Solution Structure of FKBP, a Rotamase Enzyme and Receptor for FK506 and Rapamycin (Q28273170)

DOI

10.1126/SCIENCE.1709301

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4 November 2022

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M Karplus

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author name string

S. W. Michnick

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M. K. Rosen

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T. J. Wandless

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S. L. Schreiber

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https://syndication.highwire.org/content/doi/10.1126/science.1709301

4 November 2022

publication date

10 May 1991

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language of work or name

English

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work available at URL

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DOI

10.1126/SCIENCE.1709301

https://api.crossref.org/works/10.1126/SCIENCE.1709301

4 November 2022

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252

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issue

5007

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page(s)

836-9

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cites work

Structure of the human class I histocompatibility antigen, HLA-A2

1 reference

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A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

21 April 2017

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Molecular structure of the bilin binding protein (BBP) from Pieris brassicae after refinement at 2.0 A resolution

21 April 2017

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Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

21 April 2017

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β-Sheet topology and the relatedness of proteins

21 April 2017

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https://api.crossref.org/works/10.1126/SCIENCE.1709301

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1709301

Molecular cloning and overexpression of the human FK506-binding protein FKBP

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1709301

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

21 April 2017

1 reference

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Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex

21 April 2017

1 reference

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Solution conformation of proteinase inhibitor IIA from bull seminal plasma by 1H nuclear magnetic resonance and distance geometry

21 April 2017

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Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

21 April 2017

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Cyclophilin: a specific cytosolic binding protein for cyclosporin A

21 April 2017

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Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

21 April 2017

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

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Three-dimensional structure of proteins determined by molecular dynamics with interproton distance restraints: application to crambin

21 January 2018

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Principles that determine the structure of proteins

21 January 2018

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Rapamycin and FK506 binding proteins (immunophilins)

21 January 2018

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A protein structure from nuclear magnetic resonance data. lac repressor headpiece

21 January 2018

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Determination of three-dimensional structures of proteins from interproton distance data by hybrid distance geometry-dynamical simulated annealing calculations

21 January 2018

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Calibration of the angular dependence of the amide proton-C alpha proton coupling constants, 3JHN alpha, in a globular protein. Use of 3JHN alpha for identification of helical secondary structure

21 January 2018

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21 January 2018

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Inhibition of FKBP rotamase activity by immunosuppressant FK506: twisted amide surrogate

21 January 2018

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Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

21 January 2018

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Protein structures in solution by nuclear magnetic resonance and distance geometry. The polypeptide fold of the basic pancreatic trypsin inhibitor determined using two different algorithms, DISGEO and DISMAN.

21 January 2018

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The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

21 January 2018

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Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription

21 January 2018

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1709301

FKBP, thought to be identical to PKCI-2, does not inhibit protein kinase C

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1709301

Proton and nitrogen sequential assignments and secondary structure determination of the human FK506 and rapamycin binding protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1709301

Systematic application of high-resolution, phase-sensitive two-dimensional 1H-NMR techniques for the identification of the amino-acid-proton spin systems in proteins. Rabbit metallothionein-2

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1709301

The peptidyl-prolyl isomerase, FK506-binding protein, is most likely the 12 kd endogenous inhibitor 2 of protein kinase C

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1709301

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1709301

Buildup rates of the nuclear Overhauser effect measured by two-dimensional proton magnetic resonance spectroscopy: implications for studies of protein conformation

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1 reference

DOI

10.1126/SCIENCE.1709301

https://api.crossref.org/works/10.1126/SCIENCE.1709301