The role of the CD44/ezrin complex in cancer metastasis (Q28199313)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12711360%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

The role of the CD44/ezrin complex in cancer metastasis (English)

1 reference

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2 November 2019

1 reference

4

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2 November 2019

author name string

Tracey A Martin

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12711360%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Gregory Harrison

series ordinal

2

1 reference

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2 November 2019

Robert E Mansel

series ordinal

3

1 reference

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2 November 2019

publication date

1 May 2003

1 reference

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Critical Reviews in Oncology Hematology

2 November 2019

language of work or name

English

0 references

published in

1 reference

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2 November 2019

volume

46

1 reference

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2 November 2019

issue

2

1 reference

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2 November 2019

page(s)

165-186

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publication type of scholarly work

2 November 2019

review article

1 reference

Cell adhesion molecules in angiogenesis

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Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor.

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Membrane-actin microfilament connections: an increasing diversity of players related to band 4.1.

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Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins

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Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons

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7 January 2021

Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons

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7 January 2021

The cell adhesion molecule, GP116, is a new CD44 variant (ex14/v10) involved in hyaluronic acid binding and endothelial cell proliferation

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7 January 2021

The ezrin protein family: membrane-cytoskeleton interactions and disease associations

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Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells

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The genetics of the protein 4.1 family: organizers of the membrane and cytoskeleton

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ERM proteins: head-to-tail regulation of actin-plasma membrane interaction

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Regulation of cortical structure by the ezrin-radixin-moesin protein family

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7 January 2021

Distinct cell type-specific expression of scaffolding proteins EBP50 and E3KARP: EBP50 is generally expressed with ezrin in specific epithelia, whereas E3KARP is not.

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7 January 2021

Protein modules as organizers of membrane structure

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7 January 2021

Association of ezrin with intercellular adhesion molecule-1 and -2 (ICAM-1 and ICAM-2). Regulation by phosphatidylinositol 4, 5-bisphosphate

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7 January 2021

High levels of ezrin expressed by human pancreatic adenocarcinoma cell lines with high metastatic potential

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7 January 2021

Interaction of CD44 variant isoforms with hyaluronic acid and the cytoskeleton in human prostate cancer cells

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7 January 2021

Involvement of CD44 and its variant isoforms in membrane-cytoskeleton interaction, cell adhesion and tumor metastasis

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7 January 2021

Interaction between the Adhesion Receptor, CD44, and the Oncogene Product, p185 , Promotes Human Ovarian Tumor Cell Activation

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7 January 2021

A human lymphocyte homing receptor, the hermes antigen, is related to cartilage proteoglycan core and link proteins

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7 January 2021

The hyaluronate receptor is preferentially expressed on proliferating epithelial cells

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7 January 2021

A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Molecular cloning of CD44R1 and CD44R2, two novel isoforms of the human CD44 lymphocyte "homing" receptor expressed by hemopoietic cells

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7 January 2021

Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Biochemical characterization of ezrin-actin interaction

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7 January 2021

Indirect association of ezrin with F-actin: isoform specificity and calcium sensitivity

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Hypoxia increases human keratinocyte motility on connective tissue.

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7 January 2021

ICAM-2 redistributed by ezrin as a target for killer cells

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Identification of a 55-kDa ezrin-related protein that induces cytoskeletal changes and localizes to the nucleolus

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Regulation of CD44-hyaluronan interactions in Burkitt's lymphoma and Epstein-Barr virus-transformed lymphoblastoid B cells by PMA and interleukin-4.

