ARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated Adhesion (Q28854571)

28 February 2017

title

ARAP, a Novel Adaptor Protein, Is Required for TCR Signaling and Integrin-Mediated Adhesion (English)

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28 February 2017

main subject

FYN binding protein 2

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T cell receptor signaling pathway

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Seung Hee Jung

1

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28 February 2017

Eun Hye Yoo

2

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28 February 2017

Mi Jin Yu

3

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28 February 2017

Hyeon Myeong Song

4

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28 February 2017

Hee Yoon Kang

5

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28 February 2017

Je-Yoel Cho

6

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28 February 2017

Jong Ran Lee

7

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28 February 2017

publication date

1 August 2016

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28 February 2017

language of work or name

English

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published in

Journal of Immunology

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28 February 2017

volume

197

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28 February 2017

issue

3

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28 February 2017

page(s)

942–952

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The immunological synapse: a molecular machine controlling T cell activation

28 February 2017

cites work

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T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

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Three-dimensional segregation of supramolecular activation clusters in T cells

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Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

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Lipid rafts and signal transduction

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Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells

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TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

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The cellular context of T cell signaling

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Integration of T cell receptor-dependent signaling pathways by adapter proteins

21 January 2018

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Adaptors and molecular scaffolds in immune cell signaling

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Identification of putative serum glycoprotein biomarkers for human lung adenocarcinoma by multilectin affinity chromatography and LC-MS/MS.

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Identification of diabetic nephropathy‐selective proteins in human plasma by multi‐lectin affinity chromatography and LC‐MS/MS

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Coupling of the TCR to integrin activation by Slap-130/Fyb.

21 January 2018

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The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.

21 January 2018

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Electroporation in ‘intracellular’ buffer increases cell survival

21 January 2018

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Association of the Src homology 2 domain-containing leukocyte phosphoprotein of 76 kD (SLP-76) with the p85 subunit of phosphoinositide 3-kinase

21 January 2018

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Role of Two Adaptor Molecules SLP-76 and LAT in the PI3K Signaling Pathway in Activated T Cells

21 January 2018

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Competition between SLP76 and LAT for PLCγ1 binding in resting T cells

21 January 2018

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Functional association between SLAP-130 and SLP-76 in Jurkat T cells

21 January 2018

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FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

21 January 2018

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ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation

21 January 2018

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Identification of a putative regulator of early T cell activation genes

21 January 2018

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The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1

21 January 2018

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T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes

21 January 2018

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PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells

21 January 2018

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ADAP-ting TCR signaling to integrins

21 January 2018

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SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion

21 January 2018

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Functional Cooperation between the Proteins Nck and ADAP Is Fundamental for Actin Reorganization

21 January 2018

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Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1.

21 January 2018

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Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production

21 January 2018

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Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells

21 January 2018

1 reference

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Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion

21 January 2018

1 reference

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SKAP‐HOM, a novel adaptor protein homologous to the FYN‐associated protein SKAP551

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1501913

FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4049%2FJIMMUNOL.1501913

The Actin Cytoskeleton and Lymphocyte Activation

21 January 2018

1 reference

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Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.4049/JIMMUNOL.1501913

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28 February 2017

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