Functional profiling of live melanoma samples using a novel automated platform (Q28484649)

9

object named as

Adina Vultur

0 references

Clemens Krepler

8

object named as

Clemens Krepler

0 references

Lynn Schuchter

12

object named as

Lynn Schuchter

0 references

author name string

Adam Schayowitz

1

0 references

Greg Bertenshaw

2

0 references

Emiko Jeffries

3

0 references

Timothy Schatz

4

0 references

James Cotton

5

0 references

Jessie Villanueva

6

0 references

Wei Xu

10

0 references

Gordon H Yu

11

0 references

Douglas P Clark

Creative Commons Attribution 4.0 International

13

0 references

publication date

2012

0 references

language of work or name

0 references

0 references

7

0 references

issue

12

0 references

page(s)

e52760

0 references

copyright license

start time

28 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3532357/fullTextXML

inferred from PubMed Central ID database lookup

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

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Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

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From genes to drugs: targeted strategies for melanoma

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EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF-Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib

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Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance

29 September 2017

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Combinations of BRAF, MEK, and PI3K/mTOR Inhibitors Overcome Acquired Resistance to the BRAF Inhibitor GSK2118436 Dabrafenib, Mediated byNRASorMEKMutations

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PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

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Hyperactivation of MEK–ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells

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Identifiers

DOI

10.1371/JOURNAL.PONE.0052760

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

5128193

ADS bibcode

2012PLoSO...752760S

0 references

OpenCitations bibliographic resource ID

5128193

1 reference