Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation (Q27930004)

1 December 2016

title

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation (English)

1 reference

1 December 2016

main subject

endoplasmic reticulum

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molecular chaperone

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Jem1p YJL073W

1 reference

GOA release 2020-03-11

Scj1p YMR214W

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Hsp70 family ATPase KAR2 YJL034W

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Y Kato

3

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T Endo

5

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S W Fewell

2

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S I Nishikawa

1

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J L Brodsky

4

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publication date

28 May 2001

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language of work or name

English

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published in

Journal of Cell Biology

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The engagement of Sec61p in the ER dislocation process

1 December 2016

volume

153

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issue

5

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page(s)

1061-70

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cites work

1 reference

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BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane

20 March 2017

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20 March 2017

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Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane

20 March 2017

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A role for the DnaJ homologue Scj1p in protein folding in the yeast endoplasmic reticulum

20 March 2017

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Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

20 March 2017

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The yeast JEM1p is a DnaJ-like protein of the endoplasmic reticulum membrane required for nuclear fusion

20 March 2017

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20 March 2017

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

20 March 2017

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SSI1 encodes a novel Hsp70 of the Saccharomyces cerevisiae endoplasmic reticulum.

20 March 2017

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ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

20 March 2017

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Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo

20 March 2017

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A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors

20 March 2017

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Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.

20 March 2017

1 reference

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The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

20 March 2017

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SSS1 encodes a stabilizing component of the Sec61 subcomplex of the yeast protein translocation apparatus.

20 March 2017

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A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s

20 March 2017

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Rapid and efficient site-specific mutagenesis without phenotypic selection

20 March 2017

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Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases

20 March 2017

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

20 March 2017

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Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum

20 March 2017

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

20 March 2017

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Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

20 March 2017

1 reference

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A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174341

BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast

20 March 2017

1 reference

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Setting the standards: quality control in the secretory pathway

20 March 2017

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Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast

7 April 2017

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Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

7 April 2017

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7 April 2017

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Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK

7 April 2017

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Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

7 April 2017

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Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system

29 September 2017

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ER protein quality control and proteasome-mediated protein degradation

29 September 2017

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Surfing the Sec61 channel: bidirectional protein translocation across the ER membrane.

29 September 2017

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29 September 2017

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Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

29 September 2017

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Ste6p Mutants Defective in Exit from the Endoplasmic Reticulum (ER) Reveal Aspects of an ER Quality Control Pathway inSaccharomyces cerevisiae

29 September 2017

1 reference

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The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiae

29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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2 June 2018

1 reference

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2 June 2018

1 reference

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2 June 2018

1 reference

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2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174341

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2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174341

The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct

27 November 2018

1 reference

12 December 2020

Re-entering the translocon from the lumenal side of the endoplasmic reticulum. Studies on mutated carboxypeptidase yscY species

1 reference

12 December 2020

Distinct domains within yeast Sec61p involved in post-translational translocation and protein dislocation

1 reference

12 December 2020

Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway

1 reference

12 December 2020

Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast

1 reference

12 December 2020

Binding of mitochondrial presequences to yeast cytosolic heat shock protein 70 depends on the amphiphilicity of the presequence

1 reference

12 December 2020

Degradation of a mutant secretory protein, alpha1-antitrypsin Z, in the endoplasmic reticulum requires proteasome activity

1 reference

12 December 2020

Selective inhibitors of the proteasome-dependent and vacuolar pathways of protein degradation in Saccharomyces cerevisiae

1 reference

12 December 2020

Oligomeric Rings of the Sec61p Complex Induced by Ligands Required for Protein Translocation

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12 December 2020

Cer1p, a novel Hsp70-related protein required for posttranslational endoplasmic reticulum translocation in yeast

1 reference

12 December 2020

BiP Maintains the Permeability Barrier of the ER Membrane by Sealing the Lumenal End of the Translocon Pore before and Early in Translocation

1 reference

12 December 2020

Calnexin and BiP interact with acid phosphatase independently of glucose trimming and reglucosylation in Schizosaccharomyces pombe

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.153.5.1061

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1 reference

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