APC: the plot thickens (Q33745117)

29 July 2017

title

APC: the plot thickens (English)

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29 July 2017

Bienz M

1

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29 July 2017

publication date

1 October 1999

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Current Opinion in Genetics & Development

29 July 2017

published in

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29 July 2017

volume

9

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29 July 2017

issue

5

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29 July 2017

page(s)

595-603

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publication type of scholarly work

29 July 2017

review article

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The genetic basis of patterned baldness in Drosophila

cites work

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7 January 2021

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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7 January 2021

The oncogenic activation of beta-catenin

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7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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7 January 2021

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Three-dimensional structure of the armadillo repeat region of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Axin, an inhibitor of the Wnt signalling pathway, interacts with β‐catenin, GSK‐3β and APC and reduces the β‐catenin level

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

A new Drosophila APC homologue associated with adhesive zones of epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Axin, a Negative Regulator of the Wnt Signaling Pathway, Directly Interacts with Adenomatous Polyposis Coli and Regulates the Stabilization of β-Catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

beta-catenin can be transported into the nucleus in a Ran-unassisted manner

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Nucleocytoplasmic transport

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

β-catenin is a target for the ubiquitin–proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

beta-TrCP is a negative regulator of Wnt/beta-catenin signaling pathway and dorsal axis formation in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Components of wingless signalling in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Axil, a Member of the Axin Family, Interacts with Both Glycogen Synthase Kinase 3β and β-Catenin and Inhibits Axis Formation ofXenopus Embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Bridging of β-catenin and glycogen synthase kinase-3β by Axin and inhibition of β-catenin-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Axin prevents Wnt-3a-induced accumulation of beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta -catenin and promotes GSK-3beta -dependent phosphorylation of beta -catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Functional domains of axin. Importance of the C terminus as an oligomerization domain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Ubiquitous expression of a Drosophila adenomatous polyposis coli homolog and its localization in cortical actin caps

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Epithelial differentiation in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2900016-7

7 January 2021

10.1016/S0959-437X(99)00016-7

Identifiers

DOI

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29 July 2017

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