The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9 (Q28272159)

https://api.crossref.org/works/10.1016/S0092-8674(00)81182-4

Programmed cell death activator egl-1 CELE_F23B12.9

24 December 2024

main subject

Caenorhabditis elegans

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1 reference

Cell death protein 3 subunit p17 CELE_C48D1.2

GOA release 2020-03-11

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Apoptosis regulator ced-9 CELE_T07C4.8

GOA release 2020-03-11

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GOA release 2020-03-11

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9604928

Caenorhabditis elegans proteins

24 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9604928

24 December 2024

2

H R Horvitz

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Barbara Conradt

1

object named as

B. Conradt

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9604928

http://www.cell.com/article/S0092867400811824/pdf

24 December 2024

publication date

15 May 1998

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language of work or name

English

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work available at URL

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9604928

https://api.elsevier.com/content/article/PII:S0092867400811824?httpAccept=text/xml

24 December 2024

1 reference

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https://api.elsevier.com/content/article/PII:S0092867400811824?httpAccept=text/plain

24 December 2024

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https://api.crossref.org/works/10.1016/S0092-8674(00)81182-4

24 December 2024

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93

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issue

4

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page(s)

519-29

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Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins

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Two C. elegans genes control the programmed deaths of specific cells in the pharynx

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