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Interleukins 4 and 13 upregulate expression of cd44 in human colonic epithelial cell lines

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Modulation of CD44 in acute lymphoblastic leukemia identifies functional and phenotypic differences of human B cell precursors

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Oncostatin M and transforming growth factor-beta 1 induce post-translational modification and hyaluronan binding to CD44 in lung-derived epithelial tumor cells

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Influence of cytokines on the expression of fas ligand and CD44 splice variants in colon carcinoma cells

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7 January 2021

TNFalpha and IL-8 regulate the expression and function of CD44 variant proteins in human colon carcinoma cells

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7 January 2021

Epidermal growth factor up-regulates CD44-dependent astrocytoma invasion in vitro

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7 January 2021

Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain

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7 January 2021

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

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7 January 2021

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

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7 January 2021

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

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7 January 2021

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

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7 January 2021

Identification of a phosphatidylinositol-4,5-bisphosphate-binding domain in the N-terminal region of ezrin

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7 January 2021

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

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7 January 2021

Identification of two regions in the cytoplasmic domain of CD44 through which PMA, calcium, and foskolin differentially regulate the binding of CD44 to hyaluronic acid

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

The effect of hyaluronate and its oligosaccharides on endothelial cell proliferation and monolayer integrity

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7 January 2021

Ankyrin-binding domain of CD44(GP85) is required for the expression of hyaluronic acid-mediated adhesion function

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Identification of the ankyrin-binding domain of the mouse T-lymphoma cell inositol 1,4,5-trisphosphate (IP3) receptor and its role in the regulation of IP3-mediated internal Ca2+ release

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

The hyaluronate receptor is associated with actin filaments

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Mouse T lymphoma cells contain a transmembrane glycoprotein (GP85) that binds ankyrin

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

A CD44-like endothelial cell transmembrane glycoprotein (GP116) interacts with extracellular matrix and ankyrin

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Involvement of CD44 variant isoforms in hyaluronate adhesion by human activated T cells

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7 January 2021

Hyaluronan and its binding proteins, the hyaladherins

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7 January 2021

A cell surface integral membrane glycoprotein of 85,000 mol wt (gp85) associated with triton X-100-insoluble cell skeleton

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

The hyaluronate receptor is a member of the CD44 (H-CAM) family of cell surface glycoproteins

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

A novel ligand for CD44 is sulfated proteoglycan

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7 January 2021

CD44 is the principal cell surface receptor for hyaluronate

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7 January 2021

Distinct effects of two CD44 isoforms on tumor growth in vivo

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7 January 2021

A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion

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7 January 2021

Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin

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7 January 2021

CD44 participates in the adhesion of human colorectal carcinoma cells to laminin and type IV collagen

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7 January 2021

Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.

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7 January 2021

Effect of transforming growth factor-beta 1 and basic fibroblast growth factor on the expression of cell surface proteoglycans in human lung fibroblasts. Enhanced glycanation and fibronectin-binding of CD44 proteoglycan, and down-regulation of glypi

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7 January 2021

A sulfated proteoglycan as a novel ligand for CD44.

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7 January 2021

A novel ligand for CD44 is serglycin, a hematopoietic cell lineage-specific proteoglycan. Possible involvement in lymphoid cell adherence and activation

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7 January 2021

The chondroitin sulfate form of invariant chain can enhance stimulation of T cell responses through interaction with CD44.

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7 January 2021

Cytoskeletal changes in cell transformation and tumorigenesis

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7 January 2021

Differential expression of CD44v6 in metastases of intestinal and diffuse types of gastric carcinoma

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7 January 2021

Protein expression of CD44 (standard and variant isoforms) in hepatocellular carcinoma: relationships with tumor grade, clinicopathologic parameters, p53 expression, and patient survival

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7 January 2021

Expression of CD44 standard form and variant isoforms in non-small cell lung carcinomas

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7 January 2021

Expression of CD44v3 splice variant is associated with the visceral metastatic phenotype of human melanoma

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7 January 2021

Expression of CD44 splice variant v10 in Hodgkin's disease is associated with aggressive behaviour and high risk of relapse

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7 January 2021

CD44v6 expression in non-Hodgkin's lymphoma: an association with low histological grade and poor prognosis

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7 January 2021

Expression of CD44 variants and prognosis in oesophageal squamous cell carcinoma

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7 January 2021

Expression of CD44 isoforms in squamous cell carcinoma of the border of the tongue: A correlation with histological grade, pattern of stromal invasion, and cell differentiation

