Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia (Q30665205)

10 August 2017

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia (English)

1 reference

10 August 2017

0 references

1 reference

Complement component 3

1 reference

Macrophage scavenger receptor 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Integrin alpha-M

1 reference

GOA release 2020-03-11

author name string

Hongjun Fu

1

1 reference

10 August 2017

Bin Liu

2

1 reference

10 August 2017

Jeffrey L Frost

3

1 reference

10 August 2017

Soyon Hong

4

1 reference

10 August 2017

Ming Jin

5

1 reference

10 August 2017

Beth Ostaszewski

6

1 reference

10 August 2017

Ganesh M Shankar

7

1 reference

10 August 2017

Isabel M Costantino

8

1 reference

10 August 2017

Michael C Carroll

9

1 reference

10 August 2017

Tanya N Mayadas

10

1 reference

10 August 2017

Cynthia A Lemere

11

1 reference

10 August 2017

21 March 2012

1 reference

10 August 2017

1 reference

10 August 2017

60

1 reference

10 August 2017

993-1003

1 reference

10 August 2017

6

1 reference

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Complement receptor 3 (CD11b/CD18) is implicated in the elimination of β-amyloid peptides

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Immune activation in brain aging and neurodegeneration: too much or too little?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Inflammation and microglia actions in Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Heterogeneity of microglial activation in the innate immune response in the brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Dynamics of the microglial/amyloid interaction indicate a role in plaque maintenance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Role of complement in neurodegeneration and neuroinflammation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Microglial phagocytosis of fibrillar beta-amyloid through a beta1 integrin-dependent mechanism.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

A protective role for innate immunity in systemic lupus erythematosus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Antibody-mediated phagocytosis of the amyloid beta-peptide in microglia is differentially modulated by C1q.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Effects of incorporation of immunoglobulin G and complement component C1q on uptake and degradation of Alzheimer's disease amyloid fibrils by microglia.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Complement component C1q modulates the phagocytosis of Abeta by microglia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

A novel role for the beta 2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Characterization of ameboid microglia isolated from developing mammalian brain.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Brain microglia constitutively express beta-2 integrins.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

The molecular pathology of Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325361

Scavenging of Alzheimer's amyloid beta-protein by microglia in culture.

14 July 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Absence of beta-amyloid deposits after immunization in Alzheimer disease with Lewy body dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Peripheral clearance of amyloid beta peptide by complement C3-dependent adherence to erythrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22331

3D-Reconstruction of microglia and amyloid in APP23 transgenic mice: no evidence of intracellular amyloid

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22438044

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/GLIA.22331

1 reference

10 August 2017

1 reference

10 August 2017

1 reference