Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention (Q33606833)

28 July 2017

title

Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention (English)

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28 July 2017

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Stetler-Stevenson WG

1

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28 July 2017

publication date

1 May 1999

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Journal of Clinical Investigation

28 July 2017

language of work or name

English

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published in

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28 July 2017

volume

103

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28 July 2017

issue

9

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28 July 2017

page(s)

1237-1241

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publication type of scholarly work

28 July 2017

review article

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Identification of the tissue inhibitor of metalloproteinases-2 (TIMP-2) binding site on the hemopexin carboxyl domain of human gelatinase A by site-directed mutagenesis. The hierarchical role in binding TIMP-2 of the unique cationic clusters of hemo

cites work

1 reference

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Matrix metalloproteinases regulate neovascularization by acting as pericellular fibrinolysins

21 June 2018

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MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

21 June 2018

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NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival

21 June 2018

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Role of Rac1 and Oxygen Radicals in Collagenase-1 Expression Induced by Cell Shape Change

21 June 2018

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Disruption of Angiogenesis by PEX, a Noncatalytic Metalloproteinase Fragment with Integrin Binding Activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408361

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

21 June 2018

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Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408361

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408361

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

21 June 2018

1 reference

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Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

21 June 2018

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The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

21 June 2018

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Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro.

21 June 2018

1 reference

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Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy

30 October 2018

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Angiostatin-converting Enzyme Activities of Human Matrilysin (MMP-7) and Gelatinase B/Type IV Collagenase (MMP-9)

10 December 2018

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12 December 2020

Kinetic Analysis of the Binding of Human Matrix Metalloproteinase-2 and -9 to Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2

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12 December 2020

Intact vitronectin induces matrix metalloproteinase-2 and tissue inhibitor of metalloproteinases-2 expression and enhanced cellular invasion by melanoma cells

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12 December 2020

Stromelysin-3 Is Induced in Tumor/Stroma Cocultures and Inactivated via a Tumor-specific and Basic Fibroblast Growth Factor-dependent Mechanism

1 reference

12 December 2020

Three-dimensional type I collagen lattices induce coordinate expression of matrix metalloproteinases MT1-MMP and MMP-2 in microvascular endothelial cells

1 reference

12 December 2020

Reduced angiogenesis and tumor progression in gelatinase A-deficient mice

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12 December 2020

Matrix metalloproteinases generate angiostatin: effects on neovascularization

1 reference

12 December 2020

Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma

1 reference

12 December 2020

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3

1 reference

12 December 2020

Tissue inhibitor of metalloproteinases‐2 inhibits bFGF‐induced human microvascular endothelial cell proliferation

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI6870

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28 July 2017

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28 July 2017

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