Signals from within: the DNA-damage-induced NF-kappaB response (Q28291658)

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

Europe PubMed Central

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Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

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The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

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The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

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A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

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Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

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Ikappa Balpha is a target for the mitogen-activated 90kDa ribosomal S6 kinase

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The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

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Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus

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IkappaB kinases: key regulators of the NF-kappaB pathway

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

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UVB light induces nuclear factor kappa B (NF kappa B) activity independently from chromosomal DNA damage in cell-free cytosolic extracts

21 January 2018

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NF-κB Activation Mediates Doxorubicin-induced Cell Death in N-type Neuroblastoma Cells

21 January 2018

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Activation of nuclear factor-kappaB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide

21 January 2018

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Evidence that reactive oxygen species do not mediate NF-kappaB activation

21 January 2018

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Ionizing radiation and short wavelength UV activate NF-κB through two distinct mechanisms

21 January 2018

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Nuclear factor – κB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug

21 January 2018

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N-acetyl-L-cysteine inhibits 26S proteasome function: implications for effects on NF-kappaB activation

21 January 2018

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Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

21 January 2018

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Cyclobutane pyrimidine dimers in UV-DNA induce release of soluble mediators that activate the human immunodeficiency virus promoter.

21 January 2018

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Sequential DNA damage-independent and -dependent activation of NF-kappa B by UV

21 January 2018

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Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells

21 January 2018

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NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events

21 January 2018

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Topoisomerase II is required for mitoxantrone to signal nuclear factor kappa B activation in HL60 cells.

21 January 2018

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DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

21 January 2018

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A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-kappaB.

21 January 2018

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ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

21 January 2018

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The ATM protein is required for sustained activation of NF-kappaB following DNA damage

21 January 2018

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Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation

21 January 2018

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ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage

21 January 2018

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Circumvention of nuclear factor kappaB-induced chemoresistance by cytoplasmic-targeted anthracyclines

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The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

21 January 2018

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The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

21 January 2018

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CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

21 January 2018

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Expression of the cDNA for the beta subunit of human casein kinase II confers partial UV resistance on xeroderma pigmentosum cells

21 January 2018

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p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1.

21 January 2018

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Transcriptional cross talk between NF-kappaB and p53.

21 January 2018

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Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

21 January 2018

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ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

21 January 2018

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Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

21 January 2018

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Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells

21 January 2018

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Modulation of NF-kappaB activity by exchange of dimers

21 January 2018

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The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

21 January 2018

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Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

21 January 2018

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p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1.

21 January 2018

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NF-kappaB: tumor promoter or suppressor?

21 January 2018

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Role of NF-κB in p53-mediated programmed cell death

21 January 2018

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p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

21 January 2018

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Is NF-kappaB the sensor of oxidative stress?

21 January 2018

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7 January 2021

Induction of nuclear factor kappa B after low-dose ionizing radiation involves a reactive oxygen intermediate signaling pathway

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7 January 2021

The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus

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7 January 2021

Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells

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7 January 2021

Cellular and molecular responses to topoisomerase I poisons. Exploiting synergy for improved radiotherapy

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7 January 2021

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

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7 January 2021

The DNA-dependent protein kinase

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7 January 2021

Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium

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7 January 2021

Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations

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7 January 2021

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7 January 2021

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

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7 January 2021

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

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7 January 2021

Reciprocal inhibition of p53 and nuclear factor-kappaB transcriptional activities determines cell survival or death in neurons.

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7 January 2021

PIDD mediates NF-kappaB activation in response to DNA damage

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7 January 2021