Structural basis of G protein-coupled receptor function (Q33690383)

28 July 2017

title

Structural basis of G protein-coupled receptor function (English)

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G protein-coupled recepteishon

28 July 2017

main subject

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author name string

Schöneberg T

series ordinal

1

1 reference

28 July 2017

Schultz G

series ordinal

2

1 reference

28 July 2017

Gudermann T

series ordinal

3

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28 July 2017

publication date

1 May 1999

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Molecular and Cellular Endocrinology

28 July 2017

published in

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28 July 2017

volume

151

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28 July 2017

issue

1-2

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28 July 2017

page(s)

181-193

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publication type of scholarly work

28 July 2017

review article

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Evidence for the direct involvement of transmembrane region 6 of the lutropin/choriogonadotropin receptor in activating Gs.

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7 January 2021

Modulation of GDP release from transducin by the conserved Glu134-Arg135 sequence in rhodopsin

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7 January 2021

C-terminal truncation of the neurokinin-2 receptor causes enhanced and sustained agonist-induced signaling. Role of receptor phosphorylation in signal attenuation

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7 January 2021

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

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7 January 2021

Oligomeric structure of muscarinic receptors is shown by photoaffinity labeling: subunit assembly may explain high- and low-affinity agonist states

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7 January 2021

Dimerization of the Extracellular Calcium-sensing Receptor (CaR) on the Cell Surface of CaR-transfected HEK293 Cells

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7 January 2021

The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin.

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7 January 2021

The probable arrangement of the helices in G protein-coupled receptors.

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7 January 2021

Structure and function of receptors coupled to G proteins

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7 January 2021

Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin

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7 January 2021

Mechanism of Transdominant Inhibition of CCR5-mediated HIV-1 Infection by ccr5Δ32

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7 January 2021

In vivo expression of the lacY gene in two segments leads to functional lac permease

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7 January 2021

A conserved tyrosine residue (Y601) in transmembrane domain 5 of the human thyrotropin receptor serves as a molecular switch to determine G-protein coupling.

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7 January 2021

Mapping of single amino acid residues required for selective activation of Gq/11 by the m3 muscarinic acetylcholine receptor

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7 January 2021

Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum

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7 January 2021

Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors

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7 January 2021

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration

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7 January 2021

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

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7 January 2021

Radiation inactivation (target size analysis) of the gonadotropin-releasing hormone receptor: evidence for a high molecular weight complex

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7 January 2021

Domain assembly of the GLUT1 glucose transporter

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7 January 2021

Dimerization of the delta opioid receptor: implication for a role in receptor internalization

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7 January 2021

Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A.

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7 January 2021

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

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7 January 2021

Molecular Basis of V2 Vasopressin Receptor/GsCoupling Selectivity

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7 January 2021

Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

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7 January 2021

1 reference

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7 January 2021

A receptor subtype involved in neuropeptide-Y-induced food intake

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7 January 2021

Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes

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7 January 2021

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

The luteinizing hormone/chorionic gonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Diversity and selectivity of receptor-G protein interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Functional and structural complexity of signal transduction via G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Molecular chaperones in cellular protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Predicting the orientation of eukaryotic membrane-spanning proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Structure and function of proteins in G-protein-coupled signal transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C.

1 reference

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7 January 2021

Truncation of the C-terminal Tail of the Follitropin Receptor Does Not Impair the Agonist- or Phorbol Ester-induced Receptor Phosphorylation and Uncoupling

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Truncation of the carboxyl-terminal region of the rat parathyroid hormone (PTH)/PTH-related peptide receptor enhances PTH stimulation of adenylyl cyclase but not phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Protease-activated receptor 3 is a second thrombin receptor in humans

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7 January 2021

Thermodynamics and kinetics of protein incorporation into membranes

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7 January 2021

Cloning and tissue distribution of the human P2Y1 receptor

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7 January 2021

Temperature sensitivity of some mutants of the lutropin/choriogonadotropin receptor

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7 January 2021

d-Arg1,d-Phe5,d-Trp7,9,Leu11Substance P Acts as a Biased Agonist toward Neuropeptide and Chemokine Receptors

1 reference

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7 January 2021

Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

The function of a highly-conserved arginine residue in activation of the muscarinic M1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

