The taming of a transposon: V(D)J recombination and the immune system (Q28270945)

27 March 2017

author name string

Jessica M Jones

series ordinal

1

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Martin Gellert

series ordinal

2

1 reference

27 March 2017

Jessica M. Jones

series ordinal

1

1 reference

27 March 2017

publication date

August 2004

1 reference

PubMed

PubMed publication ID

22364558

31 January 2017

27 March 2017

language of work or name

English

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published in

Immunological Reviews

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27 March 2017

volume

200

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27 March 2017

issue

1

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27 March 2017

page(s)

233-48

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233-248

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publication type of scholarly work

27 March 2017

review article

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The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

Europe PubMed Central

cites work

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Assembly of a 12/23 Paired Signal Complex: A Critical Control Point in V(D)J Recombination

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Three-dimensional structure of the Tn5 synaptic complex transposition intermediate

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

The RAG1 N-terminal domain is an E3 ubiquitin ligase

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Autoubiquitylation of the V(D)J recombinase protein RAG1

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

Mechanisms underlying ubiquitination

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2004.00168.X

SCF and Cullin/Ring H2-based ubiquitin ligases

21 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Somatic generation of antibody diversity

21 April 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Chromosome organization and genic expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

The V(D)J recombination activating gene, RAG-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

DNA-PK is essential only for coding joint formation in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Intermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

V(D)J recombination: RAG proteins, repair factors, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Complementation of V(D)J Recombination Deficiency in RAG-1−/− B Cells Reveals a Requirement for Novel Elements in the N-Terminus of RAG-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A Basic Motif in the N-Terminal Region of RAG1 Enhances V(D)J Recombination Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Impaired V(D)J recombination and lymphocyte development in core RAG1-expressing mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

The DDE motif in RAG-1 is contributed in trans to a single active site that catalyzes the nicking and transesterification steps of V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Identification of Basic Residues in RAG2 Critical for DNA Binding by the RAG1-RAG2 Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A dimer of the lymphoid protein RAG1 recognizes the recombination signal sequence and the complex stably incorporates the high mobility group protein HMG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Assembly of the RAG1/RAG2 Synaptic Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Stimulation of V(D)J cleavage by high mobility group proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

A RAG-1/RAG-2 tetramer supports 12/23-regulated synapsis, cleavage, and transposition of V(D)J recombination signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Accessibility of nucleosomal DNA to V(D)J cleavage is modulated by RSS positioning and HMG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Comparative architecture of transposase and integrase complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Ordered assembly of the V(D)J synaptic complex ensures accurate recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Functional organization of single and paired V(D)J cleavage complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Mass spectrometry of proteins of known mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Purification and biochemical analyses of a monomeric form of Tn5 transposase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Retroviral integrases and their cousins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Molecular mechanism of retroviral DNA integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Identification of two catalytic residues in RAG1 that define a single active site within the RAG1/RAG2 protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

The same two monomers within a MuA tetramer provide the DDE domains for the strand cleavage and strand transfer steps of transposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Criss-crossed interactions between the enhancer and the att sites of phage Mu during DNA transposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Excision of the Drosophila mariner transposon Mos1. Comparison with bacterial transposition and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Extensive, Nonrandom Diversity of Excision Footprints Generated by Ds-Like Transposon Ascot-1Suggests New Parallels with V(D)J Recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Transposable elements generate novel spatial patterns of gene expression in Antirrhinum majus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

In vivo transposition mediated by V(D)J recombinase in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

The C-terminal portion of RAG2 protects against transposition in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Full-length RAG-2, and Not Full-length RAG-1, Specifically Suppresses RAG-mediated Transposition but Not Hybrid Joint Formation or Disintegration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Tn7 recognizes transposition target structures associated with DNA replication using the DNA-binding protein TnsE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Rejoining of DNA by the RAG1 and RAG2 Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Targeted transposition by the V(D)J recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

Mu transpososome architecture ensures that unfolding by ClpX or proteolysis by ClpXP remodels but does not destroy the complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.00168.X

10.1111/J.0105-2896.2004.00168.X

21 January 2018

Identifiers

DOI

1 reference

release_zg2lcwkwh5hi5eeodw4vmoyka4

27 March 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zg2lcwkwh5hi5eeodw4vmoyka4