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7 January 2021

Reduced expression of CD44 variant 9 is related to lymph node metastasis and poor survival in squamous cell carcinoma of tongue

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7 January 2021

Expression of CD44 variants and its association with survival in pancreatic cancer

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7 January 2021

Reduced CD44 standard expression is associated with tumour recurrence and unfavourable outcome in differentiated thyroid carcinoma

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7 January 2021

Loss of CD44 variant 6 expression differentiates small cell carcinoma of urinary bladder from urothelial (transitional cell) carcinoma

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Expression of CD44 standard and variant-v6 proteins in transitional cell bladder tumours and their relation to prognosis during a long-term follow-up

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Increasing incidence of CD44v7/8 epitope expression during uterine cervical carcinogenesis

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Altered CD44 variant 6 expression in FIGO stage IB cervical carcinoma.

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Subcellular localization of RhoA and ezrin at membrane ruffles of human endothelial cells: differential role of collagen and fibronectin

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

New CD44 splice variants associated with human breast cancers

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Actin, its associated proteins and metastasis

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Ezrin, a membrane-cytoskeletal linking protein, is involved in the process of invasion of endometrial cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Expression of CD44 and its variant isoform v3 has no prognostic value in gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Expression of moesin and its associated molecule CD44 in epithelial skin tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Moesin and CD44 expression in cutaneous melanocytic tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

The hepatitis B virus X protein (HBx) induces a migratory phenotype in a CD44-dependent manner: possible role of HBx in invasion and metastasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

CD44V6 expression in human colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Expression of CD44v6 has no prognostic value in patients with colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Loss of standard type of CD44 expression in invaded area as a good indicator of lymph-node metastasis in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

The prognostic value of immunohistochemically detected CD44v3 and CD44v6 expression in patients with surgically staged vulvar carcinoma: a multicenter study

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

CD44-9v and CD44-10v are potential molecular markers for squamous cell carcinoma of the vulva

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Prognostic value of CD44 expression in invasive squamous cell carcinoma of the vulva

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

CD44 splice variant expression in clear cell carcinoma of the ovary

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Clear cell carcinoma of the ovary: characterization of its CD44 isoform repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Automated and quantitative immunocytochemical assays of CD44v6 in breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Prognostic value of immunohistochemically detected CD44 isoforms CD44v5, CD44v6 and CD44v7-8 in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Comparison of immunohistochemistry and RT-PCR for detection of CD44v-expression, a new prognostic factor in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Relationship between CD44 expression and differentiation of human prostate adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

CD44 as prognostic factor in oral and oropharyngeal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Preoperative chemoradiotherapy alters the expression and prognostic significance of adhesion molecules in Barrett's-associated adenocarcinoma

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Expression of CD44 variant proteins in adenocarcinoma of Barrett's esophagus and its relation to prognosis

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https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Regulated CD44 cleavage under the control of protein kinase C, calcium influx, and the Rho family of small G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Hyaluronan expression in differentiated thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Ezrin, a membrane-cytoskeletal linking protein, is highly expressed in atypical endometrial hyperplasia and uterine endometrioid adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Ovarian epithelial carcinoma tyrosine phosphorylation, cell proliferation, and ezrin translocation are stimulated by interleukin 1? and epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Altered expression of the ERM proteins in lung adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Moesin expression is associated with the estrogen receptor-negative breast cancer phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

De novo expression of CD44 in prostate carcinoma is correlated with systemic dissemination of prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

CD44 isoform 6 (CD44v6) is a prognostic indicator of the response to neoadjuvant chemotherapy in cervical carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Silencing of CD44 expression in prostate cancer by hypermethylation of the CD44 promoter region

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Hypermethylation of the CD44 gene is associated with progression and metastasis of human prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Expression and prognostic value of CD44 standard and variant v3 and v6 isoforms in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

Decreased CD44 standard form expression correlates with prognostic variables in ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1040-8428%2802%2900172-5

7 January 2021

10.1016/S1040-8428(02)00172-5

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12711360%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017