Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model (Q30421540)

10 August 2017

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model (English)

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10 August 2017

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endoplasmic reticulum

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Sarah A Tersey

1

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Raghavendra Mirmira

10

object named as

Raghavendra G Mirmira

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10 August 2017

Carmella Evans-Molina

7

object named as

Carmella Evans-Molina

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10 August 2017

5

Natalie D Stull

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10 August 2017

3

Andrew T Templin

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10 August 2017

Yurika Nishiki

2

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10 August 2017

Susanne M Cabrera

4

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10 August 2017

Stephanie C Colvin

6

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10 August 2017

Jenna L Rickus

8

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10 August 2017

Bernhard Maier

9

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10 August 2017

language of work or name

English

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publication date

1 April 2012

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10 August 2017

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10 August 2017

61

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10 August 2017

818-827

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10 August 2017

4

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

10 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes

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How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited

20 June 2018

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Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

20 June 2018

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Inhibition of deoxyhypusine synthase enhances islet {beta} cell function and survival in the setting of endoplasmic reticulum stress and type 2 diabetes

20 June 2018

1 reference

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Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

20 June 2018

1 reference

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Immune cell crosstalk in type 1 diabetes

20 June 2018

1 reference

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The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice

20 June 2018

1 reference

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

20 June 2018

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Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

20 June 2018

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Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset

20 June 2018

1 reference

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Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

20 June 2018

1 reference

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Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells

20 June 2018

1 reference

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Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

20 June 2018

1 reference

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Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

20 June 2018

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Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes

20 June 2018

1 reference

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The role of nitric oxide and the unfolded protein response in cytokine-induced beta-cell death

20 June 2018

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Signal integration in the endoplasmic reticulum unfolded protein response

20 June 2018

1 reference

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Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells

20 June 2018

1 reference

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Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets

20 June 2018

1 reference

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Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.

20 June 2018

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Coping with stress: eIF2 kinases and translational control

20 June 2018

1 reference

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Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes

20 June 2018

1 reference

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

The endoplasmic reticulum Ca2+ store: a view from the lumen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

What is the concentration of calcium ions in the endoplasmic reticulum?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

The non-obese diabetic (NOD) mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA)-2b and -3.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314371

Abnormalities in dendritic cell and macrophage accumulation in the pancreas of nonobese diabetic (NOD) mice during the early neonatal period

26 November 2018

1 reference

12 December 2020

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse

1 reference

12 December 2020

Phosphorylation of the alpha-subunit of the eukaryotic initiation factor-2 (eIF2alpha) reduces protein synthesis and enhances apoptosis in response to proteasome inhibition

1 reference

12 December 2020

Methods for analyzing eIF2 kinases and translational control in the unfolded protein response

1 reference

12 December 2020

Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells

1 reference

12 December 2020

CHOP deletion does not impact the development of diabetes but suppresses the early production of insulin autoantibody in the NOD mouse

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB11-1293

1 reference

10 August 2017

1 reference

10 August 2017

1 reference