Diphtheria toxin: mode of action and structure (Q28646284)

3 February 2017

title

Diphtheria toxin: mode of action and structure (English)

1 reference

3 February 2017

R. J. Collier

1

1 reference

3 February 2017

publication date

1 March 1975

1 reference

3 February 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=164179

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/164179/?tool=EBI

16 May 2022

work available at URL

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A164179

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/164179/pdf/?tool=EBI

16 May 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A164179

https://europepmc.org/articles/PMC413884

16 May 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A164179

https://europepmc.org/articles/PMC413884?pdf=render

16 May 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A164179

https://journals.asm.org/doi/pdf/10.1128/br.39.1.54-85.1975

16 May 2022

1 reference

10.1128/BR.39.1.54-85.1975

Crossref

DOI

https://api.crossref.org/works/10.1128/BR.39.1.54-85.1975

16 May 2022

published in

Bacteriological Reviews

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3 February 2017

volume

39

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3 February 2017

issue

1

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3 February 2017

page(s)

54–85

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publication type of scholarly work

3 February 2017

review article

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Studies on the virulence of bacteriophage-infected strains of Corynebacterium diphtheriae

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Structure and activity of diphtheria toxin. I. Thiol-dependent dissociation of a fraction of toxin into enzymically active and inactive fragments

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Partial characterization of diphtheria toxin and its subunits

17 March 2017

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Adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis by diphtheria toxin

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Competitive binding of adenine and nicotinamide-adenine dinucleotide to diphtheria toxin.

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Specificity of diphtheria toxin action on heart and muscle tissues of Guinea pigs

3 June 2018

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3 June 2018

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An early effect of diphtheria toxin on the metabolism of mammalian cells growing in culture

3 June 2018

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3 June 2018

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The effect of diphtheria toxin on the metabolism of HeLa cells

3 June 2018

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3 June 2018

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The action of diphtheria toxin on tissue cultures and its neutralization by antitoxin.

3 June 2018

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Some effects of iron deficiency on the extracellular products released by toxigenic and nontoxigenic strains of Corynebacterium diphtheriae.

3 June 2018

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A new culture method designed for kinetic studies on diphtheria toxin production.

3 June 2018

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Genetic factors in Corynebacterium diphtheriae conversion

3 June 2018

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Evidence for the active role of bacteriophage in the conversion of nontoxigenic Corynebacterium diphtheriae to toxin production

3 June 2018

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Phage-host relationships in nontoxigenic and toxigenic diphtheria bacilli

3 June 2018

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Evidence for the induced nature of the change from nontoxigenicity to toxigenicity in Corynebacterium diphtheriae as a result of exposure to specific bacteriophage.

3 June 2018

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Studies on the mode of action of diphtheria toxin. II. Protein synthesis in primary heart cell cultures

3 June 2018

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Studies on the mode of action of diphtheria toxin. I. Protein synthesis in guinea pig tissues

3 June 2018

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In Vitro Inhibition of Diphtheria Toxin Action by Ammonium Salts and Amines

3 June 2018

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Mode of Inhibition of Diphtheria Toxin by Ammonium Chloride

3 June 2018

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Activity of diphtheria toxin. II. Early events in the intoxication of HeLa cells

3 June 2018

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Response of Cultured Mammalian Cells to Diphtheria Toxin III. Inhibition of Protein Synthesis Studied at the Subcellular Level

3 June 2018

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An epidemic of diphtheria carriers

3 June 2018

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3 June 2018

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3 June 2018

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Diphtheria toxin: Requirement for active protein synthesis for inactivation of aminoacyl transferase II in the intact mammalian cell

3 June 2018

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Studies on the mode of action of diphtheria toxin. III. Effect on subcellular components of protein synthesis from the tissues of intoxicated guinea pigs and rats

3 June 2018

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The response of cultured mammalian cells to diphtheria toxin. I. Amino acid transport, accumulation, and incorporation in normal and intoxicated sensitive cells

3 June 2018

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Reversion of toxicity of diphtheria toxoid

3 June 2018

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Response of Interferon-Treated Cells to Diphtheria Toxin

3 June 2018

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Translation: its mechanism and control

3 June 2018

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Mutation in the structural gene for diphtheria toxin carried by temperate phage .

