Protein lin-12 CELE_R107.8 (Q29805244)

Growth factor receptor cysteine-rich domain superfamily

1 reference

Ankyrin repeat-containing domain superfamily

1 reference

Notch, NODP domain, protein family

1 reference

Notch proteins

1 reference

Notch, NOD domain, protein family

1 reference

Ankyrin repeat-containing domain, protein family

1 reference

EGF-like calcium-binding domain, protein family

1 reference

EGF-like domain, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

EGF-like calcium-binding, conserved site, protein family

1 reference

Ankyrin repeat, protein family

1 reference

transmembrane signaling receptor activity

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

ISS

1 reference

1 January 2018

The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

ISS

calcium ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 reference

1 January 2018

IEA

protein binding

5 references

1 January 2018

LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 January 2018

OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 January 2018

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 January 2018

Protein interaction mapping in C. elegans using proteins involved in vulval development

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 January 2018

sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 reference

1 January 2018

RNA polymerase II transcription regulator complex

IEA

IDA

1 reference

1 January 2018

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

nematode larval development

IDA

biological process

1 reference

1 January 2018

Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

oviposition

1 reference

1 January 2018

Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

vulval development

regulation of mesodermal cell fate specification

dauer exit

1 reference

1 January 2018

Notch signalling is required for both dauer maintenance and recovery in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

cell-cell signaling involved in cell fate commitment

1 reference

1 January 2018

Cell autonomy of lin-12 function in a cell fate decision in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

positive regulation of mesodermal cell fate specification

1 reference

1 January 2018

TheC. elegansSoxC protein SEM-2 opposes differentiation factors to promote a proliferative blast cell fate in the postembryonic mesoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14585

1 reference

EGF-like calcium-binding, conserved site

1 reference

Notch, NOD domain

1 reference

EGF-like domain

1 reference

ankyrin repeat

1 reference

EGF-like, conserved site

1 reference

Notch, NODP domain

1 reference

ankyrin repeat-containing domain

1 reference

EGF-like calcium-binding domain

1 reference

EGF-type aspartate/asparagine hydroxylation site

1 reference