TNF receptor superfamily member 11b (Q3357478)

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mammalian protein found in Homo sapiens

• TNFRSF11B
• tumor necrosis factor receptor superfamily member 11B
• tumor necrosis factor receptor superfamily, member 11b
• osteoprotegerin
• osteoclastogenesis inhibitory factor

edit

Language	Label	Description	Also known as
English	TNF receptor superfamily member 11b	mammalian protein found in Homo sapiens	TNFRSF11B tumor necrosis factor receptor superfamily member 11B tumor necrosis factor receptor superfamily, member 11b osteoprotegerin osteoclastogenesis inhibitory factor

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O00300

part of

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O00300

Tumour necrosis factor receptor 11B

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O00300

Death domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine-protein kinase ephrin type A/B receptor-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

TNFR/NGFR cysteine-rich region, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O00300

encoded by

TNFRSF11B

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O00300

molecular function

cytokine activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

tumor necrosis factor-activated receptor activity

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IPI

signaling receptor activity

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

cell component

plasma membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

integral component of plasma membrane

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

extracellular region

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O00300

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

extracellular space

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

retrieved

8 April 2019

stated in

Effect of bone morphogenetic proteins-4, -5 and -6 on DNA synthesis and expression of bone-related proteins in cultured human periodontal ligament cells

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IDA

extracellular matrix

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

biological process

regulation of apoptotic process

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

skeletal system development

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

negative regulation of odontogenesis of dentin-containing tooth

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

response to nutrient

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

extracellular matrix organization

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

response to magnesium ion

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

tumor necrosis factor-mediated signaling pathway

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

response to arsenic-containing substance

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

response to estrogen

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

response to lipopolysaccharide

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

regulation of cell population proliferation

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

immune response

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

response to inorganic substance

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

apoptotic signaling pathway

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

inflammatory response

determination method

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00300&geneProductId=UniProtKB:O00300

determination method

IBA

signal transduction

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

negative regulation of bone resorption

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

apoptotic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O00300

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

regulation of signaling receptor activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00300

determination method

IEA

Gene Atlas image

PBB GE TNFRSF11B 204932 at tn.png
255 × 135; 824 bytes

1 reference

imported from Wikimedia project

English Wikipedia

exact match

https://identifiers.org/uniprot:O00300

1 reference

stated in

Identifiers.org

UniProt protein ID

O00300

reference URL

https://registry.identifiers.org/registry/uniprot

http://purl.uniprot.org/uniprot/O00300

1 reference

stated in

Identifiers.org

UniProt protein ID

O00300

reference URL

https://registry.identifiers.org/registry/uniprot

https://www.ncbi.nlm.nih.gov/protein/O00300

1 reference

stated in

Identifiers.org

UniProt protein ID

O00300

reference URL

https://registry.identifiers.org/registry/uniprot

has part(s)

Death domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O00300

tyrosine-protein kinase ephrin type A/B receptor-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O00300

TNFR/NGFR cysteine-rich region

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O00300

different from

secreted phosphoprotein 1

0 references

Identifiers

MeSH descriptor ID

D053244

subject named as

Osteoprotegerin

0 references

MeSH tree code

D12.776.543.750.705.852.760.949.249

0 references

RefSeq protein ID

NP_002537

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

4982

UniProt protein ID

O00300

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O00300

DeCS ID

52396

0 references

Ensembl protein ID

ENSP00000297350

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000297350

ENSP00000427924

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000427924

Freebase ID

/m/03_29t

0 references

Microsoft Academic ID

2780426850

0 references

OpenAlex ID

C2780426850

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

3URF

1 reference

stated in

UniProt

UniProt protein ID

O00300

retrieved

20 March 2016

language of work or name

English

UMLS CUI

C0538161

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(7 entries)

edit

• bswiki TNFRSF11B
• dewiki Osteoprotegerin
• enwiki Osteoprotegerin
• frwiki Ostéoprotégérine
• itwiki Osteoprotegerina
• ttwiki TNFRSF11B
• ukwiki TNFRSF11B

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q3357478&oldid=2022904339"