3 June 2018

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Park-Williams number 8 strain of Corynebacterium diphtheriae

3 June 2018

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Genetic Analysis of tox + and tox − Bacteriophages of Corynebacterium diphtheriae

3 June 2018

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Separation of mitochondrial and cytoplasmic peptide chain elongation factors from yeast

3 June 2018

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Isolation and Characterization of Clostridium botulinum Type B Toxin

3 June 2018

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Mechanism of action of the toxic lectins abrin and ricin

3 June 2018

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Studies on the mode of action of diphtheria toxin. V. Protein metabolism in a guinea pig model simulating chronic diphtheritic toxemia

3 June 2018

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Affinity chromatography and structural analysis of Vibrio cholerae enterotoxin-ganglioside agarose and the biological effects of ganglioside-containing soluble polymers

3 June 2018

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Gangliosides and membrane receptors for cholera toxin

3 June 2018

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Interaction of Vibrio cholerae enterotoxin with cell membranes

3 June 2018

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Different biological properties of the two constituent peptide chains of ricin a toxic protein inhibiting protein synthesis

3 June 2018

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Disulfide-Toxicity Relationship of Botulinal Toxin Types A, E, and F

3 June 2018

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Toxic proteins inhibiting protein synthesis

3 June 2018

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Inhibition of protein synthesis after intravenous or intramuscular challenge with diphtheria toxin

3 June 2018

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Response of cultured mammalian cells to diphtheria toxin. IV. Isolation of KB cells resistant to diphtheria toxin

3 June 2018

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Characteristics of human antibody to diphtheria toxin.

3 June 2018

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Studies on the Mode of Action of Diphtheria Toxin VI. Inhibition of Protein Synthesis Induced by Local Infection with Toxinogenic Corynebacterium diphtheriae

3 June 2018

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Intracellular protein degradation in mammalian and bacterial cells

3 June 2018

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Selective Toxicity of Diphtheria Toxin for Malignant Cells

3 June 2018

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Binding of nicotinamide-adenine dinucleotides to diphtheria toxin

3 June 2018

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Chemical structure of a modification of the Escherichia coli ribonucleic acid polymerase alpha polypeptides induced by bacteriophage T4 infection.

3 June 2018

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Elongation factor 2. Amino acid sequence at the site of adenosine diphosphate ribosylation

3 June 2018

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Enzymatic ADP-ribosylation of proteins and regulation of cellular activity

3 June 2018

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Poly(adenosine diphosphate ribose).

3 June 2018

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The elongation factor 2 content of mammalian cells. Assay method and relation to ribosome number.

3 June 2018

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Response of cultured mammalian cells to diphtheria toxin. V. Concurrent resistance to ribonucleic acid viruses in diphtheria toxin-resistant KB cell strains.

3 June 2018

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Interaction of ADP-ribosylated aminoacyl-transferase II with GTP and with ribosomes

3 June 2018

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Binding of transfer factor II to ribosomal RNA and inhibition of the binding by guanosine nucleotides

3 June 2018

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Corynebacterium diphtheriae and its relatives.

3 June 2018

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Inhibitory effect of diphtheria toxin on amino acid incorporation in Escherichia coli cell-free system

3 June 2018

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Inhibition of peptide chain elongation in a cell-free system from yeast by pre-incubation of the yeast peptidyl-translocase with diphtheria toxin and NAD.

3 June 2018

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A proposed mechanism for ADP ribosylation of aminoacyl transferase II by diphtheria toxin

3 June 2018

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Studies on transferase II using diphtheria toxin

3 June 2018

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Alteration in the ionic properties of aminoacyltransferase II from rat liver by NAD+ and diphtheria toxin

3 June 2018

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Characteristics of the reaction between diphtheria toxin, pyridine coenzymes and the GTP-splitting transfer factor FI.

