2018

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Skiing the black diamond slope: Progress on the biochemistry of translesion DNA synthesis

28 July 2018

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Novel Escherichia coli umuD ′ Mutants: Structure-Function Insights into SOS Mutagenesis

28 July 2018

1 reference

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Specific RecA amino acid changes affect RecA–UmuD′C interaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Intermolecular cleavage by UmuD-like mutagenesis proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Genetic requirements and mutational specificity of the Escherichia coli SOS mutator activity

28 July 2018

1 reference

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Quantitation of the inhibition of hfr x F− recombination by the mutagenesis complex UmuD′C

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

The UmuD' protein filament and its potential role in damage induced mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Interactions of Escherichia coli UmuD with activated RecA analyzed by cross-linking UmuD monocysteine derivatives

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

The genetic requirements for UmuDC-mediated cold sensitivity are distinct from those for SOS mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Purification of a soluble UmuD'C complex from Escherichia coli. Cooperative binding of UmuD'C to single-stranded DNA.

28 July 2018

1 reference

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Specific in vivo protein-protein interactions between Escherichia coli SOS mutagenesis proteins

28 July 2018

1 reference

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Structure of the UmuD' protein and its regulation in response to DNA damage

28 July 2018

1 reference

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Targeting of the UmuD, UmuD', and MucA' mutagenesis proteins to DNA by RecA protein

28 July 2018

1 reference

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LexA cleavage and other self-processing reactions

28 July 2018

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A monocysteine approach for probing the structure and interactions of the UmuD protein

28 July 2018

1 reference

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Biochemistry of homologous recombination in Escherichia coli

28 July 2018

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Characterization of the umu-complementing operon from R391.

28 July 2018

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DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli

28 July 2018

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Cleavage of the Escherichia coli lexA protein by the recA protease

28 July 2018

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Novel mechanism of cell division inhibition associated with the SOS response in Escherichia coli.

28 July 2018

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Prophage ψ80 is induced in Escherichia coli K12 recA430

28 July 2018

1 reference

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Identification of the amino acid substitutions in two mutant forms of the recA protein from Escherichia coli: recA441 and recA629

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Inducible DNA repair systems

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Evidence that the recA441 (tif-1) mutant of Escherichia coli K-12 contains a thermosensitive intragenic suppressor of RecA constitutive protease activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

General recombination: functions and structure of RecA protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

RecA-mediated cleavage activates UmuD for mutagenesis: mechanistic relationship between transcriptional derepression and posttranslational activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

UmuD mutagenesis protein of Escherichia coli: overproduction, purification, and cleavage by RecA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

RecA protein-dependent cleavage of UmuD protein and SOS mutagenesis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Affinity chromatography of RecA protein and RecA nucleoprotein complexes on RecA protein-agarose columns

28 July 2018

1 reference

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umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology

28 July 2018

1 reference

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Cold sensitivity induced by overproduction of UmuDC in Escherichia coli

28 July 2018

1 reference

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New recA mutations that dissociate the various RecA protein activities in Escherichia coli provide evidence for an additional role for RecA protein in UV mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'.

28 July 2018

1 reference

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Dominant negative umuD mutations decreasing RecA-mediated cleavage suggest roles for intact UmuD in modulation of SOS mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Nature of the SOS-inducing signal in Escherichia coli. The involvement of DNA replication

28 July 2018

1 reference

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Mechanism of specific LexA cleavage: autodigestion and the role of RecA coprotease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Activity of the Hsp70 chaperone complex--DnaK, DnaJ, and GrpE--in initiating phage lambda DNA replication by sequestering and releasing lambda P protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Uvm mutants of Escherichia coli K12 deficient in UV mutagenesis. I. Isolation of uvm mutants and their phenotypical characterization in DNA repair and mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Isolation and characterization of mutants of Escherichia coli deficient in induction of mutations by ultraviolet light

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Modulation of RecA nucleoprotein function by the mutagenic UmuD'C protein complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Regulation of UmuD cleavage: role of the amino-terminal tail

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

In vitro inhibition of RecA-mediated homologous pairing by UmuD'C proteins.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

The appearance of the UmuD'C protein complex in Escherichia coli switches repair from homologous recombination to SOS mutagenesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=94884

Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coli

29 October 2018

1 reference

12 December 2020

Functional domains of Escherichia coli recA protein deduced from the mutational sites in the gene

1 reference

12 December 2020

P-azidoiodoacetanilide, a new short photocrosslinker that has greater cysteine specificity than p-azidophenacyl bromide and p-azidobromoacetanilide

1 reference

12 December 2020

Interaction of Escherichia coli RecA protein with LexA repressor. I. LexA repressor cleavage is competitive with binding of a secondary DNA molecule

1 reference

12 December 2020

Mutational analysis of the RecA protein L1 region identifies this area as a probable part of the co‐protease substrate binding site

1 reference

12 December 2020

Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis

1 reference

12 December 2020

Differential cleavage of LexA and UmuD mediated by recA Pro67 mutants: implications for common LexA and UmuD binding sites on RecA

1 reference

12 December 2020

10.1128/JB.183.1.347-357.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11114935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11114935%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

11114935

1 reference