Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha (Q33841858)

29 July 2017

title

Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha (English)

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29 July 2017

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5

Myriam Gorospe

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29 July 2017

Ashish Lal

1

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29 July 2017

Tomoko Kawai

series ordinal

2

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29 July 2017

Xiaoling Yang

series ordinal

3

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29 July 2017

Krystyna Mazan-Mamczarz

series ordinal

4

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29 July 2017

publication date

28 April 2005

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29 July 2017

language of work or name

0 references

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29 July 2017

volume

24

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29 July 2017

issue

10

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29 July 2017

page(s)

1852-1862

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Prothymosin alpha associates with the oncoprotein SET and is involved in chromatin decondensation

29 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Global analysis of stress-regulated mRNA turnover by using cDNA arrays

5 July 2018

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AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis

5 July 2018

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5 July 2018

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Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells

5 July 2018

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5 July 2018

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

5 July 2018

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5 July 2018

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Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence

5 July 2018

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5 July 2018

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5 July 2018

HuR and mRNA stability

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Fifteen years of prothymosin alpha: contradictory past and new horizons

5 July 2018

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Prothymosin alpha functions as a cellular oncoprotein by inducing transformation of rodent fibroblasts in vitro

5 July 2018

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A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

5 July 2018

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5 July 2018

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HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation

5 July 2018

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5 July 2018

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Tumour prothymosin alpha content, a potential prognostic marker for primary breast cancer

5 July 2018

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5 July 2018

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HuR regulates p21 mRNA stabilization by UV light

5 July 2018

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Functional discontinuities in prothymosin alpha caused by caspase cleavage in apoptotic cells

5 July 2018

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Caspase-9 and APAF-1 form an active holoenzyme

5 July 2018

1 reference

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Regulation of translation initiation following stress.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Overexpression of prothymosin α accelerates proliferation and retards differentiation in HL-60 cells

5 July 2018

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Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

5 July 2018

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Overexpression of hepatic prothymosin alpha, a novel marker for human hepatocellular carcinoma

5 July 2018

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Gains, losses, and amplifications of DNA sequences evaluated by comparative genomic hybridization in chondrosarcomas

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Localization of the human HuR gene to chromosome 19p13.2

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes

5 July 2018

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Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Thymosins: both nuclear and cytoplasmic proteins

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

The MYC protein activates transcription of the alpha-prothymosin gene.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Prothymosin alpha antisense oligomers inhibit myeloma cell division

5 July 2018

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Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal

5 July 2018

1 reference

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Hyaluronic acid or TNF-alpha plus fibronectin triggers granulocyte macrophage-colony-stimulating factor mRNA stabilization in eosinophils yet engages differential intracellular pathways and mRNA binding proteins

5 July 2018

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Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1alpha and EGF mRNA.

21 January 2018

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Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.

29 October 2018

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29 October 2018

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Apoptosis. Life and death decisions

29 October 2018

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Comparative genomic hybridization analysis of primary cutaneous B-cell lymphomas: identification of common genomic alterations in disease pathogenesis

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142594

Differentiation-Linked Expression of Prothymosin α Gene in Human Myeloid Leukemic Cells

29 October 2018

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Detection of the anti-Hu antibody in the serum of patients with small cell lung cancer?A quantitative western blot analysis

29 October 2018

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Prothymosin alpha gene expression correlates with proliferation, not differentiation, of HL-60 cells

29 October 2018

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12 December 2020

Mutational analysis of human prothymosin alpha reveals a bipartite nuclear localization signal

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12 December 2020

Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR

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12 December 2020

Prothymosin alpha is a nuclear protein

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12 December 2020

Sensing prothymosin alpha origin, mutations and conformation with monoclonal antibodies

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600661

1 reference

29 July 2017

1 reference

29 July 2017

1 reference