3 June 2018

1 reference

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Studies on the mode of action of diphtheria toxin. VII. Toxin-stimulated hydrolysis of nicotinamide adenine dinucleotide in mammalian cell extracts

3 June 2018

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Interaction of aminoacyl transferase II and guanosine triphosphate: inhibition by diphtheria toxin and nicotinamide adenine dinucleotide

3 June 2018

1 reference

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Site in cell-free protein synthesis sensitive to diphtheria toxin

3 June 2018

1 reference

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Studies on the mode of action of diphtheria toxin. VI. Site of the action of toxin in living cells

3 June 2018

1 reference

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Studies on the mode of action of diphtheria toxin. V. Inhibition of peptide bond formation by toxin and NAD in cell-free systems and its reversal by nicotinamide

3 June 2018

1 reference

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Studies on the mode of action of diphtheria toxin. IV. Specificity of the cofactor (NAD) requirement for toxin action in cell-free systems

3 June 2018

1 reference

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Studies on the mode of action of diphtheria toxin. 3. Site of toxin action in cell-free extracts

3 June 2018

1 reference

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Studies of the activity of diphtheria toxin. I. Poliovirus replication in intoxicated HeLa cells

3 June 2018

1 reference

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Specific reversal of diphtheria toxin mediated inhibition of protein synthesis in guinea pig tissues

3 June 2018

1 reference

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Synthesis of diphtheria tox-gene products in Escherichia coli extracts

3 June 2018

1 reference

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Diphtheria toxin and related proteins. 3. Reconstitution of hybrid "diphtheria toxin" from nontoxic mutant proteins

3 June 2018

1 reference

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Diphtheria toxin and related proteins. I. Isolation and properties of mutant proteins serologically related to diphtheria toxin

3 June 2018

1 reference

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Action of denaturing aents on diphtERIA TOXIN

3 June 2018

1 reference

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The response of cultured mammalian cells to diphtheria toxin. II. The resistant cell: enhancement of toxin action by poly-L-ornithine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Diphtheria toxin, protein synthesis, and the cell

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

An immunological study of the diphtheria toxin molecule

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Inhibition of growth of Erlich tumors in Swiss mice by diphtheria toxin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Interaction of transferase II with the 60 s ribosomal subunit.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Aminoacyltransferase II from rat liver. II. Some physical and chemical properties of the purified enzyme and its adenosine diphosphate ribose derivative.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Reconstitution of diphtheria toxin from two nontoxic cross-reacting mutant proteins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Effect of diphtheria toxin on protein synthesis: inactivation of one of the transfer factors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413884

Interaction of fragment A from diphtheria toxin with nicotinamide adenine dinucleotide

27 November 2018

1 reference

12 December 2020

The formation of a ternary complex between diphtheria toxin, aminoacyltransferase II, and diphosphopyridine nucleotide

1 reference

12 December 2020

Formation of a complex involving ADP-ribosylated human translocation factor, guanosine nucleotide and ribosomes

1 reference

12 December 2020

Formation of heavy diphtheria toxin

1 reference

12 December 2020

Modification of diphtheria toxin by NAD

1 reference

12 December 2020

Virulence, toxinogeny, and lysogeny in Corynebacterium diphtheriae

1 reference

12 December 2020

Diphtheria toxin subunit active in vitro

1 reference

12 December 2020

Diphtheria Toxin: Specific Competition for Cell Receptors

1 reference

12 December 2020

Purification of diphtheria toxin. II. The isolation of crystalline toxin-protein and some of its properties

1 reference

12 December 2020

A common subunit structure in Clostridium botulinum type A, B and E toxins

1 reference

12 December 2020

The inhibitory effect of diphtheria toxin on amino acid incorporation by a bacterial cell-free system

