A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs (Q28646569)

3 February 2017

title

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs (English)

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3 February 2017

main subject

proto-oncogene protein

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1439791

reference URL

26 September 2022

author name string

M. J. Hart

1

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3 February 2017

Y. Maru

2

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3 February 2017

D. Leonard

3

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3 February 2017

O. N. Witte

4

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3 February 2017

T. Evans

5

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3 February 2017

R. A. Cerione

6

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3 February 2017

publication date

30 October 1992

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3 February 2017

language of work or name

0 references

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3 February 2017

volume

258

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3 February 2017

issue

5083

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3 February 2017

page(s)

812–815

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Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

3 February 2017

cites work

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The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization

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Regulation of reversible binding of smg p25A, a ras p21-like GTP-binding protein, to synaptic plasma membranes and vesicles by its specific regulatory protein, GDP dissociation inhibitor

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Purification and characterization of a third cytosolic component of the superoxide-generating NADPH oxidase of macrophages

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ras genes

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Bcr encodes a GTPase-activating protein for p21rac

0 references

Isolation of a new human oncogene from a diffuse B-cell lymphoma.

0 references

Stimulation of p21 ras upon T-cell activation

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Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

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Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins.

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Signal transduction through small GTPases—A tale of two GAPs

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Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene

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Identification of the human platelet GTPase activating protein for the CDC42Hs protein

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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

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Structural organization of the bcr gene and its role in the Ph' translocation

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Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins

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vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

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Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

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The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein

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BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr

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Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

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A cytoplasmic protein inhibits the GTPase activity of H-Ras in a phospholipid-dependent manner

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Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein

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Identifiers

DOI

10.1126/SCIENCE.1439791

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1 reference