All oxygens in nucleic acids react with carcinogenic ethylating agents (Q28335578)

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13 August 2022

nitrosourea compound

1 reference

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13 August 2022

N-ethyl-N-nitrosourea

1 reference

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13 August 2022

nucleic acids

1 reference

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13 August 2022

carcinogen

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13 August 2022

author name string

B. Singer

series ordinal

1

1 reference

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Specificity of different classes of ethylating agents toward various sites in RNA

13 August 2022

publication date

25 November 1976

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language of work or name

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264

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issue

5584

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page(s)

333-9

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cites work

1 reference

https://api.crossref.org/works/10.1038/264333A0

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

21 April 2017

1 reference

Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels

21 January 2018

1 reference

Reaction products from N-methyl-N-nitrosourea and deoxyribonucleic acid containing thymidine residues. Synthesis and identification of a new methylation product, O4-methylthymidine

21 January 2018

1 reference

The nature of single-strand breaks in DNA following treatment of L-cells with methylating agents

21 January 2018

1 reference

Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues

21 January 2018

1 reference

Chemical carcinogenesis in the nervous system. Preferential accumulation of O6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of N-methyl-N-nitrosourea

21 January 2018

1 reference

Specificity of different classes of ethylating agents toward various sites of HeLa cell DNA in vitro and in vivo

21 January 2018

1 reference

O2-alkylcytidine - - a new major product of neutral, aqueous reaction of cytidine with carcinogens

21 January 2018

1 reference

Methylation and ethylation of uridylic acid and thymidylic acid. Reactivity of the ring and phosphate as a function of pH and alkyl group

21 January 2018

1 reference

Reaction of diazoalkanes with 1-substituted 2, 4-dioxopyrimidines. Formation of O2, N-3 and O4-alkyl products

21 January 2018

1 reference

Inactivation of viruses and cells by mustard gas.

21 January 2018

1 reference

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

21 January 2018

1 reference

Exhaustion and recovery of repair excision of O6-methylguanine from rat liver DNA

21 January 2018

1 reference

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

21 January 2018

1 reference

7 January 2021

Alkylation of rat brain nucleic acids by N-methyl-N-nitrosourea and methyl methanesulphonate

1 reference

7 January 2021

Reaction of guanosine with ethylating agents

1 reference

7 January 2021

Reaction of cytidine with ethylating agents

1 reference

7 January 2021

Reaction of adenosine with ethylating agents

1 reference

7 January 2021

Chemical Production of Mutations

1 reference

7 January 2021

The properties of O 6 -methylguanine in templates for RNA polymerase

1 reference

7 January 2021

The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine

1 reference

7 January 2021

The enzymatic release of O6-methylguanine and 3-methyladenine from DNA reacted with the carcinogen N-methyl-N-nitrosourea

1 reference

7 January 2021

Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

1 reference

7 January 2021

Effects of alkylation of phosphodiesters and of bases of infectivity and stability of tobacco mosaic virus RNA

1 reference

7 January 2021

1 reference

7 January 2021

Dimensions Publication ID

Identifiers

DOI

10.1038/264333A0

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1010450196

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