The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl (Q30167736)

9 June 2017

title

The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl (English)

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9 June 2017

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Robert L Geahlen

4

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author name string

Ibrahim Y Hawash

1

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9 June 2017

Kamala P Kesavan

2

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9 June 2017

Anthony I Magee

3

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9 June 2017

Marietta L Harrison

5

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9 June 2017

publication date

10 December 2001

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Journal of Biological Chemistry

9 June 2017

language of work or name

English

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number of pages

9

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based on heuristic

inferred from page(s)

published in

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9 June 2017

volume

277

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9 June 2017

issue

7

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9 June 2017

page(s)

5683-5691

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Cellular functions regulated by Src family kinases

9 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Profound block in thymocyte development in mice lacking p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The role of lipid rafts in T cell antigen receptor (TCR) signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Palmitoylation of either Cys-3 or Cys-5 is required for the biological activity of the Lck tyrosine protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

A pivotal role of cysteine 3 of Lck tyrosine kinase for localization to glycolipid-enriched microdomains and T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Functional rafts in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Localization of LAT in glycolipid-enriched microdomains is required for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Membrane Compartmentation Is Required for Efficient T Cell Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The amplification of TCR signaling by dynamic membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Microdomains in lymphocyte signalling: beyond GPI-anchored proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Ras GTPase-activating protein: a substrate and a potential binding protein of the protein-tyrosine kinase p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Association between mitogen-activated protein kinase and the zeta chain of the T cell receptor (TcR) with the SH2,3 domain of p56lck. Differential regulation by TcR cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Rapid T-cell receptor-mediated tyrosine phosphorylation of p120, an Fyn/Lck Src homology 3 domain-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The Cbl protooncoprotein: a negative regulator of immune receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Cbl: complex formation and functional implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The Cbl proto-oncogene product negatively regulates the Src-family tyrosine kinase Fyn by enhancing its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Enrichment of G-protein palmitoyltransferase activity in low density membranes: in vitro reconstitution of Galphai to these domains requires palmitoyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Pseudo-enzymatic S-acylation of a myristoylated Yes protein tyrosine kinase peptide in vitro may reflect non-enzymatic S-acylation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Reversible palmitoylation of signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Activation and depalmitoylation of Gs alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110002200

21 January 2018

Identifiers

DOI

10.1074/JBC.M110002200

1 reference

9 June 2017

1 reference