NMR and circular dichroism studies of synthetic peptides derived from the third intracellular loop of the beta-adrenoceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Conformation of a beta-adrenoceptor-derived signal transducing peptide as inferred by circular dichroism and 1H NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Bacteriorhodopsin can be refolded from two independently stable transmembrane helixes and the complementary five-helix fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A Novel Go-mediated Phototransduction Cascade in Scallop Visual Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Genetic Analysis of Receptor-Gαq Coupling Selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Functional Characterization of a Series of Mutant G Protein αq Subunits Displaying Promiscuous Receptor Coupling Properties

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Iron(III) hydroxamate transport of Escherichia coli: restoration of iron supply by coexpression of the N- and C-terminal halves of the cytoplasmic membrane protein FhuB cloned on separate plasmids

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

The role of Asp578 in maintaining the inactive conformation of the human lutropin/choriogonadotropin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Receptors for VIP, PACAP, secretin, GRF, glucagon, GLP-1, and other members of their new family of G protein-linked receptors: structure-function relationship with special reference to the human VIP-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Identification of receptor-activated G proteins: selective immunoprecipitation of photolabeled G-protein alpha subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Sequence specificity in the dimerization of transmembrane alpha-helices

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A dimerization motif for transmembrane α–helices

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A model of the lutropin/choriogonadotropin receptor: insights into the structural and functional effects of constitutively activating mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Mutational Analysis of the Relative Orientation of Transmembrane Helices I and VII in G Protein-coupled Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Different single receptor domains determine the distinct G protein coupling profiles of members of the vasopressin receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

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https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Rhodopsin-family receptors associate with small G proteins to activate phospholipase D.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Arrangement of transmembrane domains in adrenergic receptors. Similarity to bacteriorhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

1 reference

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7 January 2021

Dopamine D2 receptor dimers and receptor-blocking peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Resistance of the Dopamine D2LReceptor to Desensitization Accompanies the Up-Regulation of Receptors on to the Surface of Sf9 Cells1

1 reference

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7 January 2021

Expression of Dopamine D3 Receptor Dimers and Tetramers in Brain and in Transfected Cells

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7 January 2021

Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Identification of a Gs activator region of the β2-adrenergic receptor that is autoregulated via protein kinase A-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Mapping of beta-adrenoceptor coupling domains to Gs-protein by site-specific synthetic peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Membrane protein folding and oligomerization: the two-stage model

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Constitutively active mutants of rhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Targeting of G Protein-coupled Receptors to the Basolateral Surface of Polarized Renal Epithelial Cells Involves Multiple, Non-contiguous Structural Signals

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A Cluster of Four Novel Human G Protein-Coupled Receptor Genes Occurring in Close Proximity to CD22 Gene on Chromosome 19q13.1

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Projection structure of rhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Enhanced cleavage of an atypical intron of dopamine D3-receptor pre-mRNA in chronic schizophrenia.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Plasma Membrane Localization and Functional Rescue of Truncated Forms of a G Protein-coupled Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Reconstitution of mutant V2 vasopressin receptors by adenovirus-mediated gene transfer. Molecular basis and clinical implication

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A Dileucine Sequence and an Upstream Glutamate Residue in the Intracellular Carboxyl Terminus of the Vasopressin V2Receptor Are Essential for Cell Surface Transport in COS.M6 Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Role of the third intracellular loop for the activation of gonadotropin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A human opsin-related gene that encodes a retinaldehyde-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

G protein-coupled receptor structure and function: the impact of disease-causing mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Diversity of G proteins in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Defects in G protein-coupled signal transduction in human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Structure and function of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Structural parts involved in activation and inactivation of the sodium channel

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Structural basis of G protein specificity of human endothelin receptors. A study with endothelinA/B chimeras

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Truncation and alanine-scanning mutants of type I adenylyl cyclase.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Construction of a high affinity zinc switch in the kappa-opioid receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Arrangement of rhodopsin transmembrane α-helices

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Binding in the growth hormone receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Functional characterization of five V2 vasopressin receptor gene mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Molecular basis of receptor/G-protein-coupling selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Heterodimerization is required for the formation of a functional GABA(B) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Deletions in the third intracellular loop of the thyrotropin receptor. A new mechanism for constitutive activation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

First intracellular loop of the human cholecystokinin-A receptor is essential for cyclic AMP signaling in transfected HEK-293 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

Three-Dimensional Structure of the Cytoplasmic Face of the G Protein Receptor Rhodopsin†

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

The First and Second Cytoplasmic Loops of the G-Protein Receptor, Rhodopsin, Independently Form β-Turns†

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2899%2900017-9

7 January 2021

10.1016/S0303-7207(99)00017-9

Identifiers

DOI

1 reference

28 July 2017

1 reference