The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin (Q28344558)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10944112%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

The protein kinase PKR is required for p38 MAPK activation and the innate immune response to bacterial endotoxin (English)

1 reference

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9 November 2019

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3

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9 November 2019

author name string

K C Goh

series ordinal

1

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9 November 2019

M J deVeer

series ordinal

2

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9 November 2019

publication date

1 August 2000

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9 November 2019

language of work or name

0 references

1 reference

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9 November 2019

volume

19

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9 November 2019

issue

16

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9 November 2019

page(s)

4292-4297

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How cells respond to interferons

9 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

20 March 2017

1 reference

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

20 March 2017

1 reference

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

20 March 2017

1 reference

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Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells

20 March 2017

1 reference

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Innate Immunity: The Virtues of a Nonclonal System of Recognition

20 March 2017

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Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

7 April 2017

1 reference

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

7 April 2017

1 reference

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

7 April 2017

1 reference

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The p38 signal transduction pathway: activation and function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

29 September 2017

1 reference

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JNK2 and IKKbeta are required for activating the innate response to viral infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Activation of p38 mitogen-activated protein kinase and c-Jun NH(2)-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

The stress-activated protein kinase pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Overexpression of RelA causes G1 arrest and apoptosis in a pro-B cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase

29 September 2017

1 reference

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The role of interleukin 6 in endotoxin-induced inflammatory responses

29 September 2017

1 reference

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Lipopolysaccharide (LPS)-induced IL-6 production by embryonic fibroblasts isolated and cloned from LPS-responsive and LPS-hyporesponsive mice

2 June 2018

1 reference

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Regulation of NF-kappa B activation by MAP kinase cascades.

2 June 2018

1 reference

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The Double-Stranded RNA-Dependent Protein Kinase PKR: Structure and Function

2 June 2018

1 reference

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Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=302024

Induction of E-Selectin Expression by Double-Stranded RNA and TNF- Is Attenuated in Murine Aortic Endothelial Cells Derived from Double-Stranded RNA-Activated Kinase (PKR)-Null Mice

2 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10944112

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The interrelation between TNF, IL-6, and PAF secretion induced by LPS in an in vivo and in vitro murine model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10944112

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/EMBOJ/19.16.4292

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10944112%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10944112%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

10944112

2 references