Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools (Q28511162)

GOA release 2020-03-11

Hirofumi Arakawa

6

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author name string

Takashi Kimura

1

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25 January 2017

Satoshi Takeda

2

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25 January 2017

Yoji Sagiya

3

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25 January 2017

Mitsukazu Gotoh

4

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25 January 2017

Yusuke Nakamura

A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

5

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25 January 2017

language of work or name

English

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publication date

1 August 2003

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25 January 2017

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25 January 2017

34

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25 January 2017

440–445

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25 January 2017

4

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25 January 2017

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p53 sends nucleotides to repair DNA.

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Ribonucleotide reductases

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The DNA damage response: putting checkpoints in perspective

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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WAF1, a potential mediator of p53 tumor suppression

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

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Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

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Recent advances in the protocols of transgenic mouse mutation assays.

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Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase

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Identification and isolation of the gene encoding the small subunit of ribonucleotide reductase from Saccharomyces cerevisiae: DNA damage-inducible gene required for mitotic viability

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7 January 2021

DNA damage induction of ribonucleotide reductase

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7 January 2021

Identification of the DNA damage-responsive element of RNR2 and evidence that four distinct cellular factors bind it

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7 January 2021

Surfing the p53 network

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7 January 2021

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

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7 January 2021

Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers

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7 January 2021