1 reference

12 December 2020

Studies on the peptidyl tRNA translocase from rat liver

1 reference

12 December 2020

Nucleotide binding of diphtheria toxin and its fragment A

1 reference

12 December 2020

Enzyme treatment of KB cells: the altered effect of diphtheria toxin

1 reference

12 December 2020

Diphtheria toxin-dependent adenosine diphosphate ribosylation of aminoacyl transferase II and inhibition of protein synthesis

1 reference

12 December 2020

Fluorescence studies of nucleotides binding to diphtheria toxin and its fragment A

1 reference

12 December 2020

The diphtheria toxin-dependent adenosine diphosphate ribosylation of rat liver aminoacyl transferase. II. General characteristics and mechanism of the reaction

1 reference

12 December 2020

Studies on diphtheria toxin. The effect of GTP on the toxin-dependent adenosine diphosphate ribosylation of rat liver aminoacyl transferase. II

1 reference

12 December 2020

Diphtheria in the United States, 1959-1970

1 reference

12 December 2020

Action of diphtheria toxin on cells cultivated in vitro

1 reference

12 December 2020

Interaction of transferase II with polynucleotides and inhibition of the interaction by guanosine nucleotides

1 reference

12 December 2020

New form of diphtheria toxin

1 reference

12 December 2020

Alterations in the level of muscle phosphocreatine of guinea pigs produced by the injection of diphtheria toxin

1 reference

12 December 2020

Structure and activity of diphtheria toxin. II. Attack by trypsin at a specific site within the intact toxin molecule

1 reference

12 December 2020

Structure-Activity Relationships in Diphtheria Toxin

1 reference

12 December 2020

The influence of toxaemia on carbohydrate metabolism

1 reference

12 December 2020

ATTEMPT AT DEMONSTRATION OF DISULFIDE BONDS IN TETANUS TOXIN AND DIPHTHERIA TOXIN

1 reference

12 December 2020

Demonstration of tyrosine in the enzymatic site of diphtheria toxin

1 reference

12 December 2020

Adenosine diphosphoribosylation of aminoacyl transferase II by diphtheria toxin

1 reference

12 December 2020

Estimate of myocardial damage induced by diphtheria toxin

1 reference

12 December 2020

Antibody to lactate dehydrogenase. V. Use as a carrier for introducing diphtheria toxin into mouse tumor cells

1 reference

12 December 2020

AMINO ACID COMPOSITION OF PURIFIED DIPHTHERIA TOXIN

1 reference

12 December 2020

Inactivation of aminoacyl transferase II by diphtheria toxin

1 reference

12 December 2020

1 reference

12 December 2020

Synthesis of diphtheria toxin in E. coli cell-free lysate

1 reference

12 December 2020

Chemical properties of elongation factor 2. Amino acid composition, NH 2 -terminal residue, and sulfhydryl reactivity

1 reference

12 December 2020

[Relations between the structure of diphtheric toxin and anatoxin]

1 reference

12 December 2020

Cell culture reactivity to diphtheria, Staphylococcus, tetanus and Escherichia coli toxins

1 reference

12 December 2020

Selective destruction of target cells by diphtheria toxin conjugated to antibody directed against antigens on the cells

1 reference

12 December 2020

Diphtheria toxin and related proteins. II. Kinetic studies on intoxication of HeLa cells by diphtheria toxin and related proteins

1 reference

12 December 2020

Diphtheria toxin: Evidence for presence of fragment B in corynebacteriophage

1 reference

12 December 2020

1 reference

12 December 2020

Expression of diphtheria toxin genes carried by integrated and nonintegrated phage beta

1 reference

12 December 2020

Observations on the Structure of Diphtheria Toxin

1 reference

12 December 2020

10.1128/BR.39.1.54-85.1975

Identifiers

DOI

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=164179

19 December 2022

PMC publication ID

413884

0 references

1 reference